| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Z650691-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $200.90 |
Phenylpropanoids Lignans
| Specifications & Purity | 99% |
|---|---|
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | (-)-Zuonin A (D-Epigalbacin), a naturally occurring lignin, is a potent, selective JNKs inhibitor, with IC 50 s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1 , JNK2 and JNK3 , respectively In Vitro (−)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs. (−)-zuonin A inhibits the activation and phosphorylation of JNK by MKK4 and MKK7. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:JNK1 1.7 μM (IC 50 ) JNK2 2.9 μM (IC 50 ) JNK3 1.74 μM (IC 50 ) |
| IUPAC Name | 5-[5-(1,3-benzodioxol-5-yl)-3,4-dimethyloxolan-2-yl]-1,3-benzodioxole |
|---|---|
| INCHI | InChI=1S/C20H20O5/c1-11-12(2)20(14-4-6-16-18(8-14)24-10-22-16)25-19(11)13-3-5-15-17(7-13)23-9-21-15/h3-8,11-12,19-20H,9-10H2,1-2H3 |
| InChi Key | QFUXQRHAJWXPGP-UHFFFAOYSA-N |
| Canonical SMILES | CC1C(C(OC1C2=CC3=C(C=C2)OCO3)C4=CC5=C(C=C4)OCO5)C |
| Isomeric SMILES | CC1C(C(OC1C2=CC3=C(C=C2)OCO3)C4=CC5=C(C=C4)OCO5)C |
| PubChem CID | 234441 |
| NSC Number | 34395 |
| Molecular Weight | 340.37 |
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| Solubility | DMSO : 100 mg/mL (293.80 mM; Need ultrasonic) |
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