| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Y753425-GMP-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,443.90 |
Y-27632 synthesized to cGMP guidelines
| Specifications & Purity | GMP, ≥99% |
|---|---|
| Storage Temp | Room temperature |
| Shipped In | Normal |
| Grade | GMP |
| Product Description | Selective ROCK Inhibitor. Increases survival of ESCs and iPSCs undergoing cryopreservation |
| IUPAC Name | 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride |
|---|---|
| INCHI | InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1 |
| InChi Key | IDDDVXIUIXWAGJ-DDSAHXNVSA-N |
| Canonical SMILES | Cl.Cl.C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 |
| Isomeric SMILES | C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
| WGK Germany | 3 |
| Molecular Weight | 320.26 |
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| Specific Rotation[α] | +4.0° (C=1,MeOH) |
|---|---|
| Melt Point(°C) | 252 °C |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. |
| WGK Germany | 3 |
| 1. Fan Zhao, Luchen Sun, Nanfei Yang, Wei Zheng, Pingping Shen, Yahong Huang, Yan Lu. (2020) Increased release of microvesicles containing mitochondria is associated with the myeloid differentiation of AML-M5 leukaemia cells. EXPERIMENTAL CELL RESEARCH, 395 (112213). [PMID:32758487] [10.1016/j.yexcr.2020.112213] |
| 1. Fan Zhao, Luchen Sun, Nanfei Yang, Wei Zheng, Pingping Shen, Yahong Huang, Yan Lu. (2020) Increased release of microvesicles containing mitochondria is associated with the myeloid differentiation of AML-M5 leukaemia cells. EXPERIMENTAL CELL RESEARCH, 395 (112213). [PMID:32758487] [10.1016/j.yexcr.2020.112213] |
