| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| V659354-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,800.90 |
| Specifications & Purity | 98% |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | VHL Ligand 8 is a VHL ligand. VHL Ligand 8 can be used to synthesize ARD-266 ( HY-133020 ), a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces degradation of AR protein in AR-positive LNCaP, VCaP, a Appearance:Solid IC50& Target:VHL Biological Activity:VHL Ligand 8 is a VHL ligand. VHL Ligand 8 can be used to synthesize ARD-266 ( HY-133020 ), a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces degradation of AR protein in AR-positive LNCaP, VCaP, a |
| Canonical SMILES | OC(C[C@@H](C1=CC=CC=C1)NC([C@H]2N(C([C@H](C(C)C)C3=CC(C)=NO3)=O)C[C@H](O)C2)=O)=O |
|---|---|
| Molecular Weight | 443.49 |
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| Solubility | DMSO : 100 mg/mL (225.48 mM; Need ultrasonic) H2O : 25 mg/mL (56.37 mM; Need ultrasonic) |
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