1,8-Dihydroxy-3-methylanthraquinone - 97%, high purity , CAS No.481-74-3

  • ≥97%
Item Number
D101144
Grouped product items
SKUSizeAvailabilityPrice Qty
D101144-50mg
50mg
In stock
$48.90
D101144-100mg
100mg
In stock
$78.90
D101144-250mg
250mg
In stock
$177.90
D101144-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$639.90

Basic Description

SynonymsChrysophansaeure | NSC 646567 | BCP23439 | MFCD00001208 | Anthraquinone, 1,8-dihydroxy-3-methyl- | Spectrum_000792 | BRD-K59284035-001-02-0 | C2505 | HSDB 8483 | KBio3_002325 | NCGC00091823-05 | SDCCGMLS-0066504.P001 | 1,8-dihydroxy-3-methyl-9,10-anthraqu
Specifications & Purity≥97%
Storage TempStore at 2-8°C
Shipped InWet ice

Associated Targets(Human)

MGAM Tclin Maltase-glucoamylase (654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY12 Tclin Purinergic receptor P2Y12 (2369 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ELANE Tclin Leukocyte elastase (8173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSG Tchem Cathepsin G (2304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1A1 Tchem Aldehyde reductase (91 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHX2 Tchem Epoxide hydratase (3844 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SI Tchem Sucrase-isomaltase (84 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Calu-1 (518 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Raji (5516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
WISH (126 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A-431 (6446 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H157 (619 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H460 (60772 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A2780 (11979 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HUVEC (11049 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LNCaP (8286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lu1 (576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B10 Tchem Aldo-keto reductase family 1 member B10 (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ME-180 (202 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP2 Tbio Ubiquitin carboxyl-terminal hydrolase 2 (8818 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A6 Tbio UDP-glucuronosyltransferase 1-6 (221 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Alpha-chymotrypsin (819 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ttr Transthyretin (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CELA2A Elastase 2A (403 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus mutans (2687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phytophthora infestans (820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plenodomus lingam (178 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus cereus (7522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium oxysporum (3998 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis B virus (7925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Botrytis cinerea (4183 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
J774.A1 (2436 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INS1 (2867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NIH3T3 (5395 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd2 Thioredoxin reductase 2, mitochondrial (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Erwinia amylovora (182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phytophthora cinnamomi (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhizoctonia solani (2251 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sclerotinia sclerotiorum (877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Spodoptera litura (1708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Estrogen receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Verticillium dahliae (119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sclerotinia minor (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Henosepilachna vigintioctopunctata (143 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium graminearum (1554 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Blumeria hordei (55 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1,8-dihydroxy-3-methylanthracene-9,10-dione
INCHI InChI=1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
InChi Key LQGUBLBATBMXHT-UHFFFAOYSA-N
Canonical SMILES CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
Isomeric SMILES CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
WGK Germany 3
RTECS CB6725000
PubChem CID 10208
Molecular Weight 254.24
Beilstein 1252300
Reaxy-Rn 1252300

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate TypeDateItem
J2418473Certificate of AnalysisOct 26, 2024 D101144
J2418480Certificate of AnalysisOct 26, 2024 D101144
J2418486Certificate of AnalysisOct 26, 2024 D101144
C2405369Certificate of AnalysisMar 15, 2024 D101144
C2405387Certificate of AnalysisMar 15, 2024 D101144
A2203417Certificate of AnalysisOct 12, 2023 D101144
A2203418Certificate of AnalysisOct 12, 2023 D101144
H2322184Certificate of AnalysisAug 29, 2023 D101144
H2322185Certificate of AnalysisAug 29, 2023 D101144
H2322191Certificate of AnalysisAug 29, 2023 D101144
H2322253Certificate of AnalysisAug 29, 2023 D101144
H2322254Certificate of AnalysisAug 29, 2023 D101144
H2322255Certificate of AnalysisAug 29, 2023 D101144

Show more⌵

Chemical and Physical Properties

SolubilityInsoluble in water; Soluble in Benzene,Chloroform,Acetone,Ether; Very slightly soluble in Alcohol
SensitivityAir Sensitive
Melt Point(°C)194-198°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS CB6725000
Reaxy-Rn 1252300
Merck Index 2258

