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SKU

Size

Availability

Price

Qty

N111090-1g

In stock

$18.90

N111090-5g

In stock

$81.90

N111090-25g

25g

Available within 4-8 weeks(?)

$365.90

N111090-100g

100g

In stock

$1,315.90

Basic Description

Synonyms	1,2-Naphthoquinone-4-sulfonic acid sodium salt \| AKOS003614484 \| Z57947969 \| N0043 \| .BETA.-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT \| 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM \| AI3-50008 \| EINECS 208-308-9 \| SB19104 \| 1,2-naphthoquinone-4-sulfonic aci
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Usually used in the colorimetric assay for determination of procaine hydrochloride in pharmaceutical preparations.

Associated Targets(Human)

PTPN1 Tchem Tyrosine-protein phosphatase non-receptor type 1 (0 Activities)

Discover Target: PTPN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	sodium;3,4-dioxonaphthalene-1-sulfonate
INCHI	InChI=1S/C10H6O5S.Na/c11-8-5-9(16(13,14)15)6-3-1-2-4-7(6)10(8)12;/h1-5H,(H,13,14,15);/q;+1/p-1
InChi Key	UBLXEEBHYISRFM-UHFFFAOYSA-M
Canonical SMILES	C1=CC=C2C(=C1)C(=CC(=O)C2=O)S(=O)(=O)[O-].[Na+]
Isomeric SMILES	C1=CC=C2C(=C1)C(=CC(=O)C2=O)S(=O)(=O)[O-].[Na+]
WGK Germany	3
RTECS	QK1490000
PubChem CID	516996
Molecular Weight	260.2
Beilstein	4169788
Reaxy-Rn	4169788

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
C2116226	Certificate of Analysis	Dec 09, 2024	N111090
C2116229	Certificate of Analysis	Dec 09, 2024	N111090
C2026093	Certificate of Analysis	Jan 18, 2024	N111090
B2302441	Certificate of Analysis	Jun 02, 2022	N111090
G2214265	Certificate of Analysis	Jun 02, 2022	N111090
G2214280	Certificate of Analysis	Jun 02, 2022	N111090
G2214281	Certificate of Analysis	Jun 02, 2022	N111090
I2420014	Certificate of Analysis	Jun 02, 2022	N111090
J2311071	Certificate of Analysis	Jun 02, 2022	N111090

Chemical and Physical Properties

Solubility	Soluble in water (~50 mg/ml), acetone (moderately), alcohol (slightly), and ethanol (slightly). Insoluble in chloroform.carbon disulfide: insoluble
Melt Point(°C)	289°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	QK1490000
Reaxy-Rn	4169788
Merck Index	8646

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Meng Du, Wei Chen, Chen Qian, Zhuo Chen, Guan-Lin Chen, Han-Qing Yu. (2023) Using Rayleigh Scattering to Correct the Inner Filter Effect of the Fluorescence Excitation–Emission Matrix. ANALYTICAL CHEMISTRY, 95 (33): (12273–12283). [PMID:37556363] [10.1021/acs.analchem.3c01093]
2. Bo Gong, Wei Chen, Patrick H.-L. Sit, Xian-Wei Liu, Chen Qian, Han-Qing Yu. (2023) Multiple spectroscopic insights into the interaction mechanisms between proteins and humic acid. WATER RESEARCH, 243 (120424). [PMID:37523922] [10.1016/j.watres.2023.120424]
3. Zhonghua Xue, Hui Wang, Honghong Rao, Nan He, Xiaofen Wang, Xiuhui Liu, Xiaoquan Lu. (2017) Amperometric indicator displacement assay for biomarker monitoring: Indirectly sensing strategy for electrochemically inactive sarcosine. TALANTA, 167 (666). [PMID:28340776] [10.1016/j.talanta.2017.03.009]

