YKL-06-062 - 99%, high purity , CAS No.2172617-16-0

Item Number

Y649680

Grouped product items
SKU	Size	Availability	Price
Y649680-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$280.90
Y649680-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$450.90
Y649680-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,500.90
Y649680-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,400.90

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Basic Description

Specifications & Purity	99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC 50 of 2.12 nM/1.40 nM/2.86 nM for SIK1 , SIK2 and SIK3 , respectively. In Vitro YKL 06-062 (0.0004-16 μM; 3 hours) increases MITF mRNA expression in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. RT-PCRCell Line: Human melanocyte cells, UACC62 melanoma cells Concentration: 0.0004 μM, 0.004 μM, 0.04 μM, 0.4 μM, 4 μM,8 μM,16 μM Incubation Time: 3 hours Result: Unregulated MITF mRNA expression. Form:Solid

Names and Identifiers

IUPAC Name	1-cyclohexyl-3-(2,6-dimethylphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-4H-pyrimido[4,5-d]pyrimidin-2-one
INCHI	InChI=1S/C31H39N7O/c1-22-8-7-9-23(2)28(22)37-21-24-20-32-30(34-29(24)38(31(37)39)27-10-5-4-6-11-27)33-25-12-14-26(15-13-25)36-18-16-35(3)17-19-36/h7-9,12-15,20,27H,4-6,10-11,16-19,21H2,1-3H3,(H,32,33,34)
InChi Key	GFXPGVPPWWPDPV-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C(=CC=C1)C)N2CC3=CN=C(N=C3N(C2=O)C4CCCCC4)NC5=CC=C(C=C5)N6CCN(CC6)C
PubChem CID	139600310
Molecular Weight	525.69

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Basic Description