Related Documents

Citations of This Product

1. Senlin Hou, Quancheng Liu, Hu Deng, Jun He, Wei Zhao, Zhixiang Wu, Qi Zhang, Liping Shang.  (2023)  Identification and low-frequency vibrational analysis of three free anthraquinones via terahertz spectroscopy.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  293  (122439).  [PMID:36773425] [10.1016/j.saa.2023.122439]
2. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu.  (2022)  2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae.  RESEARCH IN MICROBIOLOGY,  173  (103955).  [PMID:35550403] [10.1016/j.resmic.2022.103955]
3. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu.  (2022)  Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis.  Frontiers in Pharmacology,  13  (842720).  [PMID:35392552] [10.3389/fphar.2022.842720]
4. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo.  (2022)  Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA.  Foods,  11  (3): (386).  [PMID:35159536] [10.3390/foods11030386]
5. Jin Yang, Yan Cao, Naidong Zhang.  (2020)  Spectrophotometric method for superoxide anion radical detection in a visible light (400–780 nm) system.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  239  (118556).  [PMID:32502811] [10.1016/j.saa.2020.118556]
6. Lizhen Liu, Zhi Mi, Ziying Guo, Junling Wang, Feng Feng.  (2020)  A label-free fluorescent sensor based on carbon quantum dots with enhanced sensitive for the determination of myricetin in real samples.  MICROCHEMICAL JOURNAL,  157  (104956).  [PMID:] [10.1016/j.microc.2020.104956]
7. Chi Chen, Zhuang Fu, Weiying Zhou, Qiushi Chen, Chenzhao Wang, Lu Xu, Zhibing Wang, Hanqi Zhang.  (2020)  Ionic liquid-immobilized NaY zeolite-based matrix solid phase dispersion for the extraction of active constituents in Rheum palmatum L..  MICROCHEMICAL JOURNAL,  152  (104245).  [PMID:] [10.1016/j.microc.2019.104245]
8. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan.  (2017)  Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L..  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (21):   [PMID:] [10.1002/app.44874]
9. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun.  (2015)  Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea.  JOURNAL OF SEPARATION SCIENCE,  38  (8): (1263-1270).  [PMID:25677958] [10.1002/jssc.201401341]
10. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun.  (2014)  Effects of several quinones on insulin aggregation.  Scientific Reports,  (1): (1-8).  [PMID:25008537] [10.1038/srep05648]

