Basic Description

Synonyms	1-(Pyridin-2-azo)-2-naphthol \| NCGC00247231-01 \| 1-(Pyridin-2-yldiazenyl)naphthalen-2-ol \| HMS2310J23 \| 1-(2-Pyridylazo)-2-naphthol, for spectrophotometric det. of metal ions, >=97.0% \| PAN (indicator) \| EINECS 201-637-9 \| 095B53Y3XV \| (E)-1-(pyridin-2-yl
Specifications & Purity	metal indicator, Ph.Eur.
Storage Temp	Room temperature
Shipped In	Normal
Grade	metal indicator, Ph.Eur.

Associated Targets(Human)

POLB Tchem DNA polymerase beta (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CBX1 Tbio Chromobox protein homolog 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GMNN Tbio Geminin (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLH Tchem DNA polymerase eta (0 Activities)

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RORC Tchem Nuclear receptor ROR-gamma (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSP90AA1 Tchem Heat shock protein HSP 90-alpha (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FTL Tbio Ferritin light chain (0 Activities)

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FEN1 Tchem Flap endonuclease 1 (0 Activities)

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HSF1 Tchem Heat shock factor protein 1 (0 Activities)

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SMN1 Tchem Survival motor neuron protein (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX12 Tchem Arachidonate 12-lipoxygenase, 12S-type (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LMNA Tbio Prelamin-A/C (0 Activities)

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MBNL1 Tbio Muscleblind-like protein 1 (0 Activities)

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BRCA1 Tchem Breast cancer type 1 susceptibility protein (0 Activities)

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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATXN2 Tbio Ataxin-2 (0 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

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GNAS Tbio Protein ALEX (0 Activities)

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ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)

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MAPT Tclin Microtubule-associated protein tau (0 Activities)

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ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTT Tchem Huntingtin (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IMPA1 Tclin Inositol monophosphatase 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CGA Tbio Glycoprotein hormones alpha chain (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor (0 Activities)

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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NPSR1 Tchem Neuropeptide S receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4A Tchem Lysine-specific demethylase 4A (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NPC1 Tchem NPC intracellular cholesterol transporter 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa opioid receptor (16155 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLB Tchem DNA polymerase beta (23632 Activities)

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GLB1 Tchem Beta-galactosidase (339 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSP90AA1 Tchem Heat shock protein HSP 90-alpha (4115 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEK293 (82097 Activities)

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FEN1 Tchem Flap endonuclease 1 (12055 Activities)

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GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLH Tchem DNA polymerase eta (21678 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTT Tchem Huntingtin (19182 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)

Discover Target: BRCA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)

Discover Target: L3MBTL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMN1 Tchem Survival motor neuron protein (34246 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NPC1 Tchem Niemann-Pick C1 protein (18985 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATXN2 Tbio Ataxin-2 (54410 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CGA Tbio Glycoprotein hormones alpha chain (29278 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

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INS1 (2867 Activities)

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Npsr1 Neuropeptide S receptor (260 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hsf1 Heat shock factor protein 1 (5445 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

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Mapt Microtubule-associated protein tau (6 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Impa1 Inositol monophosphatase 1 (16203 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NS1 Nonstructural protein 1 (33327 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSP90 (947 Activities)

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LMP1 Latent membrane protein 1 (726 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

recD Exodeoxyribonuclease V (225 Activities)

Discover Target: recD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-(pyridin-2-yldiazenyl)naphthalen-2-ol
INCHI	InChI=1S/C15H11N3O/c19-13-9-8-11-5-1-2-6-12(11)15(13)18-17-14-7-3-4-10-16-14/h1-10,19H
InChi Key	LLYOXZQVOKALCD-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C2C(=C1)C=CC(=C2N=NC3=CC=CC=N3)O
Isomeric SMILES	C1=CC=C2C(=C1)C=CC(=C2N=NC3=CC=CC=N3)O
WGK Germany	3
PubChem CID	6825
Molecular Weight	249.27

