Grouped product items

SKU

Size

Availability

Price

Qty

C106972-25g

25g

In stock

$19.90

C106972-100g

100g

Available within 4-8 weeks(?)

$68.90

C106972-500g

500g

Available within 4-8 weeks(?)

$307.90

Basic Description

Synonyms	F0001-1313 \| Hydroresorcinol \| NSC57477 \| NSC-57477 \| EC 207-980-0 \| 6UK3D2BXJT \| STL145900 \| UNII-6UK3D2BXJT \| BDBM22770 \| AM20070493 \| DTXCID9024433 \| EINECS 207-980-0 \| Tox21_302158 \| cyclohexan- 1,3-dione \| AI3-11062 \| PB42931 \| AKOS000119320 \| cycloh
Specifications & Purity	≥97%
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCHE Tclin Butyrylcholinesterase (7174 Activities)

Discover Target: BCHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CES2 Tchem Carboxylesterase 2 (583 Activities)

Discover Target: CES2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CES1 Tchem Acyl coenzyme A:cholesterol acyltransferase (1029 Activities)

Discover Target: CES1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488181135
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488181135
IUPAC Name	cyclohexane-1,3-dione
INCHI	InChI=1S/C6H8O2/c7-5-2-1-3-6(8)4-5/h1-4H2
InChi Key	HJSLFCCWAKVHIW-UHFFFAOYSA-N
Canonical SMILES	C1CC(=O)CC(=O)C1
Isomeric SMILES	C1CC(=O)CC(=O)C1
WGK Germany	3
RTECS	GV0350000
PubChem CID	10434
Molecular Weight	112.13
Beilstein	385888
Reaxy-Rn	385888

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
H2408319	Certificate of Analysis	Apr 02, 2024	C106972
G2425162	Certificate of Analysis	Apr 02, 2024	C106972
G2425163	Certificate of Analysis	Apr 02, 2024	C106972
F2314822	Certificate of Analysis	Jun 03, 2023	C106972
F2314832	Certificate of Analysis	Jun 03, 2023	C106972
F2314917	Certificate of Analysis	Jun 03, 2023	C106972
L2220151	Certificate of Analysis	Dec 27, 2022	C106972

Chemical and Physical Properties

Solubility	Soluble in water (155 g/L) at 20°C, alcohol, chloroform, acetone, boiling benzene, ether (slightly), carbon disulfide (slightly), and petr ether (slightly).
Sensitivity	Heat & Air & Light Sensitive
Melt Point(°C)	101-105°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H318:Causes serious eye damage
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help.
WGK Germany	3
RTECS	GV0350000
Reaxy-Rn	385888
Merck Index	3178

FAQs and Articles

FAQ

Aldol Condensation Reaction

Categories: Technical articles

Tags:

Organic block Building Blocks Catalytic agent Inorganic catalyst Aldol condensation reaction

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Zhongqiu Liu, Yuanyuan Yu, Shengnan Li, Yaqi Liu, Guoqiang Zhang, Long Han, Yujing Liu, Jinmao You, Anguo Ying. (2021) Collaborative fabrication of poly(L-proline)s with well-defined mesopores and hydrophobicity: Synergistic effect of mesoporous confinement and hydrophobic micro-environment on organic transformations. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 104 (592). [PMID:] [10.1016/j.jiec.2021.09.006]
2. Liu Yaqing, Lin Xiaodong, Ji Xiangyi, Hao Zhe, Tao Zhanhui. (2020) Smartphone-based enzyme-free fluorescence sensing of organophosphate DDVP. MICROCHIMICA ACTA, 187 (7): (1-8). [PMID:32613298] [10.1007/s00604-020-04384-7]
3. Ming-Yu Wu, Kun Li, Ting He, Xing-Wen Feng, Na Wang, Xiao-Yan Wang, Xiao-Qi Yu. (2011) A novel enzymatic tandem process: utilization of biocatalytic promiscuity for high stereoselective synthesis of 5-hydroxyimino-4,5-dihydrofurans. TETRAHEDRON, 67 (2681). [PMID:] [10.1016/j.tet.2011.01.060]

