1,5-Diaminonaphthalene - ≥97.0%(HPLC), high purity , CAS No.2243-62-1

11 Citations
  • ≥97%(HPLC)
Item Number
D135799
Grouped product items
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D135799-5g
5g
In stock
$24.90
D135799-25g
25g
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$43.90
D135799-100g
100g
In stock
$123.90
D135799-500g
500g
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$407.90

Basic Description

Synonyms1,5-Diaminonaphthalene | 1,5-NAPHTHALENEDIAMINE | 2243-62-1 | naphthalene-1,5-diamine | 1,5-Naphthylenediamine | NCI-C03021 | 1,5-diamino naphthalene | 13PD3J52LK | DTXSID3020916 | CHEBI:53003 | NSC-401110 | NCGC00091284-03 | 1,5-Diaminonaphthalene (purified by sublimation) | 1,5-
Specifications & Purity≥97%(HPLC)
Shipped InNormal

Associated Targets(Human)

CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR1 Tclin Estrogen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C1 Tclin Glucocorticoid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RUNX1 Tbio Runt-related transcription factor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RORC Tchem Nuclear receptor ROR-gamma (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GALC Tbio Galactocerebrosidase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TNF Tclin Tumor necrosis factor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TSHR Tclin Thyrotropin receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX15B Tchem Arachidonate 15-lipoxygenase B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AHR Tclin Aryl hydrocarbon receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IMPA1 Tclin Inositol monophosphatase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GLS Tchem Glutaminase kidney isoform, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPARD Tchem Peroxisome proliferator-activated receptor delta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CXCL8 Tchem Interleukin-8 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNF Tclin TNF-alpha (1897 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Galc Galactocerebrosidase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488182287
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182287
IUPAC Name naphthalene-1,5-diamine
INCHI InChI=1S/C10H10N2/c11-9-5-1-3-7-8(9)4-2-6-10(7)12/h1-6H,11-12H2
InChi Key KQSABULTKYLFEV-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C=CC=C2N)C(=C1)N
Isomeric SMILES C1=CC2=C(C=CC=C2N)C(=C1)N
WGK Germany 2
RTECS QJ3400000
PubChem CID 16720
UN Number 3077
Packing Group III
Molecular Weight 158.2
Beilstein 13203
Reaxy-Rn 907947

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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13 results found

Lot NumberCertificate TypeDateItem
C2111177Certificate of AnalysisDec 15, 2022 D135799
C2111178Certificate of AnalysisDec 15, 2022 D135799
C2111180Certificate of AnalysisDec 15, 2022 D135799
C1907146Certificate of AnalysisNov 16, 2022 D135799
A2422214Certificate of AnalysisDec 20, 2021 D135799
B2212060Certificate of AnalysisDec 20, 2021 D135799
B2212066Certificate of AnalysisDec 20, 2021 D135799
B2212067Certificate of AnalysisDec 20, 2021 D135799
B2212068Certificate of AnalysisDec 20, 2021 D135799
D2412036Certificate of AnalysisDec 20, 2021 D135799
F2325389Certificate of AnalysisDec 20, 2021 D135799
F2325401Certificate of AnalysisDec 20, 2021 D135799
F2325404Certificate of AnalysisDec 20, 2021 D135799

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Chemical and Physical Properties

SensitivityAir Sensitive
Boil Point(°C)210 °C/5 mmHg
Melt Point(°C)191 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09
Signal Warning
Hazard Statements

H351:Suspected of causing cancer

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P391:Collect spillage.

P203:Obtain, read and follow all safety instructions before use.

P318:if exposed or concerned, get medical advice.

