Basic Description

Synonyms	1,3-Bis(4-carboxyphenoxy)propane \| 3753-81-9 \| 1,3-Bis-cpp \| 4-[3-(4-carboxyphenoxy)propoxy]benzoic acid \| 1,3-Bis(p-carboxyphenoxy)propane \| 1XMW35DTHB \| 4,4'-(1,3-Propanediylbis(oxy))bis-benzoic acid \| DTXSID8046585 \| 4,4'-[propane-1,3-diylbis(oxy)]dibenzoic acid \| 1,3-b
Specifications & Purity	≥97%
Product Description	Description Building block for polyanhydrides, a class of bioerodible polymer with drug delivery applications.

Associated Targets(Human)

PMP22 Tbio Peripheral myelin protein 22 (0 Activities)

Discover Target: PMP22

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

Discover Target: PMP22

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mycobacterium tuberculosis (203094 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	4-[3-(4-carboxyphenoxy)propoxy]benzoic acid
INCHI	InChI=1S/C17H16O6/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H,18,19)(H,20,21)
InChi Key	VBISQLWPGDULSX-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1C(=O)O)OCCCOC2=CC=C(C=C2)C(=O)O
Isomeric SMILES	C1=CC(=CC=C1C(=O)O)OCCCOC2=CC=C(C=C2)C(=O)O
WGK Germany	3
PubChem CID	68610
Molecular Weight	316.31

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Hazard Statements	H317:May cause an allergic skin reaction H400:Very toxic to aquatic life
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection.
WGK Germany	3
RIDADR	UN30779/PGIII

References

1. A J Domb,M Rock,J Schwartz,C Perkin,G Yipchuk,B Broxup,J G Villemure. (1994-07-01) Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain.. Biomaterials, 15 ((9)): (681-688). [PMID:7948590]
2. Matt J Kipper, Elizabeth Shen, Amy Determan, Balaji Narasimhan,. (2002-09-11) Design of an injectable system based on bioerodible polyanhydride microspheres for sustained drug delivery.. Biomaterials, 23 ((22)): ( 4405-4412 ). [PMID:12219831]
3. Aijun Zhao,Tao Chen,Qi Zhou,Shaobing Zhou. (2011-12-27) One type of novel thermosensitive polymeric micelles.. Journal of controlled release : official journal of the Controlled Release Society, 152 Suppl 1 (e127-e128). [PMID:22195797]
4. Minze Zhu,Andrew K Whittaker,Xingyu Jiang,Rupei Tang,Xuanyu Li,Weizhi Xu,Changkui Fu,Maree T Smith,Felicity Y Han. (2020-10-04) Use of Microfluidics to Fabricate Bioerodable Lipid Hybrid Nanoparticles Containing Hydromorphone or Ketamine for the Relief of Intractable Pain.. Pharmaceutical research, 37 ((10)): (211-211). [PMID:33009588]
5. A J Domb,M Rock,C Perkin,G Yipchuck,B Broxup,J G Villemure. (1995-09-01) Excretion of a radiolabelled anticancer biodegradable polymeric implant from the rabbit brain.. Biomaterials, 16 ((14)): (1069-1072). [PMID:8519927]
6. Moon Suk Kim,Kwang Su Seo,Ha Soo Seong,Sun Hang Cho,Hai Bang Lee,Keum Duck Hong,Sun Kyung Kim,Gilson Khang. (2005-05-25) Synthesis and characterization of polyanhydride for local BCNU delivery carriers.. Bio-medical materials and engineering, 15 ((3)): (229-238). [PMID:15912003]
7. Sijian Hou,Laurie K McCauley,Peter X Ma. (2007-04-26) Synthesis and erosion properties of PEG-containing polyanhydrides.. Macromolecular bioscience, 7 ((5)): (620-628). [PMID:17457940]
8. Xiaohua Liu,Glenda J Pettway,Laurie K McCauley,Peter X Ma. (2007-06-20) Pulsatile release of parathyroid hormone from an implantable delivery system.. Biomaterials, 28 ((28)): (4124-4131). [PMID:17576005]

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1,3-Bis(4-carboxyphenoxy)propane - 97%, high purity , CAS No.3753-81-9