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TK:Tyrosine kinase
vecabrutinib , Tyrosine-protein kinase BTK inhibitor, CAS No.1510829-06-7, Tyrosine-protein kinase BTK inhibitor

vecabrutinib , Tyrosine-protein kinase BTK inhibitor, CAS No.1510829-06-7, Tyrosine-protein kinase BTK inhibitor

Item Number

V614719

Grouped product items
SKU	Size	Availability	Price	Qty
V614719-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$240.90
V614719-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,060.90

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Basic Description

Synonyms	Vecabrutinib\|1510829-06-7\|BIIB-062\|Vecabrutinib [INN]\|BSK-4841\|Vecabrutinib [USAN]\|FP0182\|PQ7O0OB5GU\|UNII-PQ7O0OB5GU\|Vecabrutinib [USAN:INN]\|FP-0182\|SNS062\|(3R,3'R,4'S)-1'-(6-amino-5-fluoropyrimidin-4-yl)-3-[3-chloro-5-(trifluoromethyl)anilino]-2-oxo[1,3'
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Tyrosine-protein kinase BTK inhibitor

ALogP	2.7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(3R,4S)-1-(6-amino-5-fluoropyrimidin-4-yl)-3-[(3R)-3-[3-chloro-5-(trifluoromethyl)anilino]-2-oxopiperidin-1-yl]piperidine-4-carboxamide
INCHI	InChI=1S/C22H24ClF4N7O2/c23-12-6-11(22(25,26)27)7-13(8-12)32-15-2-1-4-34(21(15)36)16-9-33(5-3-14(16)19(29)35)20-17(24)18(28)30-10-31-20/h6-8,10,14-16,32H,1-5,9H2,(H2,29,35)(H2,28,30,31)/t14-,15+,16-/m0/s1
InChi Key	QLRRJMOBVVGXEJ-XHSDSOJGSA-N
Canonical SMILES	C1CC(C(=O)N(C1)C2CN(CCC2C(=O)N)C3=NC=NC(=C3F)N)NC4=CC(=CC(=C4)C(F)(F)F)Cl
Isomeric SMILES	C1C[C@H](C(=O)N(C1)[C@H]2CN(CC[C@@H]2C(=O)N)C3=NC=NC(=C3F)N)NC4=CC(=CC(=C4)C(F)(F)F)Cl
Alternate CAS	1510829-06-7
PubChem CID	72547837
MeSH Entry Terms	(3R,4S)-1-(6-amino-5-fluoropyrimidin-4-yl)-3-((3R)-3-(3-chloro-5-(trifluoromethyl)anilino)-2-oxopiperidin-1-yl)piperidine-4-carboxamide;vecabrutinib
Molecular Weight	529.9

CAS Registry No.	1510829-06-7
PubChem CID	72547837

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