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)	138-141°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P264:Wash hands [and …] thoroughly after handling. P337+P313:IF eye irritation persists: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
WGK Germany	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Lei Jin, Zhao-Yun Wang, Zhuan-Yun Cai, Jia-Qiang Yang, An-Ni Zheng, Fang-Zu Yang, De-Yin Wu, Dongping Zhan. (2023) 1-(2-Pyridylazo)-2-naphthol as a synergistic additive for improving throwing power of through hole copper electronic electroplating. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 125 (269). [PMID:] [10.1016/j.jiec.2023.05.036]
2. Yong Han, Weixia Yang, Xueli Luo, Xie He, Ying Yu, Chunhua Li, Wenzhi Tang, Tianli Yue, Zhonghong Li. (2019) Cu2+-Triggered Carbon Dots with Synchronous Response of Dual Emission for Ultrasensitive Ratiometric Fluorescence Determination of Thiophanate-Methyl Residues. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (45): (12576–12583). [PMID:31618026] [10.1021/acs.jafc.9b04720]
3. Zhonghua Xue, Lulu Xiong, Hao Peng, Honghong Rao, Xiuhui Liu, Xiaoquan Lu. (2018) A selective colorimetric sensing strategy for cysteine based on an indicator-displacement mechanism. NEW JOURNAL OF CHEMISTRY, 42 (6): (4324-4330). [PMID:] [10.1039/C7NJ03887A]
4. Yang Hu, Lihui Wang, Jie Shen, Guoqiang Jiang, Chengyou Kan. (2018) Preparation and characterization of porous cationic poly[styrene-co-(N,N′-dimethylaminoethyl methacrylate)] nanoparticles and their adsorption of heavy metal ions in water. POLYMER INTERNATIONAL, 67 (5): (535-543). [PMID:] [10.1002/pi.5541]
5. Fan Chunlei, Pan Qinhe, Li Qun, Wang Liyuan. (2016) Cloud point-TiO2/sepiolite composites extraction for simultaneous preconcentration and determination of nickel in green tea and coconut water. Journal of the Iranian Chemical Society, 13 (2): (331-337). [PMID:] [10.1007/s13738-015-0741-6]
6. Iqbal Jibran, Yin Changhai, Geng Jinpei, Li Xiaoyu, Li Xiuyong, Du Yiping, Liu Bing Xiang. (2012) Ultra-sensitive spectrophotometric determination of nickel after complexation and membrane filtration. MICROCHIMICA ACTA, 177 (1): (195-200). [PMID:] [10.1007/s00604-012-0778-5]

References

1. Lei Jin, Zhao-Yun Wang, Zhuan-Yun Cai, Jia-Qiang Yang, An-Ni Zheng, Fang-Zu Yang, De-Yin Wu, Dongping Zhan. (2023) 1-(2-Pyridylazo)-2-naphthol as a synergistic additive for improving throwing power of through hole copper electronic electroplating. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 125 (269). [PMID:] [10.1016/j.jiec.2023.05.036]
2. Yong Han, Weixia Yang, Xueli Luo, Xie He, Ying Yu, Chunhua Li, Wenzhi Tang, Tianli Yue, Zhonghong Li. (2019) Cu2+-Triggered Carbon Dots with Synchronous Response of Dual Emission for Ultrasensitive Ratiometric Fluorescence Determination of Thiophanate-Methyl Residues. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (45): (12576–12583). [PMID:31618026] [10.1021/acs.jafc.9b04720]
3. Zhonghua Xue, Lulu Xiong, Hao Peng, Honghong Rao, Xiuhui Liu, Xiaoquan Lu. (2018) A selective colorimetric sensing strategy for cysteine based on an indicator-displacement mechanism. NEW JOURNAL OF CHEMISTRY, 42 (6): (4324-4330). [PMID:] [10.1039/C7NJ03887A]
4. Yang Hu, Lihui Wang, Jie Shen, Guoqiang Jiang, Chengyou Kan. (2018) Preparation and characterization of porous cationic poly[styrene-co-(N,N′-dimethylaminoethyl methacrylate)] nanoparticles and their adsorption of heavy metal ions in water. POLYMER INTERNATIONAL, 67 (5): (535-543). [PMID:] [10.1002/pi.5541]
5. Fan Chunlei, Pan Qinhe, Li Qun, Wang Liyuan. (2016) Cloud point-TiO2/sepiolite composites extraction for simultaneous preconcentration and determination of nickel in green tea and coconut water. Journal of the Iranian Chemical Society, 13 (2): (331-337). [PMID:] [10.1007/s13738-015-0741-6]
6. Iqbal Jibran, Yin Changhai, Geng Jinpei, Li Xiaoyu, Li Xiuyong, Du Yiping, Liu Bing Xiang. (2012) Ultra-sensitive spectrophotometric determination of nickel after complexation and membrane filtration. MICROCHIMICA ACTA, 177 (1): (195-200). [PMID:] [10.1007/s00604-012-0778-5]

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1-(2-Pyridylazo)-2-naphthol (PAN) - metal indicator Reag. Ph Eur, high purity , CAS No.85-85-8

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator