Vedolizumab (anti-α4β7-integrin) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to Integrin a4b7 (ITGA4 & ITGB7), >95%, high purity, Human IgG1, Antibody of integrin α4β7
Vedolizumab (anti-α4β7-integrin) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to Integrin a4b7 (ITGA4 & ITGB7), >95%, high purity, Human IgG1, Antibody of integrin α4β7
Vedolizumab (anti-α4β7-integrin) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to Integrin a4b7 (ITGA4 & ITGB7), >95%, high purity, Human IgG1
Vedolizumab is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease. Purity >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg
Product Properties
Antibody Type
Primary antibody
Clonality
Recombinant
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
26.5 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 178.5 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Purity
>95%
Source
CHO supernatant
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS
943609-66-3
Images
Vedolizumab (anti-α4β7-integrin) (Ab169270) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling α4β7-integrin (red) with Vedolizumab (anti-α4β7-integrin) (Ab169270). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (
Ab170213
). Black - Unlabelled control, cells without incubation with primary antibody.
Vedolizumab (anti-α4β7-integrin) (Ab169270) - SEC The purity of Vedolizumab (anti-α4β7-integrin) (Ab169270) is more than 95% verified by HPLC.
1.Soler D, Chapman T, Yang LL, Wyant T, Egan R, Fedyk ER. (2009) The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases.. J Pharmacol Exp Ther, 330 (3):(864-75). [PMID:19509315]
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