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VU0155069 - ≥98%, high purity , CAS No.1130067-06-9

  • ≥98%
Item Number
V275370
Grouped product items
SKUSizeAvailabilityPrice Qty
V275370-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$26.90
V275370-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$328.90
V275370-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
V275370-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$970.90
V275370-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$549.90
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Potent and selective PLD1 inhibitor

Basic Description

SynonymsCAY10593
Specifications & Purity≥98%
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
Product Description

VU0155069 (CAY10593), compound 69, is a selective phospholipase D1 (PLD1) inhibitor with an IC50 value of 46 nM in vitro. VU0155069 (CAY10593) strongly inhibits the invasive migration of several cancer cell lines in transwell assays

Names and Identifiers

IUPAC Name N-[(2S)-1-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]naphthalene-2-carboxamide;hydrochloride
INCHI InChI=1S/C26H27ClN4O2.ClH/c1-17(28-25(32)20-7-6-18-4-2-3-5-19(18)14-20)16-30-12-10-22(11-13-30)31-24-9-8-21(27)15-23(24)29-26(31)33;/h2-9,14-15,17,22H,10-13,16H2,1H3,(H,28,32)(H,29,33);1H/t17-;/m0./s1
InChi Key RQULTQQAHGYYDG-LMOVPXPDSA-N
Canonical SMILES CC(CN1CCC(CC1)N2C3=C(C=C(C=C3)Cl)NC2=O)NC(=O)C4=CC5=CC=CC=C5C=C4.Cl
Isomeric SMILES C[C@@H](CN1CCC(CC1)N2C3=C(C=C(C=C3)Cl)NC2=O)NC(=O)C4=CC5=CC=CC=C5C=C4.Cl
Alternate CAS 1781834-89-6
PubChem CID 56972237
Molecular Weight 462.97

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2410670Certificate of AnalysisMar 18, 2024 V275370
G2410671Certificate of AnalysisMar 18, 2024 V275370
G2410672Certificate of AnalysisMar 18, 2024 V275370
G2410673Certificate of AnalysisMar 18, 2024 V275370
G2410674Certificate of AnalysisMar 18, 2024 V275370
G2410675Certificate of AnalysisMar 18, 2024 V275370
G2410676Certificate of AnalysisMar 18, 2024 V275370
G2410677Certificate of AnalysisMar 18, 2024 V275370
G2410678Certificate of AnalysisMar 18, 2024 V275370
G2410679Certificate of AnalysisMar 18, 2024 V275370

Chemical and Physical Properties

SolubilitySoluble in DMSO to 50 mM or ethanol to 50 mM

Related Documents

 SDS

 Specification Sheet

References

1. Chakraborti S et al..  (2019)  Role of PLD-PKCζ signaling axis in p47phox phosphorylation for activation of NADPH oxidase by angiotensin II in pulmonary artery smooth muscle cells..  Cell Biol Int,  43  (6): (678-694).  [PMID:30977575]

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