1,4-DPCA - 98%, high purity , CAS No.331830-20-7

Item Number

D340140

Grouped product items
SKU	Size	Availability	Price
D340140-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$19.90
D340140-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$43.90
D340140-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$72.90
D340140-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$149.90
D340140-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$239.90
D340140-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
D340140-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$879.90

a selective and potent inhibitor of P4HA (α-prolyl 4-hydroxylase)

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Basic Description

Synonyms	1,4-DPCA\|331830-20-7\|53946-49-9\|4-oxo-1H-1,10-phenanthroline-3-carboxylic acid\|4-Oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylic acid\|CHEMBL4475458\|AC1LA18U\|SCHEMBL703592\|SCHEMBL13225925\|DTXSID90332701\|HMS3649E16\|BDBM50510129\|PD127748\|3-Acetyl-1H-[1,10]p
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	1,4 DPCA is a selective and potent inhibitor of prolyl 4-hydroxylation (P4H)\|in vitro\|. It has been shown to Inhibit α-prolyl 4-hydroxylase, an oxygen-sensing enzyme that targets the pro-angiogenic factor HIF-1α for destruction upon hydroxylation of a specific proline residue. 1,4-DPCA has also been shown to inhibit asparaginyl-hydroxylase factor inhibiting HIF (FIH) and to be useful for controlling excess collagen deposition in pathological fibrosis.

Names and Identifiers

IUPAC Name	4-oxo-1H-1,10-phenanthroline-3-carboxylic acid
INCHI	InChI=1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18)
InChi Key	XZZHOJONZJQARN-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C3=C(C=C2)C(=O)C(=CN3)C(=O)O)N=C1
Isomeric SMILES	C1=CC2=C(C3=C(C=C2)C(=O)C(=CN3)C(=O)O)N=C1
PubChem CID	459803
Molecular Weight	240.21

Certificates

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13 results found

Lot Number	Certificate Type	Date	Item
F2426570	Certificate of Analysis	Mar 18, 2024	D340140
F2426582	Certificate of Analysis	Mar 18, 2024	D340140
F2426583	Certificate of Analysis	Mar 18, 2024	D340140
F2426584	Certificate of Analysis	Mar 18, 2024	D340140
F2426585	Certificate of Analysis	Mar 18, 2024	D340140
F2426586	Certificate of Analysis	Mar 18, 2024	D340140
F2426587	Certificate of Analysis	Mar 18, 2024	D340140
F2426588	Certificate of Analysis	Mar 18, 2024	D340140
F2426589	Certificate of Analysis	Mar 18, 2024	D340140
F2426590	Certificate of Analysis	Mar 18, 2024	D340140
F2426591	Certificate of Analysis	Mar 18, 2024	D340140
F2426592	Certificate of Analysis	Mar 18, 2024	D340140
F2426593	Certificate of Analysis	Mar 18, 2024	D340140

Solubility

Soluble in: DMSO (2.5 mg/mL, warm); ethanol (5 mg/mL, warm); DMF (5 mg/mL)

Boil Point(°C)

~474.5° C at 760 mmHg (Predicted)

Melt Point(°C)

189.27° C (Predicted)

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Basic Description