Click Here for 5% Off Your First Aladdin Purchase!

Venlafaxine hydrochloride - ≥98% (HPLC), high purity , Norepinephrine transporter inhibitor, CAS No.99300-78-4, Norepinephrine transporter inhibitor

  • ≥98%(HPLC)
Item Number
V129637
Grouped product items
SKUSizeAvailabilityPrice Qty
V129637-1g
1g
In stock
$71.90
V129637-5g
5g
In stock
$218.90
V129637-25g
25g
In stock
$983.90
V129637-100g
100g
In stock
$3,539.90

Serotonin-norepinephrine reuptake inhibitor

Basic Description

SynonymsVenlafaxine hydrochloride|99300-78-4|VENLAFAXINE HCl|Effexor|Vandral|Efexor|Effexor XR|Dobupal|Venlafaxinehydrochloride|Wy-45030|Venlafaxine (hydrochloride)|Wy 45030|Wy-45,030|1-(2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol hydrochloride|Wy 450
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsVenlafaxine Hydrochloride is a dual ST and SLC6A2 (serotonin and noradrenalin re-uptake) inhibitor that displays ~ 30-fold higher affinity for ST (SERT) (Ki = 82 nm) than SLC6A2 (NET) (Ki = 2480 nM).Serotonin-norepinephrine reuptake inhibitor. K i values
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionNorepinephrine transporter inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Venlafaxine hydrochloride is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI).
An inhibitor of ST and SLC6A2.

Associated Targets

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 8 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol;hydrochloride
INCHI InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChi Key QYRYFNHXARDNFZ-UHFFFAOYSA-N
Canonical SMILES CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl
Isomeric SMILES CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl
WGK Germany 3
RTECS GV8872760
Alternate CAS 93413-69-5
PubChem CID 62923
Molecular Weight 313.86
Reaxy-Rn 4240401

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

7 results found

Lot NumberCertificate TypeDateItem
I2212425Certificate of AnalysisJun 20, 2024 V129637
I2212432Certificate of AnalysisJun 20, 2024 V129637
I2212438Certificate of AnalysisJun 20, 2024 V129637
I2212445Certificate of AnalysisJun 20, 2024 V129637
I2007248Certificate of AnalysisJul 12, 2022 V129637
I2007247Certificate of AnalysisJul 12, 2022 V129637
G2201681Certificate of AnalysisJul 06, 2022 V129637

Chemical and Physical Properties

SolubilitySoluble in water (>25 mg/ml), and DMSO (50 mM)
SensitivityLight sensitive
Melt Point(°C)217°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H302:Harmful if swallowed

H362:May cause harm to breast-fed children

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P263:Avoid contact during pregnancy/while nursing.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RTECS GV8872760
Reaxy-Rn 4240401
Merck Index 9946

Related Documents

Solution Calculators