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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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V649629-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $280.90 | |
V649629-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $460.90 |
Alkaloids Other Alkaloids
Synonyms | Vasicine|6159-56-4|1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol|Peganine|(+/-)-Vasicine|Vasicine, dl-|Vasicine, (+/-)-|0VFV53RMC2|1H,2H,3H,9H-PYRROLO[2,1-B]QUINAZOLIN-3-OL|CHEMBL1186527|1,2,3,9-Tetrahydropyrrolo(2,1-b)quinazolin-3-ol|NSC685523|(+/-)-Pe |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | (±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H + -K + -ATPase activityxa0in vitroxa0with an IC 50 of 73.47xa0μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant andxa0cytoprotectivexa0 |
Storage Temp | Store at 2-8°C,Protected from light,Desiccated |
Shipped In | Wet ice |
Product Description | (±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H + -K + -ATPase activity in vitro with an IC 50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect. In Vitro Vasicine (Peganine) exhibits strong antioxidant activity in the DPPH inhibition assay with an IC 50 value of 71.97±3.79 μg/mL. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol |
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INCHI | InChI=1S/C11H12N2O/c14-10-5-6-13-7-8-3-1-2-4-9(8)12-11(10)13/h1-4,10,14H,5-7H2 |
InChi Key | YIICVSCAKJMMDJ-UHFFFAOYSA-N |
Canonical SMILES | C1CN2CC3=CC=CC=C3N=C2C1O |
Isomeric SMILES | C1CN2CC3=CC=CC=C3N=C2C1O |
PubChem CID | 72610 |
Molecular Weight | 188.23 |
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Solubility | DMSO : 16.67 mg/mL (88.56 mM; Need ultrasonic) |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |