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Yoda 1 - 98%, high purity , CAS No.448947-81-7, Activator of Piezo1
Basic Description Synonyms 448947-81-7|Yoda1|Yoda 1|GlyT2-IN-1|YODA-1|2-((2,6-dichlorobenzyl)thio)-5-(pyrazin-2-yl)-1,3,4-thiadiazole|TW6GF9RW6S|2-[(2,6-dichlorophenyl)methylsulfanyl]-5-pyrazin-2-yl-1,3,4-thiadiazole|CHEMBL4303374|2-[5-(2,6-Dichloro-benzylsulfanyl)-[1,3,4]thiadiazo Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms Piezo1 channel activator. Slows the inactivation phase of transient currents, sensitizes Piezo1 to activation by pressure, and partially activates channels in the absence of external pressure, in HEK cells expressing Piezo1 channels. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ACTIVATOR Mechanism of action Activator of Piezo1
Names and Identifiers IUPAC Name 2-[(2,6-dichlorophenyl)methylsulfanyl]-5-pyrazin-2-yl-1,3,4-thiadiazole INCHI InChI=1S/C13H8Cl2N4S2/c14-9-2-1-3-10(15)8(9)7-20-13-19-18-12(21-13)11-6-16-4-5-17-11/h1-6H,7H2 InChi Key BQNXBSYSQXSXPT-UHFFFAOYSA-N Canonical SMILES C1=CC(=C(C(=C1)Cl)CSC2=NN=C(S2)C3=NC=CN=C3)Cl Isomeric SMILES C1=CC(=C(C(=C1)Cl)CSC2=NN=C(S2)C3=NC=CN=C3)Cl PubChem CID 2746822 Molecular Weight 355.27
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 7.11, Max Conc. mM: 20
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
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I2203457