X77 is a potent non-covalent inhibitor of the main protease of SARS-CoV-2 ( SARS-CoV-2 M pro ) X77 binds to SARS-CoV-2 M pro with a K d value of 0.057 μM .
In Vitro
X77 can bind to SARS-CoV-2 M pro (PDB code: 6W63). SARS-CoV-2 M pro (PDB code: 6W63) is the main protease of SARS-CoV-2 and is one of the most important drug targets among coronaviruses. MCE has not independently confirmed the accuracy of these methods. They are for reference only.