1,2-dilauroyl-sn-glycero-3-phosphocholine - >99%, high purity , CAS No.18194-25-7

  • ≥99%
Item Number
D130415
Grouped product items
SKUSizeAvailabilityPrice Qty
D130415-25mg
25mg
In stock
$48.90
D130415-100mg
100mg
In stock
$127.90
D130415-500mg
500mg
In stock
$576.90

Phosphatidylcholine containing lauric acid

View related series
Lipid

Basic Description

SynonymsBDBM50467998 | IJFVSSZAOYLHEE-SSEXGKCCSA-N | 1,2-didodecanoyl-sn-phosphatidylcholine | A909168 | DLPC, R- | 1,2-didodeca-noyl-sn-glycero-3-phosphocholine | 1,2-Didodecanoyl-sn-glycero-3-phosphocholine | DLPC, L- | SCHEMBL44308 | (7R)-4-Hydroxy-N,N,N-trime
Specifications & Purity≥99%
Biochemical and Physiological MechanismsPhosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Product Introduction

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

12:0 PC (DLPC) is suitable to use as a phospholipid (PL) standard to quantify phosphatidylcholine (PC) by electrospray ionization mass spectrometry (ESI-MS).

Associated Targets(Human)

NR5A2 Tchem Nuclear receptor subfamily 5 group A member 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR5A2 Tchem Orphan nuclear receptor LRH-1 (736 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [(2R)-2,3-di(dodecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
INCHI InChI=1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m1/s1
InChi Key IJFVSSZAOYLHEE-SSEXGKCCSA-N
Canonical SMILES CCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC
Isomeric SMILES CCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC
WGK Germany 3
PubChem CID 512874
Molecular Weight 621.826
Beilstein 5676925

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
J2422280Certificate of AnalysisOct 25, 2024 D130415
D2423017Certificate of AnalysisFeb 13, 2023 D130415
E2210066Certificate of AnalysisFeb 13, 2023 D130415
E2210067Certificate of AnalysisFeb 13, 2023 D130415
D2312211Certificate of AnalysisFeb 06, 2023 D130415
E2306652Certificate of AnalysisFeb 06, 2023 D130415
K1922128Certificate of AnalysisFeb 06, 2023 D130415
F2122041Certificate of AnalysisJan 17, 2023 D130415
C2202210Certificate of AnalysisDec 13, 2022 D130415
F2328106Certificate of AnalysisMay 05, 2022 D130415

Chemical and Physical Properties

Solubility20mg/ml soluble in chloroform:methanol:acetic acid:water (100:30:10:2.5); slightly soluble in methanol.

Safety and Hazards(GHS)

WGK Germany 3

Related Documents

Citations of This Product

1. Yanzi Liang, Ruihuan Ding, Huihui Wang, Lanze Liu, Jibiao He, Yuping Tao, Zhenyu Zhao, Jie Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi.  (2022)  Orally administered intelligent self-ablating nanoparticles: a new approach to improve drug cellular uptake and intestinal absorption.  DRUG DELIVERY,  29  (1): (305-315).  [PMID:35037529] [10.1080/10717544.2021.2023704]
2. Hui Jiang, Hao Zhang, Shi-Jun Yin, Min Lu, Xu Wang, Feng-Qing Yang.  (2021)  Determination of lipid–water partition coefficient of neutral and ionic drugs by liposome electrokinetic chromatography.  ELECTROPHORESIS,  42  (14-15): (1436-1449).  [PMID:33908064] [10.1002/elps.202000382]
3. Xuejiao Zhang, Lei Lei, Haiyan Zhang, Siyu Zhang, Weiwei Xing, Jin Wang, Haibo Li, Qing Zhao, Baoshan Xing.  (2018)  Interactions of polymeric drug carriers with DDT reduce their combined cytotoxicity.  ENVIRONMENTAL POLLUTION,  241  (701).  [PMID:29902753] [10.1016/j.envpol.2018.06.010]

References

1. Yanzi Liang, Ruihuan Ding, Huihui Wang, Lanze Liu, Jibiao He, Yuping Tao, Zhenyu Zhao, Jie Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi.  (2022)  Orally administered intelligent self-ablating nanoparticles: a new approach to improve drug cellular uptake and intestinal absorption.  DRUG DELIVERY,  29  (1): (305-315).  [PMID:35037529] [10.1080/10717544.2021.2023704]
2. Hui Jiang, Hao Zhang, Shi-Jun Yin, Min Lu, Xu Wang, Feng-Qing Yang.  (2021)  Determination of lipid–water partition coefficient of neutral and ionic drugs by liposome electrokinetic chromatography.  ELECTROPHORESIS,  42  (14-15): (1436-1449).  [PMID:33908064] [10.1002/elps.202000382]
3. Xuejiao Zhang, Lei Lei, Haiyan Zhang, Siyu Zhang, Weiwei Xing, Jin Wang, Haibo Li, Qing Zhao, Baoshan Xing.  (2018)  Interactions of polymeric drug carriers with DDT reduce their combined cytotoxicity.  ENVIRONMENTAL POLLUTION,  241  (701).  [PMID:29902753] [10.1016/j.envpol.2018.06.010]

Solution Calculators