References

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2. A E Holley,M K Walker,K H Cheeseman,T F Slater. (1993-09-01) Measurement of n-alkanals and hydroxyalkenals in biological samples.. Free radical biology & medicine, 15 ((3)): (281-289). [PMID:8406128]
3. S Ishimitsu,A Kaihara,K Yoshii,Y Tsumura,Y Nakamura,Y Tonogai. (2001-08-15) Determination of clethodim and its oxidation metabolites in crops by liquid chromatography with confirmation by LC/MS.. Journal of AOAC International, 84 ((4)): (1172-1178). [PMID:11501920]
4. Ralph W Howard,James E Baker. (2004-06-15) Stage-specific surface chemicals of Plodia interpunctella: 2-acyl-1,3-cyclohexanediones from larval mandibular glands serve as cuticular lipids.. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 138 ((2)): (193-206). [PMID:15193275]
5. Tae-Joon Kim,Jin-Seog Kim,Kyoung Sik Hong,In-Taek Hwang,Kyoung Mahn Kim,Hyeong-Rae Kim,Kwang Yun Cho. (2004-09-24) EK-2612, a new cyclohexane-1,3-dione possessing selectivity between rice (Oryza sativa) and barnyardgrass (Echinochloa crus-galli).. Pest management science, 60 ((9)): (909-913). [PMID:15382506]
6. Randy M Wadkins,Janice L Hyatt,Xin Wei,Kyoung Jin P Yoon,Monika Wierdl,Carol C Edwards,Christopher L Morton,John C Obenauer,Komath Damodaran,Paul Beroza,Mary K Danks,Philip M Potter. (2005-04-15) Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.. Journal of medicinal chemistry, 48 ((8)): (2906-2915). [PMID:15828829]
7. Michael L Neidig,Andrea Decker,Michael Kavana,Graham R Moran,Edward I Solomon. (2005-10-04) Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: active site contributions to drug inhibition.. Biochemical and biophysical research communications, 338 ((1)): (206-214). [PMID:16197918]
8. Reiko Fujita,Masato Hoshino,Yusuke Tojyo,Atsushi Kimura,Hiroshi Hongo. (2006-02-08) [Reaction of pyridinium and quinolinium salts having the leaving group at the 2- or 4-position with active methylene compounds].. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 126 ((2)): (99-108). [PMID:16462099]
9. Guan-Wu Wang,Ya-Wei Dong,Ping Wu,Ting-Ting Yuan,Ye-Bing Shen. (2008-08-20) Unexpected solvent-free cycloadditions of 1,3-cyclohexanediones to 1-(pyridin-2-yl)-enones mediated by manganese(III) acetate in a ball mill.. The Journal of organic chemistry, 73 ((18)): (7088-7095). [PMID:18710288]
10. Anthony Adeuya,Neil P J Price. (2009-03-18) Electron impact ion fragmentation pathways of peracetylated C-glycoside ketones derived from cyclic 1,3-diketones.. Rapid communications in mass spectrometry : RCM, 23 ((8)): (1173-1182). [PMID:19291692]
11. Kerstin Rohr,Rainer Mahrwald. (2009-03-31) Catalyst-free tandem aldol condensation/Michael addition of 1,3-cyclohexanediones with enolizable aldehydes.. Bioorganic & medicinal chemistry letters, 19 ((14)): (3949-3951). [PMID:19328691]
12. Xiao-Qing Zhao,Zhi-Qi Zhang. (2009-09-29) Microwave-assisted on-line derivatization for sensitive flow injection fluorometric determination of formaldehyde in some foods.. Talanta, 80 ((1)): (242-245). [PMID:19782221]
13. Ramin Ghahremanzadeh,Fatemeh Fereshtehnejad,Ayoob Bazgir. (2010-04-23) Chromeno[2,3-d]pyrimidine-triones synthesis by a three-component coupling reaction.. Chemical & pharmaceutical bulletin, 58 ((4)): (516-520). [PMID:20410635]
