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YS-49 - ≥98%, high purity , CAS No.132836-42-1

  • ≥98%
Item Number
Y125277
Grouped product items
SKUSizeAvailabilityPrice Qty
Y125277-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Y125277-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
Y125277-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
Y125277-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
Y125277-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90
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Adrenergic Receptor

Basic Description

SynonymsYS-49|132836-42-1|YS 49|1-(naphthalen-1-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol Hydrobromide|1-(naphthalen-1-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrobromide|YS49|DTXSID50437347|BCP06489|MFCD20926418|AKOS030526408|HY-15477|MS-26370
Specifications & Purity≥98%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors.

Names and Identifiers

IUPAC Name 1-(naphthalen-1-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrobromide
INCHI InChI=1S/C20H19NO2.BrH/c22-19-11-15-8-9-21-18(17(15)12-20(19)23)10-14-6-3-5-13-4-1-2-7-16(13)14;/h1-7,11-12,18,21-23H,8-10H2;1H
InChi Key JXFRKNGQHAAJKY-UHFFFAOYSA-N
Canonical SMILES C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=CC4=CC=CC=C43.Br
Isomeric SMILES C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=CC4=CC=CC=C43.Br
PubChem CID 10249534
Molecular Weight 386.28

Certificates

Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
G2403690Certificate of AnalysisJun 07, 2024 Y125277
G2403691Certificate of AnalysisJun 07, 2024 Y125277
G2403692Certificate of AnalysisJun 07, 2024 Y125277
G2403693Certificate of AnalysisJun 07, 2024 Y125277
G2403694Certificate of AnalysisJun 07, 2024 Y125277
G2403695Certificate of AnalysisJun 07, 2024 Y125277
G2403709Certificate of AnalysisJun 07, 2024 Y125277

Chemical and Physical Properties

SolubilityDMSO

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

H400:Very toxic to aquatic life

Precautionary Statements

P273:Avoid release to the environment.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

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