References

1. R B Salama,A I Omer. (1980-03-01) Colorimetric determination of procaine hydrochloride in pharmaceutical preparations.. Journal of pharmaceutical sciences, 69 ((3)): (346-348). [PMID:7381718]
2. D R Richardson,V Richardson. (1998-05-30) The effect of impermeable oxidants on the growth of neoplastic cells.. In vitro cellular & developmental biology. Animal, 34 ((1)): (30-34). [PMID:9542632]
3. P Nagaraja,K C Murthy,K S Rangappa. (1998-07-10) Spectrophotometric method for the determination of paracetamol and phenacetin.. Journal of pharmaceutical and biomedical analysis, 17 ((3)): (501-506). [PMID:9656162]
4. D Hernando,J Saurina,S Hernández-Cassou. (1999-11-26) Liquid chromatographic determination of aniline in table-top sweeteners based on pre-column derivatization with 1,2-naphthoquinone-4-sulfonate.. Journal of chromatography. A, 859 ((2)): (227-233). [PMID:10574215]
5. R M Latorre,S Hernández-Cassou,J Saurina. (2002-01-05) Strategies for in-capillary derivatization of amino acids in capillary electrophoresis using 1,2-naphthoquinone-4-sulfonate as a labeling reagent.. Journal of chromatography. A, 934 ((1-2)): (105-112). [PMID:11762757]
6. Huai You Wang,Li Xiao Xu,Yan Xiao,Juan Han. (2004-09-08) Spectrophotometric determination of dapsone in pharmaceutical products using sodium 1,2-naphthoquinone-4-sulfonic as the chromogenic reagent.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60 ((12)): (2933-2939). [PMID:15350932]
7. Lixiao Xu,Huaiyou Wang,Yan Xiao. (2004-10-13) Spectrophotometric determination of ampicillin sodium in pharmaceutical products using sodium 1,2-naphthoquinone-4-sulfonic as the chromogentic reagent.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60 ((13)): (3007-3012). [PMID:15477137]
8. Y Moliner-Martínez,P Campíns-Falcó,R Herráez-Hernández. (2005-01-05) A method for the determination of dimethylamine in air by collection on solid support sorbent with subsequent derivatization and spectrophotometric analysis.. Journal of chromatography. A, 1059 ((1-2)): (17-24). [PMID:15628120]
9. Leah Hlabangana,Santiago Hernández-Cassou,Javier Saurina. (2006-07-04) Determination of biogenic amines in wines by ion-pair liquid chromatography and post-column derivatization with 1,2-naphthoquinone-4-sulphonate.. Journal of chromatography. A, 1130 ((1)): (130-136). [PMID:16814303]
10. Quanmin Li,Tiantian Zhang. (2006-09-09) Study of the sensitization of tetradecyl benzyl dimethyl ammonium chloride for the color development reaction between lysine and sodium 1,2-naphthoquinone-4-sulfonate and the determination of lysine in pharmaceutical and biological samples.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67 ((2)): (360-367). [PMID:16959536]
11. Quan-Min Li,Zhan-Jun Yang. (2006-11-18) Spectrophotometric determination of aminomethylbenzoic acid using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 66 ((3)): (656-661). [PMID:17110157]
12. Masoumeh Hasani,Leila Yaghoubi,Hamid Abdollahi. (2007-03-22) A kinetic spectrophotometric method for simultaneous determination of glycine and lysine by artificial neural networks.. Analytical biochemistry, 365 ((1)): (74-81). [PMID:17374354]
13. Linxiao Gao,Lingli Wu,Quanmin Li. (2008-09-16) Catalysis reaction between sodium 1,2-naphthoquinone-4-sulfonate and hydroxyl ion using captopril as catalyzer and determination of captopril.. Analytica chimica acta, 626 ((2)): (174-179). [PMID:18790118]
14. Ibrahim A Darwish,Heba H Abdine,Sawsan M Amer,Lama I Al-Rayes. (2009-01-13) Spectrophotometric study for the reaction between fluvoxamine and 1,2-naphthoquinone-4-sulphonate: Kinetic, mechanism and use for determination of fluvoxamine in its dosage forms.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72 ((4)): (897-902). [PMID:19135409]
15. Sameer A M Abdulrahman,Kanakapura Basavaiah. (2011-02-22) Sensitive and selective spectrophotometric assay of gabapentin in capsules using sodium 1, 2-naphthoquinone-4-sulfonate.. Drug testing and analysis, 3 ((10)): (748-754). [PMID:21337720]
16. L A Levchenko,A P Sadkov,S A Marakushev,N V Lariontseva. (1997-01-01) Participation of biological membranes in colloidal gold transformation by Micrococcus luteus cells.. Membrane & cell biology, 11 ((1)): (131-135). [PMID:9257288]