14. Kou Hiroya,Yoshihiro Suwa,Yusuke Ichihashi,Kiyofumi Inamoto,Takayuki Doi. (2011-05-06) Total synthesis of optically active lycopladine A by utilizing diastereoselective protection of carbonyl group in a 1,3-cyclohexanedione derivative.. The Journal of organic chemistry, 76 ((11)): (4522-4532). [PMID:21542635]
15. Rema B Devi,Matthias Henrot,Michaël De Paolis,Jacques Maddaluno. (2011-08-10) Domino alkylation/oxa-Michael of 1,3-cyclohexanediones: steering the C/O-chemoselectivity to reach tetrahydrobenzofuranones.. Organic & biomolecular chemistry, 9 ((19)): (6509-6512). [PMID:21826296]
16. K P Braun,R B Cody,D R Jones,C M Peterson. (1995-05-12) A structural assignment for a stable acetaldehyde-lysine adduct.. The Journal of biological chemistry, 270 ((19)): (11263-11266). [PMID:7744761]
17. S R Webb,J C Hall. (2001-03-10) Polyclonal-based ELISA for the identification of cyclohexanedione analogs that inhibit maize acetyl coenzyme-A carboxylase.. Journal of AOAC International, 84 ((1)): (143-149). [PMID:11234801]
18. M T Zanni,N H Ge,Y S Kim,R M Hochstrasser. (2001-09-20) Two-dimensional IR spectroscopy can be designed to eliminate the diagonal peaks and expose only the crosspeaks needed for structure determination.. Proceedings of the National Academy of Sciences of the United States of America, 98 ((20)): (11265-11270). [PMID:11562493]
19. Sergey A Yermolayev,Nikolay Yu Gorobets,Sergey M Desenko. (2008-12-09) Rapid three-step one-pot microwave-assisted synthesis of 2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarbonitrile library.. Journal of combinatorial chemistry, 11 ((1)): (44-46). [PMID:19061393]
20. Sergey Molchanov,Adam Gryff-Keller. (2009-07-22) Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione.. Acta biochimica Polonica, 56 ((3)): (447-454). [PMID:19621095]
21. Theola Louie,C Dean Goodman,Georgina A Holloway,Geoffrey I McFadden,Vanessa Mollard,Keith G Watson. (2010-06-29) Dimeric cyclohexane-1,3-dione oximes inhibit wheat acetyl-CoA carboxylase and show anti-malarial activity.. Bioorganic & medicinal chemistry letters, 20 ((15)): (4611-4613). [PMID:20580556]
22. Chimène Asta,Dietmar Schmidt,Jürgen Conrad,Wolfgang Frey,Uwe Beifuss. (2013-07-26) Combination of enzyme- and Lewis acid-catalyzed reactions: a new method for the synthesis of 6,7-dihydrobenzofuran-4(5H)-ones starting from 2,5-dimethylfuran and 1,3-cyclohexanediones.. Organic & biomolecular chemistry, 11 ((34)): (5692-5701). [PMID:23884357]
23. Zhongqiu Liu, Yuanyuan Yu, Shengnan Li, Yaqi Liu, Guoqiang Zhang, Long Han, Yujing Liu, Jinmao You, Anguo Ying. (2021) Collaborative fabrication of poly(L-proline)s with well-defined mesopores and hydrophobicity: Synergistic effect of mesoporous confinement and hydrophobic micro-environment on organic transformations. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 104 (592). [PMID:] [10.1016/j.jiec.2021.09.006]
24. Liu Yaqing, Lin Xiaodong, Ji Xiangyi, Hao Zhe, Tao Zhanhui. (2020) Smartphone-based enzyme-free fluorescence sensing of organophosphate DDVP. MICROCHIMICA ACTA, 187 (7): (1-8). [PMID:32613298] [10.1007/s00604-020-04384-7]
25. Ming-Yu Wu, Kun Li, Ting He, Xing-Wen Feng, Na Wang, Xiao-Yan Wang, Xiao-Qi Yu. (2011) A novel enzymatic tandem process: utilization of biocatalytic promiscuity for high stereoselective synthesis of 5-hydroxyimino-4,5-dihydrofurans. TETRAHEDRON, 67 (2681). [PMID:] [10.1016/j.tet.2011.01.060]

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1,3-Cyclohexanedione - 97%, high purity , CAS No.504-02-9