WGK Germany 2
RTECS QJ3400000
Reaxy-Rn 907947
Class 9

Related Documents

Citations of This Product

1. Ning Xu, Guanzheng Cui, Shengyin Zhao, Yu Li, Qian Liu, Xuchang Liu, Chuanliang Zhao, Rongjie Feng, Mingjie Kuang, Shijie Han.  (2023)  Therapeutic Effects of Mechanical Stress-Induced C2C12-Derived Exosomes on Glucocorticoid-Induced Osteoporosis Through miR-92a-3p/PTEN/AKT Signaling Pathway.  International Journal of Nanomedicine,      [PMID:38106447]
2. Panpan Chen, Zihan Zhu, Haoyuan Geng, Xiaoqing Cui, Yuhao Han, Lei Wang, Yaqi Zhang, Heng Lu, Xiao Wang, Yun Zhang, Chenglong Sun.  (2023)  Integrated Spatial Metabolomics and Transcriptomics Decipher the Hepatoprotection Mechanisms of Wedelolactone and Demethylwedelolactone on Non-alcoholic Fatty Liver Disease.  Journal of Pharmaceutical Analysis,    (30):   [PMID:38655398]
3. Yuhao Han, Xinyan Qu, Haoyuan Geng, Lei Wang, Zihan Zhu, Yaqi Zhang, Xiaoqing Cui, Heng Lu, Xiao Wang, Panpan Chen, Quanbo Wang, Chenglong Sun.  (2023)  Isotope-Coded On-Tissue Derivatization for Quantitative Mass Spectrometry Imaging of Short-Chain Fatty Acids in Biological Tissues.  ANALYTICAL CHEMISTRY,      [PMID:37997359]
4. Ma Bangzhen, Zhang Yang, Ma Jiwei, Chen Xinguo, Sun Chenglong, Qin Chengkun.  (2023)  Spatially resolved visualization of reprogrammed metabolism in hepatocellular carcinoma by mass spectrometry imaging.  Cancer Cell International,  23  (1): (1-10).  [PMID:37620880]
5. Lei Wang, Yuhao Han, Yaqi Zhang, Haoyuan Geng, Zihan Zhu, Panpan Chen, Xiaoqing Cui, Xiao Wang, Chenglong Sun.  (2023)  In-depth profiling of carbohydrate isomers in biological tissues by chemical derivatization-assisted mass spectrometry imaging.  ANALYTICA CHIMICA ACTA,  1278  (341741).  [PMID:37709472]
6. Xing Chenyu, Chen Gaoyu, Zhu Xia, An Jiakun, Bao Jianchun, Wang Xuan, Zhou Xiuqing, Du Xiuli, Xu Xiangxing.  (2023)  Synthesis of carbon dots with predictable photoluminescence by the aid of machine learning.  Nano Research,    (1-6).  [PMID:]
7. Chi Zhang, Man Fang, Yuanbo Gao, Yunchao Li, Louzhen Fan, Xiaohong Li.  (2023)  Valence-Engineered Oxidase-Mimicking Nanozyme with Specificity for Aromatic Amine Oxidation and Identification.  ANALYTICAL CHEMISTRY,  95  (28): (10713–10720).  [PMID:37402320]
8. Mengyi Wu, Jiurong Li, Yongzhong Wu, Xiao Gong, Min Wu.  (2023)  Design of a Synthetic Strategy to Achieve Enhanced Fluorescent Carbon Dots with Sulfur and Nitrogen Codoping and Its Multifunctional Applications.  Small,  19  (42): (2302764).  [PMID:37330653]
9. Tongtong Zhu, Lei Cao, Xinyue Kou, Yulu Liu, Wen-Fei Dong, Mingfeng Ge, Li Li.  (2022)  Nitrogen-doped cyan-emissive carbon quantum dots for fluorescence tetracycline detection and lysosome imaging.  RSC Advances,  12  (52): (33761-33771).  [PMID:36505714]
10. Tianyu Ma, Chenglong Sun, Yuhao Han, Lanping Guo, Luqi Huang, Xiao Wang.  (2022)  Matrix-assisted laser desorption/ionization mass spectrometry imaging reveals “Spatial-Temporal-Content” changes of parishins in Gastrodiae Rhizoma during the steaming process.  FOOD RESEARCH INTERNATIONAL,  162  (112092).  [PMID:36461399]
11. Yuhao Han, Yisheng Zhao, Panpan Chen, Lei Wang, Qiongzheng Hu, Xiao Wang, Chenglong Sun.  (2022)  On-tissue derivatization for isomer-specific mass spectrometry imaging and relative quantification of monosaccharides in biological tissues.  ANALYTICA CHIMICA ACTA,  1225  (340241).  [PMID:36038240]

