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VU 590 dihydrochloride - ≥97%, high purity , CAS No.313505-85-0

  • ≥97%
Item Number
V335123
Grouped product items
SKUSizeAvailabilityPrice Qty
V335123-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$103.90
V335123-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$418.90

Discover VU 590 dihydrochloride by Aladdin Scientific in ≥97% for only $103.90. Available - in Ligands at Aladdin Scientific. an inhibitor of the renal, outer medullary potassium channel, KIR7.1 Tags: .

Basic Description

SynonymsVU 590 dihydrochloride|313505-85-0|VU590 dihydrochloride|1783987-83-6|VU590 HCl|VU590 (hydrochloride)|VU590 (dihydrochloride)|VU 590|7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane;dihydrochloride|7,13-bis[(4-nitrophenyl)methyl]-1
Specifications & Purity≥97%
Storage TempStore at -20°C,Desiccated
Shipped InDry ice
Product Description

VU 590 dihydrochloride has been reported to inhibit the renal, outer medullary potassium channel (ROMK, KIR1.1) while also able to inhibit the inward rectifying potassium channel KIR7.1. This comppound is also reported to not display an effect towards KIR2.1 or KIR4.1 and additionally acts as an intracellular ROMK channel pore blocker.

Names and Identifiers

IUPAC Name 7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane;dihydrochloride
INCHI InChI=1S/C24H32N4O7.2ClH/c29-27(30)23-5-1-21(2-6-23)19-25-9-13-33-14-10-26(12-16-35-18-17-34-15-11-25)20-22-3-7-24(8-4-22)28(31)32;;/h1-8H,9-20H2;2*1H
InChi Key FRYYSUBAHIUBNJ-UHFFFAOYSA-N
Canonical SMILES C1COCCN(CCOCCOCCN1CC2=CC=C(C=C2)[N+](=O)[O-])CC3=CC=C(C=C3)[N+](=O)[O-].Cl.Cl
Isomeric SMILES C1COCCN(CCOCCOCCN1CC2=CC=C(C=C2)[N+](=O)[O-])CC3=CC=C(C=C3)[N+](=O)[O-].Cl.Cl
PubChem CID 71433535

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO (100 mM).

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

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