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Verlukast - 98%, high purity , CAS No.120443-16-5, Antagonist of CysLT 1 receptor;Inhibitor of OATP2B1

Moligand™
≥98%

CAS#: 120443-16-5
Formula: C₂₆H₂₇ClN₂O₃S₂
Molecular Weight: 515.09
PubChem CID: 6509849

Item Number

V127296

Grouped product items
SKU	Size	Availability	Price	Qty
V127296-5mg	5mg	In stock	$236.90
V127296-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,066.90

View related series

CysLT1 receptor Antagonist OATP2B1 Inhibitor

Basic Description

Synonyms	VERLUKAST\|120443-16-5\|MK-679\|MK-0679\|CHEMBL280481\|5Q9O54P0H7\|L-668,019\|Verlukastum\|L-668019\|MK 679\|(R,E)-3-(((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoic acid\|Propanoic acid, 3-(((3-(2-(7-chloro-2-qu
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Verlukast(MK-679; L 668019) is a receptor antagonist for the treatment of respiratory diseases.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ANTAGONIST, INHIBITOR
Mechanism of action	Antagonist of CysLT 1 receptor;Inhibitor of OATP2B1
Product Description	Product Application: A receptor antagonist for the treatment of respiratory diseases.

Associated Targets

SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 1 Activities

Discover Target: SLCO2B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 3 Activities

Discover Target: CYSLTR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCC1 Tchem Multidrug resistance-associated protein 1 0 Activities

Discover Target: ABCC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	3-[(R)-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoic acid
INCHI	InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+/t26-/m1/s1
InChi Key	AXUZQJFHDNNPFG-LHAVAQOQSA-N
Canonical SMILES	CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O
Isomeric SMILES	CN(C)C(=O)CCS[C@@H](C1=CC=CC(=C1)/C=C/C2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O
PubChem CID	6509849
Molecular Weight	515.09

CAS Registry No.

PubChem CID

ChEMBL Ligand

Reactome Reaction

Reactome Drug

GPCRdb Ligand

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
C2313305	Certificate of Analysis	Jan 07, 2023	V127296
C2313309	Certificate of Analysis	Jan 07, 2023	V127296

Solubility

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), THF (Slightly, Sonicate)

Melt Point(°C)

57-62°C

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