XAV 939

Item Number
X753399-GMP
Grouped product items
SKUSizeAvailabilityPrice Qty
X753399-GMP-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,220.90

XAV 939 synthesized to cGMP guidelines

Basic Description

Specifications & PurityGMP, ≥99%
Storage TempRoom temperature
Shipped InNormal
GradeGMP
Product Description

Tankyrase Inhibitor; inhibits WNT signaling. Promotes cardiomyocyte differentiation from ESCs

Names and Identifiers

IUPAC Name 2-[4-(trifluoromethyl)phenyl]-3,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one
INCHI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChi Key KLGQSVMIPOVQAX-UHFFFAOYSA-N
Canonical SMILES C1CSCC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F
Isomeric SMILES C1CSCC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F
WGK Germany 3
PubChem CID 135418940
Molecular Weight 312.31

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS07
Signal Danger
Hazard Statements

H319:Causes serious eye irritation

H301:Toxic if swallowed

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3

Related Documents

Citations of This Product

1. Xin Wang, Shoulin Li, Cheng Zhang, Wenping Xu, Mengqi Wu, Jiagao Cheng, Zhong Li, Liming Tao, Yang Zhang.  (2024)  Stereoselective toxicity of acetochlor chiral isomers on the nervous system of zebrafish larvae.  JOURNAL OF HAZARDOUS MATERIALS,  464  (15): (133016).  [PMID:37992503]
2. Yuan Xu, Jian He, Jun He.  (2022)  Cyanidin attenuates the high hydrostatic pressure-induced degradation of cellular matrix of nucleus pulposus cell via blocking the Wnt/β-catenin signaling.  TISSUE & CELL,  76  (101798).  [PMID:35472676]

References

1. Xin Wang, Shoulin Li, Cheng Zhang, Wenping Xu, Mengqi Wu, Jiagao Cheng, Zhong Li, Liming Tao, Yang Zhang.  (2024)  Stereoselective toxicity of acetochlor chiral isomers on the nervous system of zebrafish larvae.  JOURNAL OF HAZARDOUS MATERIALS,  464  (15): (133016).  [PMID:37992503]
2. Yuan Xu, Jian He, Jun He.  (2022)  Cyanidin attenuates the high hydrostatic pressure-induced degradation of cellular matrix of nucleus pulposus cell via blocking the Wnt/β-catenin signaling.  TISSUE & CELL,  76  (101798).  [PMID:35472676]

Solution Calculators