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Vilanterol - ≥98%, high purity , CAS No.503068-34-6, Agonist of β 2-adrenoceptor
Basic Description Synonyms Vilanterol|503068-34-6|GW642444x|GW-642444x|UNII-028LZY775B|CHEBI:75037|GW642444|GW-642444|028LZY775B|Vilanterol (USAN)|4-[(1R)-2-[(6-{2-[(2,6-dichlorophenyl)methoxy]ethoxy}hexyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol|4-[(1R)-2-[6-[2-[(2,6-dichlor Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms in vitro:Vilanterol displayed a subnanomolar affinity for the β(2)-AR that was comparable with that of salmeterol but higher than olodaterol, formoterol, and indacaterol. In cAMP functional activity studies, vilanterol demonstrated similar selectivity as Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of β 2-adrenoceptor Note 5mg、50mg、25mg卖完停产，不再备货 Product Description Vilanterol (GW642444; GW 642444X) is a novel, inhaled, long-acting β(2) agonist with inherent 24-h activity under development as a once-daily combination therapy with an inhaled corticosteroid for COPD and asthma.
Names and Identifiers IUPAC Name 4-[(1R)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol INCHI InChI=1S/C24H33Cl2NO5/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28/h5-9,14,24,27-30H,1-4,10-13,15-17H2/t24-/m0/s1 InChi Key DAFYYTQWSAWIGS-DEOSSOPVSA-N Canonical SMILES C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O)Cl Isomeric SMILES C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNC[C@@H](C2=CC(=C(C=C2)O)CO)O)Cl PubChem CID 10184665 Molecular Weight 486.43
Chemical and Physical Properties Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS09 Signal Danger Hazard Statements H411: Toxic to aquatic life with long lasting effects
H370: Causes damage to organs
Precautionary Statements P273: Avoid release to the environment.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P391: Collect spillage.
P308+P316: IF exposed or concerned: Get emergency medical help immediately.
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E1712147