References

1. Ning Xu, Guanzheng Cui, Shengyin Zhao, Yu Li, Qian Liu, Xuchang Liu, Chuanliang Zhao, Rongjie Feng, Mingjie Kuang, Shijie Han.  (2023)  Therapeutic Effects of Mechanical Stress-Induced C2C12-Derived Exosomes on Glucocorticoid-Induced Osteoporosis Through miR-92a-3p/PTEN/AKT Signaling Pathway.  International Journal of Nanomedicine,      [PMID:38106447]
2. Panpan Chen, Zihan Zhu, Haoyuan Geng, Xiaoqing Cui, Yuhao Han, Lei Wang, Yaqi Zhang, Heng Lu, Xiao Wang, Yun Zhang, Chenglong Sun.  (2023)  Integrated Spatial Metabolomics and Transcriptomics Decipher the Hepatoprotection Mechanisms of Wedelolactone and Demethylwedelolactone on Non-alcoholic Fatty Liver Disease.  Journal of Pharmaceutical Analysis,    (30):   [PMID:38655398]
3. Yuhao Han, Xinyan Qu, Haoyuan Geng, Lei Wang, Zihan Zhu, Yaqi Zhang, Xiaoqing Cui, Heng Lu, Xiao Wang, Panpan Chen, Quanbo Wang, Chenglong Sun.  (2023)  Isotope-Coded On-Tissue Derivatization for Quantitative Mass Spectrometry Imaging of Short-Chain Fatty Acids in Biological Tissues.  ANALYTICAL CHEMISTRY,      [PMID:37997359]
4. Ma Bangzhen, Zhang Yang, Ma Jiwei, Chen Xinguo, Sun Chenglong, Qin Chengkun.  (2023)  Spatially resolved visualization of reprogrammed metabolism in hepatocellular carcinoma by mass spectrometry imaging.  Cancer Cell International,  23  (1): (1-10).  [PMID:37620880]
5. Lei Wang, Yuhao Han, Yaqi Zhang, Haoyuan Geng, Zihan Zhu, Panpan Chen, Xiaoqing Cui, Xiao Wang, Chenglong Sun.  (2023)  In-depth profiling of carbohydrate isomers in biological tissues by chemical derivatization-assisted mass spectrometry imaging.  ANALYTICA CHIMICA ACTA,  1278  (341741).  [PMID:37709472]
6. Xing Chenyu, Chen Gaoyu, Zhu Xia, An Jiakun, Bao Jianchun, Wang Xuan, Zhou Xiuqing, Du Xiuli, Xu Xiangxing.  (2023)  Synthesis of carbon dots with predictable photoluminescence by the aid of machine learning.  Nano Research,    (1-6).  [PMID:]
7. Chi Zhang, Man Fang, Yuanbo Gao, Yunchao Li, Louzhen Fan, Xiaohong Li.  (2023)  Valence-Engineered Oxidase-Mimicking Nanozyme with Specificity for Aromatic Amine Oxidation and Identification.  ANALYTICAL CHEMISTRY,  95  (28): (10713–10720).  [PMID:37402320]
8. Mengyi Wu, Jiurong Li, Yongzhong Wu, Xiao Gong, Min Wu.  (2023)  Design of a Synthetic Strategy to Achieve Enhanced Fluorescent Carbon Dots with Sulfur and Nitrogen Codoping and Its Multifunctional Applications.  Small,  19  (42): (2302764).  [PMID:37330653]
9. Tongtong Zhu, Lei Cao, Xinyue Kou, Yulu Liu, Wen-Fei Dong, Mingfeng Ge, Li Li.  (2022)  Nitrogen-doped cyan-emissive carbon quantum dots for fluorescence tetracycline detection and lysosome imaging.  RSC Advances,  12  (52): (33761-33771).  [PMID:36505714]
10. Tianyu Ma, Chenglong Sun, Yuhao Han, Lanping Guo, Luqi Huang, Xiao Wang.  (2022)  Matrix-assisted laser desorption/ionization mass spectrometry imaging reveals “Spatial-Temporal-Content” changes of parishins in Gastrodiae Rhizoma during the steaming process.  FOOD RESEARCH INTERNATIONAL,  162  (112092).  [PMID:36461399]
11. Yuhao Han, Yisheng Zhao, Panpan Chen, Lei Wang, Qiongzheng Hu, Xiao Wang, Chenglong Sun.  (2022)  On-tissue derivatization for isomer-specific mass spectrometry imaging and relative quantification of monosaccharides in biological tissues.  ANALYTICA CHIMICA ACTA,  1225  (340241).  [PMID:36038240]

Solution Calculators