1,4-DPCA - 98%, high purity , CAS No.331830-20-7

Item Number

D340140

Grouped product items
SKU	Size	Availability	Price
D340140-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$19.90
D340140-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$43.90
D340140-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$72.90
D340140-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$149.90
D340140-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$239.90
D340140-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
D340140-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$879.90

a selective and potent inhibitor of P4HA (α-prolyl 4-hydroxylase)

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Basic Description

Synonyms	EC-000.2078 \| SCHEMBL13225925 \| 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid \| 3-Acetyl-1H-[1,10]phenanthrolin-4-one \| J-019071 \| HMS3649E16 \| SR-01000946603-1 \| PD127748 \| inverted exclamation mark-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	1,4 DPCA is a selective and potent inhibitor of prolyl 4-hydroxylation (P4H)\|in vitro\|. It has been shown to Inhibit α-prolyl 4-hydroxylase, an oxygen-sensing enzyme that targets the pro-angiogenic factor HIF-1α for destruction upon hydroxylation of a specific proline residue. 1,4-DPCA has also been shown to inhibit asparaginyl-hydroxylase factor inhibiting HIF (FIH) and to be useful for controlling excess collagen deposition in pathological fibrosis.

Names and Identifiers

IUPAC Name	4-oxo-1H-1,10-phenanthroline-3-carboxylic acid
INCHI	InChI=1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18)
InChi Key	XZZHOJONZJQARN-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C3=C(C=C2)C(=O)C(=CN3)C(=O)O)N=C1
Isomeric SMILES	C1=CC2=C(C3=C(C=C2)C(=O)C(=CN3)C(=O)O)N=C1
PubChem CID	459803
Molecular Weight	240.21

Certificates

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13 results found

Lot Number	Chart	Certificate Type	Date	Item
F2426570	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426582	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426583	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426584	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426585	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426586	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426587	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426588	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426589	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426590	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426591	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426592	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140
F2426593	¹H MBR	Certificate of Analysis	Mar 18, 2024	D340140

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Solubility

Soluble in: DMSO (2.5 mg/mL, warm); ethanol (5 mg/mL, warm); DMF (5 mg/mL)

Boil Point(°C)

~474.5° C at 760 mmHg (Predicted)

Melt Point(°C)

189.27° C (Predicted)

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