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ZK 93426 hydrochloride - ≥99%, high purity , CAS No.89592-45-0, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit

Moligand™
≥99%

CAS#: 89592-45-0
Formula: C₁₈H₂₀N₂O₃
Molecular Weight: 312.36
PubChem CID: 115210

Item Number

Z338499

Grouped product items
SKU	Size	Availability	Price	Qty
Z338499-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$160.90
Z338499-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$665.90

a elective and competitive benzodiazepine receptor antagonist

View related series

GABAA receptor α1 subunit Allosteric modulator GABAA receptor α2 subunit Allosteric modulator GABAA receptor α3 subunit Allosteric modulator GABAA receptor α5 subunit Allosteric modulator

Basic Description

Synonyms	89592-45-0\|ZK93426\|ZK-93426\|ZK 93426\|Ethyl 4-methyl-5-(1-methylethoxy)-9H-pyrido(3,4-b)indole-3-carboxylate\|S8EEB2VSB3\|CHEMBL1271047\|ethyl 5-isopropoxy-4-methyl-9H-pyrido[3,4-b]indole-3-carboxylate\|ethyl 4-methyl-5-(propan-2-yloxy)-9H-pyrido[3,4-b]indole-
Specifications & Purity	Moligand™, ≥99%
Storage Temp	Room temperature,Desiccated
Shipped In	Normal
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit
Product Description	ZK 93426 hydrochloride is a potent, selective and competitive benzodiazepine receptor antagonist (IC\|50\|values are 0.4 and 0.7 nM for inhibition of [3H]-flunitrazepam binding to rat cerebellum and hippocampus respectively).

Associated Targets

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

Discover Target: GABRA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRG2 Tclin Gamma-aminobutyric acid receptor subunit gamma-2 0 Activities

Discover Target: GABRG2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA3 Tclin Gamma-aminobutyric acid receptor subunit alpha-3 0 Activities

Discover Target: GABRA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA5 Tclin Gamma-aminobutyric acid receptor subunit alpha-5 0 Activities

Discover Target: GABRA5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA2 Tclin Gamma-aminobutyric acid receptor subunit alpha-2 0 Activities

Discover Target: GABRA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Discover Target: FTL

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Discover Target: KMT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX15B Tchem Arachidonate 15-lipoxygenase B 0 Activities

Discover Target: ALOX15B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Discover Target: MAPT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	ethyl 4-methyl-5-propan-2-yloxy-9H-pyrido[3,4-b]indole-3-carboxylate
INCHI	InChI=1S/C18H20N2O3/c1-5-22-18(21)17-11(4)15-13(9-19-17)20-12-7-6-8-14(16(12)15)23-10(2)3/h6-10,20H,5H2,1-4H3
InChi Key	VMDUABMKBUKKPG-UHFFFAOYSA-N
Canonical SMILES	CCOC(=O)C1=NC=C2C(=C1C)C3=C(N2)C=CC=C3OC(C)C
Isomeric SMILES	CCOC(=O)C1=NC=C2C(=C1C)C3=C(N2)C=CC=C3OC(C)C
PubChem CID	115210
Molecular Weight	312.36

PubChem CID

Wikipedia

CAS Registry No.

ChEMBL Ligand

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