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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T131784-250mg | 250mg | In stock | $13.90 | |
T131784-1g | 1g | In stock | $46.90 | |
T131784-5g | 5g | In stock | $210.90 | |
T131784-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
T131784-25g | 25g | In stock | $367.90 |
Synonyms | 1,2,3,4-Tetrahydro-beta-carboline | AKOS004119465 | THBC | 9H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro- | NC00329 | SpecPlus_000545 | BB 0260537 | KBio2_001055 | NCGC00018148-04 | Tox21_202753 | CAS-2257-09-2 | InChI=1/C11H12N2/c1-2-4-10-8(3-1)9-5-6-12-7-1 |
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Specifications & Purity | ≥96% |
Storage Temp | Protected from light |
Shipped In | Normal |
Product Description | Product Describtion: Ozonolysis of the enamine bond of 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole derivatives was studied. Product Application: Reactant for synthesis of the indolyl-β-carboline alkaloid eudistomin U via IBX mediated room temperature oxidative aromatization Reactant for preparation of neuroprotective HDAC6 inhibitors Reactant for preparation of aminofuranopyrimidines as EGFR and Aurora A kinase inhibitors Reactant for preparation of inhibitors of CDK4 Reactant for preparation of tetrahydrocarboline derivatives of as human 5-HT5A receptor ligands Reactant for preparation of 5-(diaminomethyl)-2,4-aminopyrimidines as dihydrofolate reductase inhibitors and antibacterial agents |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488187418 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488187418 |
IUPAC Name | 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole |
INCHI | InChI=1S/C11H12N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-4,12-13H,5-7H2 |
InChi Key | CFTOTSJVQRFXOF-UHFFFAOYSA-N |
Canonical SMILES | C1CNCC2=C1C3=CC=CC=C3N2 |
Isomeric SMILES | C1CNCC2=C1C3=CC=CC=C3N2 |
WGK Germany | 3 |
PubChem CID | 107838 |
Molecular Weight | 172.23 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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B2324878 | Certificate of Analysis | Dec 20, 2024 | T131784 |
B2324875 | Certificate of Analysis | Dec 20, 2024 | T131784 |
B2324874 | Certificate of Analysis | Dec 20, 2024 | T131784 |
B2324873 | Certificate of Analysis | Dec 20, 2024 | T131784 |
B2324871 | Certificate of Analysis | Dec 11, 2024 | T131784 |
B2324890 | Certificate of Analysis | Dec 11, 2024 | T131784 |
Sensitivity | light sensitive |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
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11. Minoru Tanaka,Xin Li,Hidemasa Hikawa,Takafumi Suzuki,Katsuhiko Tsutsumi,Masashi Sato,Osamu Takikawa,Hideharu Suzuki,Yuusaku Yokoyama. (2013-01-23) Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors.. Bioorganic & medicinal chemistry, 21 ((5)): (1159-1165). [PMID:23337802] |
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