Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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V274917-1mg | 1mg | In stock | $10.90 | |
V274917-5mg | 5mg | In stock | $40.90 | |
V274917-10mg | 10mg | In stock | $64.90 | |
V274917-25mg | 25mg | In stock | $128.90 | |
V274917-50mg | 50mg | In stock | $205.90 | |
V274917-100mg | 100mg | In stock | $328.90 | |
V274917-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $657.90 |
Potent hedgehog pathway inhibitor
Synonyms | VERATRAMINE|60-70-8|NSC 17821|(3beta,23beta)-14,15,16,17-Tetradehydroveratraman-3,23-diol|NSC17821|NSC23880|CHEBI:9951|RK363YG315|NSC-17821|NSC-23880|(2S,3R,5S)-2-[(1S)-1-[(3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]f |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Potent hedgehog pathway inhibitor. Shows antitumor and antiplatelet aggregation effects in vivo . Centrally active and blood-brain barrier permeable. |
Source | Synthetic |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | (2S,3R,5S)-2-[(1S)-1-[(3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol |
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INCHI | InChI=1S/C27H39NO2/c1-15-11-25(30)26(28-14-15)17(3)20-7-8-21-22-6-5-18-12-19(29)9-10-27(18,4)24(22)13-23(21)16(20)2/h5,7-8,15,17,19,22,24-26,28-30H,6,9-14H2,1-4H3/t15-,17-,19-,22-,24-,25+,26-,27-/m0/s1 |
InChi Key | MALFODICFSIXPO-KFKQDBFTSA-N |
Canonical SMILES | CC1CC(C(NC1)C(C)C2=C(C3=C(C=C2)C4CC=C5CC(CCC5(C4C3)C)O)C)O |
Isomeric SMILES | C[C@H]1C[C@H]([C@@H](NC1)[C@@H](C)C2=C(C3=C(C=C2)[C@@H]4CC=C5C[C@H](CC[C@@]5([C@H]4C3)C)O)C)O |
PubChem CID | 6070 |
Molecular Weight | 409.6 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2430393 | Certificate of Analysis | May 13, 2024 | V274917 |
G2430394 | Certificate of Analysis | May 13, 2024 | V274917 |
G2430395 | Certificate of Analysis | May 13, 2024 | V274917 |
G2430396 | Certificate of Analysis | May 13, 2024 | V274917 |
B2423231 | Certificate of Analysis | Jan 30, 2024 | V274917 |
B2423232 | Certificate of Analysis | Jan 30, 2024 | V274917 |
B2423244 | Certificate of Analysis | Jan 30, 2024 | V274917 |
J2310189 | Certificate of Analysis | Sep 20, 2023 | V274917 |
C2215067 | Certificate of Analysis | Dec 15, 2022 | V274917 |
C2215081 | Certificate of Analysis | Dec 15, 2022 | V274917 |
C2215093 | Certificate of Analysis | Dec 15, 2022 | V274917 |
C2215096 | Certificate of Analysis | Dec 15, 2022 | V274917 |
C2215097 | Certificate of Analysis | Dec 15, 2022 | V274917 |
C2215098 | Certificate of Analysis | Dec 15, 2022 | V274917 |
C2215082 | Certificate of Analysis | Dec 28, 2021 | V274917 |
C2215099 | Certificate of Analysis | Dec 28, 2021 | V274917 |
Solubility | Soluble in Ethanol;Soluble in methanol, chloroform, alcohol, benzene, slightly soluble in water |
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Sensitivity | Heat Sensitive |
Specific Rotation[α] | -66° (C=0.5,CHCl3) |
Melt Point(°C) | 208.0 to 212.0 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. |
Merck Index | 9952 |
Starting at $47.90