1,6-Dibromo-1,6-dideoxy-D-mannitol - ≥98%, high purity , CAS No.488-41-5

  • ≥98%
Item Number
D355800
Grouped product items
SKUSizeAvailabilityPrice Qty
D355800-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$12.90
D355800-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
D355800-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$149.90

an intermediate for saccharide synthesis

Basic Description

SynonymsDB13543 | D-Mannitol, 1,6-dibromo-1,6-dideoxy- | Myelobromol | EINECS 207-676-8 | MITOBRONITOL [WHO-DD] | NSC-94100 | CS-0007507 | MITOBRONITOL [INN] | MITOBRONITOL [JAN] | NCGC00091099-03 | AKOS024284362 | F76873 | HMS2231P10 | (2S,3S,4S,5S)-1,6-dibromoh
Specifications & Purity≥98%
Biochemical and Physiological MechanismsMitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. Mitobronitol has potential for myelosuppression associated with significantly decreased risk for several compl
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeDISRUPTING AGENT
Product Description

1,6-Dibromo-1,6-dideoxy-D-mannitol is a mannitol derivative with bromides substituted for the terminal hydroxyl groups. 1,6-Dibromo-1,6-dideoxy-D-mannitol is a useful fragment for the synthesis of more complex saccharides and has specifically been described as a starting material for elaboration to 3,4-di-O-acetyl-1,6:2,5-dianhydro-1-thio-D-glucitol as an intermediate in the preparation of glycosyl donors.

Product Properties

ALogP-0.3

Associated Targets(Human)

MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3S,4S,5S)-1,6-dibromohexane-2,3,4,5-tetrol
INCHI InChI=1S/C6H12Br2O4/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,9-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChi Key VFKZTMPDYBFSTM-KVTDHHQDSA-N
Canonical SMILES C(C(C(C(C(CBr)O)O)O)O)Br
Isomeric SMILES C([C@H]([C@H]([C@@H]([C@@H](CBr)O)O)O)O)Br
PubChem CID 656655
Molecular Weight 307.97

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H350:May cause cancer

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

Related Documents

Solution Calculators