17. J A Kiernan,C M Macpherson,A Price,T Sun. (1998-11-26) A histochemical examination of the staining of kainate-induced neuronal degeneration by anionic dyes.. Biotechnic & histochemistry : official publication of the Biological Stain Commission, 73 ((5)): (244-254). [PMID:9829417]
18. L G Martinez,P Campíns-Falcó,A Sevillano-Cabeza,F Bosch-Reig. (1998-12-01) New spectrophotometric procedure for determining cefotaxime based on derivatization with 1,2-naphthoquinone-4-sulphonate into solid-phase extraction cartridges--application to pharmaceutical and urine samples.. Journal of chromatography. B, Biomedical sciences and applications, 718 ((1)): (143-151). [PMID:9832371]
19. R M Latorre,J Saurina,S Hernández-Cassou. (2000-03-22) Resolution of overlapped peaks of amino acid derivatives in capillary electrophoresis using multivariate curve resolution based on alternating least squares.. Electrophoresis, 21 ((3)): (563-572). [PMID:10726761]
20. Li Xiao Xu,Yun Xiu Shen,Huai You Wang,Ji Gang Jiang,Yan Xiao. (2003-10-30) Spectrophotometric determination of procaine hydrochloride in pharmaceutical products using 1,2-naphthoquinone-4-sulfonic acid as the chromogenic reagent.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59 ((13)): (3103-3110). [PMID:14583285]
21. Natividad García-Villar,Javier Saurina,Santiago Hernández-Cassou. (2005-12-07) Capillary electrophoresis determination of biogenic amines by field-amplified sample stacking and in-capillary derivatization.. Electrophoresis, 27 ((2)): (474-483). [PMID:16331588]
22. Quanmin Li,Juan Li,Zhanjun Yang. (2007-03-28) Study of the sensitization of tetradecyl benzyl dimethyl ammonium chloride for spectrophotometric determination of dopamine hydrochloride using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent.. Analytica chimica acta, 583 ((1)): (147-152). [PMID:17386539]
23. Natividad García-Villar,Santiago Hernández-Cassou,Javier Saurina. (2009-08-01) Determination of biogenic amines in wines by pre-column derivatization and high-performance liquid chromatography coupled to mass spectrometry.. Journal of chromatography. A, 1216 ((36)): (6387-6393). [PMID:19643426]
24. Santiago Hernández-Cassou,Javier Saurina. (2010-12-28) Derivatization strategies for the determination of biogenic amines in wines by chromatographic and electrophoretic techniques.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879 ((17-18)): (1270-1281). [PMID:21185242]
25. Linjin Ma,Zhenxuan Zhang,Quanmin Li. (2011-05-03) Spectrophotometric determination of boron based on charge transfer reaction.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79 ((3)): (599-602). [PMID:21530377]
26. Ayman A Gouda,Hisham Hashem,Wafaa Hassan. (2011-05-04) Spectophotometric methods for determination of cefdinir in pharmaceutical formulations via derivatization with 1,2-naphthoquinone-4-sulfonate and 4-chloro-7-nitrobenzo-2-oxa-1, 3-diazole.. Drug testing and analysis, 4 ((12)): (991-1000). [PMID:21538942]
27. Shuguang Cao. (2023) Synergistic effect of multifunctional MXene-nanosheet and naphthoquinone sulfonate toward high-performance perovskite solar cells and modules. Chemical Engineering Journal, 2023 (474): (145707). [PMID:] [https://doi.org/10.1016/j.cej.2023.145707]
28. Meng Du, Wei Chen, Chen Qian, Zhuo Chen, Guan-Lin Chen, Han-Qing Yu. (2023) Using Rayleigh Scattering to Correct the Inner Filter Effect of the Fluorescence Excitation–Emission Matrix. ANALYTICAL CHEMISTRY, 95 (33): (12273–12283). [PMID:37556363] [10.1021/acs.analchem.3c01093]
29. Bo Gong, Wei Chen, Patrick H.-L. Sit, Xian-Wei Liu, Chen Qian, Han-Qing Yu. (2023) Multiple spectroscopic insights into the interaction mechanisms between proteins and humic acid. WATER RESEARCH, 243 (120424). [PMID:37523922] [10.1016/j.watres.2023.120424]
30. Zhonghua Xue, Hui Wang, Honghong Rao, Nan He, Xiaofen Wang, Xiuhui Liu, Xiaoquan Lu. (2017) Amperometric indicator displacement assay for biomarker monitoring: Indirectly sensing strategy for electrochemically inactive sarcosine. TALANTA, 167 (666). [PMID:28340776] [10.1016/j.talanta.2017.03.009]

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1,2-Naphthoquinone-4-sulfonic acid sodium salt - 98%, high purity , CAS No.521-24-4

Basic Description

Associated Targets(Human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator