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Zofenoprilat Sodium Salt , CAS No.75176-37-3, Inhibitor of Angiotensin-converting enzyme

  • Moligand™
Item Number
Z333288
Grouped product items
SKUSizeAvailabilityPrice Qty
Z333288-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$266.90

an active free sulfhydryl compound of Zenopril

Basic Description

SynonymsZofenoprilat|75176-37-3|Zofenoprilate|Zofenoprilatum|Zofenoprilat [INN]|4G4WDK2YBS|CHEMBL16332|L-PROLINE, 1-[(2S)-3-MERCAPTO-2-METHYL-1-OXOPROPYL]-4-(PHENYLTHIO)-, 4S|(2S,4S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic a
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of Angiotensin-converting enzyme
Product Description

Zofenoprilat is the active free sulfhydryl compound of Zenopril. Zenopril is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. Endothelial membrane studies have demonstrated that Zofenoprilat induces the bradykinin B1 receptors, which activates the expression of FGF-2. Studies show that Zofenoprilat is more effective than Enalaprilat at protecting pancreatic islets from extended high glucose exposure. We provide the Zofenoprilat Sodium Salt form.

Associated Targets

ACE Tclin Angiotensin-converting enzyme 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S,4S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid
INCHI InChI=1S/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12+,13+/m1/s1
InChi Key UQWLOWFDKAFKAP-WXHSDQCUSA-N
Canonical SMILES CC(CS)C(=O)N1CC(CC1C(=O)O)SC2=CC=CC=C2
Isomeric SMILES C[C@H](CS)C(=O)N1C[C@H](C[C@H]1C(=O)O)SC2=CC=CC=C2
PubChem CID 3034048
Molecular Weight 347.43

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO, water, and methanol.

Related Documents

Solution Calculators