Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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V129637-1g | 1g | In stock | $71.90 | |
V129637-5g | 5g | In stock | $218.90 | |
V129637-25g | 25g | In stock | $983.90 | |
V129637-100g | 100g | In stock | $3,539.90 |
Serotonin-norepinephrine reuptake inhibitor
Synonyms | Venlafaxine hydrochloride|99300-78-4|VENLAFAXINE HCl|Effexor|Vandral|Efexor|Effexor XR|Dobupal|Venlafaxinehydrochloride|Wy-45030|Venlafaxine (hydrochloride)|Wy 45030|Wy-45,030|1-(2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol hydrochloride|Wy 450 |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Venlafaxine Hydrochloride is a dual ST and SLC6A2 (serotonin and noradrenalin re-uptake) inhibitor that displays ~ 30-fold higher affinity for ST (SERT) (Ki = 82 nm) than SLC6A2 (NET) (Ki = 2480 nM).Serotonin-norepinephrine reuptake inhibitor. K i values |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | INHIBITOR |
Mechanism of action | Norepinephrine transporter inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Venlafaxine hydrochloride is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI). |
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IUPAC Name | 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol;hydrochloride |
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INCHI | InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H |
InChi Key | QYRYFNHXARDNFZ-UHFFFAOYSA-N |
Canonical SMILES | CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl |
Isomeric SMILES | CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl |
WGK Germany | 3 |
RTECS | GV8872760 |
Alternate CAS | 93413-69-5 |
PubChem CID | 62923 |
Molecular Weight | 313.86 |
Reaxy-Rn | 4240401 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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I2212425 | Certificate of Analysis | Jun 20, 2024 | V129637 |
I2212432 | Certificate of Analysis | Jun 20, 2024 | V129637 |
I2212438 | Certificate of Analysis | Jun 20, 2024 | V129637 |
I2212445 | Certificate of Analysis | Jun 20, 2024 | V129637 |
I2007248 | Certificate of Analysis | Jul 12, 2022 | V129637 |
I2007247 | Certificate of Analysis | Jul 12, 2022 | V129637 |
G2201681 | Certificate of Analysis | Jul 06, 2022 | V129637 |
Solubility | Soluble in water (>25 mg/ml), and DMSO (50 mM) |
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Sensitivity | Light sensitive |
Melt Point(°C) | 217°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed H362:May cause harm to breast-fed children |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. |
WGK Germany | 3 |
RTECS | GV8872760 |
Reaxy-Rn | 4240401 |
Merck Index | 9946 |