References

1. Su-Jin Kim,Min-Cheol Kim,Byong-Joo Lee,Dae-Hee Park,Seung-Heon Hong,Jae-Young Um.  (2010-09-30)  Anti-Inflammatory activity of chrysophanol through the suppression of NF-kappaB/caspase-1 activation in vitro and in vivo..  Molecules (Basel, Switzerland),  15  ((9)): (6436-6451).  [PMID:20877234]
2. Myung Sun Lee,Eun Young Cha,Ji Young Sul,In Sang Song,Ji Yeon Kim.  (2010-11-23)  Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway..  Phytotherapy research : PTR,  25  ((6)): (833-837).  [PMID:21089180]
3. Shuying Guo,Bo Feng,Ruonan Zhu,Jiankang Ma,Wei Wang.  (2011-01-29)  Preparative isolation of three anthraquinones from Rumex japonicus by high-speed counter-current chromatography..  Molecules (Basel, Switzerland),  16  ((2)): (1201-1210).  [PMID:21273951]
4. Chang-Heng Liu,Xue-Kui Xia,Jun Qi,Yong-Gang Zhang,Wen-Peng Yuan,Xiu-Mei Meng,Ai-Rong Jia,Yong-Jun Sun,Wei Hu.  (2011-05-10)  [The secondary metabolites of the HS-3 Alternaria sp. fungus associated with holothurians]..  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,  33  ((12)): (1875-1877).  [PMID:21548363]
5. Lijia Xu,Chi-On Chan,Ching-Ching Lau,Zhiling Yu,Daniel K W Mok,Sibao Chen.  (2011-05-28)  Simultaneous determination of eight anthraquinones in Semen Cassiae by HPLC-DAD..  Phytochemical analysis : PCA,  23  ((2)): (110-116).  [PMID:21618311]
6. Li-Chun Zhao,Jian Liang,Wei Li,Kun-Mu Cheng,Xianghua Xia,Xin Deng,Geng-Liang Yang.  (2011-07-19)  The use of response surface methodology to optimize the ultrasound-assisted extraction of five anthraquinones from Rheum palmatum L..  Molecules (Basel, Switzerland),  16  ((7)): (5928-5937).  [PMID:21765390]
7. Fang Fang,Jia-bo Wang,Yan-ling Zhao,Cheng Jin,Wei-jun Kong,Hai-ping Zhao,Hong-juan Wang,Xiao-he Xiao.  (2011-09-03)  A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract..  Journal of ethnopharmacology,  137  ((3)): (1492-1497).  [PMID:21884773]
8. Ying Shi,Chengjun Sun,Bo Gao,Aimin Sun.  (2011-09-09)  Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods..  Journal of chromatography. A,  1218  ((42)): (7655-7662).  [PMID:21899853]
9. H Ibrahim,B B Mdau,A Ahmed,M Ilyas.  (2012-01-13)  Anthraquinones of Cissus populnea Guill & Perr (Amplidaceae)..  African journal of traditional, complementary, and alternative medicines : AJTCAM,  ((2)): (140-143).  [PMID:22238494]
10. Hui Zhang,Zengjun Guo,Nan Wu,Wenming Xu,Ling Han,Nan Li,Yanxia Han.  (2012-01-19)  Two novel naphthalene glucosides and an anthraquinone isolated from Rumex dentatus and their antiproliferation activities in four cell lines..  Molecules (Basel, Switzerland),  17  ((1)): (843-850).  [PMID:22252500]
11. Zhi-Xiong Zhang,Yong-Feng Liang.  (2012-01-21)  [Study on chemical constituents from the root of Hemerocallis citrina]..  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,  34  ((9)): (1371-1373).  [PMID:22260003]
12. Tiffany Chien-Ting Lo,Hung-Chi Nian,Kong-Hwa Chiu,Ai-Yih Wang,Ben-Zen Wu.  (2012-03-23)  Rapid and efficient purification of chrysophanol in Rheum Palmatum LINN by supercritical fluid extraction coupled with preparative liquid chromatography in tandem..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  893-894  (101-106).  [PMID:22436825]
13. Yuying Wang,Weihong Feng,Fei Yang,Qiwei Zhang,Lina Ji,Dongying Li,Zhimin Wang.  (2012-06-29)  [Determination of four anthraquinones in Sanhuang tablets by QAMS]..  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,  37  ((2)): (212-217).  [PMID:22737853]
14. Han-Lin Gong,Wen-Fu Tang,Jia Wang,Guang-Yuan Chen,Xi Huang.  (2012-09-01)  Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats..  Chinese journal of integrative medicine,  18  ((9)): (708-713).  [PMID:22936325]
15. Haiming Chen,Yucui Li,Xiaoli Wu,Chuwen Li,Qingguo Li,Zhen Qin,Yuyang Yi,Jiannan Chen,Xiaoping Lai,Ziren Su.  (2013-03-19)  LC-MS/MS determination of pogostone in rat plasma and its application in pharmacokinetic studies..  Biomedical chromatography : BMC,  27  ((9)): (1092-1099).  [PMID:23505096]
16. Wasim Ahmad,Syed Mohammad Arif Zaidi,Mohd Mujeeb,Shahid Hussain Ansari,Sayeed Ahmad.  (2013-08-28)  HPLC and HPTLC methods by design for quantitative characterization and in vitro anti-oxidant activity of polyherbal formulation containing Rheum emodi..  Journal of chromatographic science,  52  ((8)): (911-918).  [PMID:23978770]
17. Shu-Jen Chang,Su-Hua Huang,Ying-Ju Lin,Yi-Yun Tsou,Cheng-Wen Lin.  (2014-01-08)  Antiviral activity of Rheum palmatum methanol extract and chrysophanol against Japanese encephalitis virus..  Archives of pharmacal research,  37  ((9)): (1117-1123).  [PMID:24395532]
18. Xiao-Hong Gong,Yan Li,Ruo-Qi Zhang,Xiao-Fang Xie,Cheng Peng,Yun-Xia Li.  (2014-07-06)  The synergism mechanism of Rhubarb Anthraquinones on constipation elucidated by comparative pharmacokinetics of Rhubarb extract between normal and diseased rats..  European journal of drug metabolism and pharmacokinetics,  40  ((4)): (379-388).  [PMID:24996641]
19. Xiao Liu,Huan Li,Li Wu,Jiangwa Xing,Yanhong Poh,Hao Cai,Bao Chang Cai.  (2015-01-20)  Simultaneous quantification of chrysophanol and physcion in rat plasma by ultra fast liquid chromatography-tandem mass spectrometry and application of the technique to comparative pharmacokinetic studies of Radix et Rhei Rhizoma extract alone and Dahuang Fuzi Decoction..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  980  (88-93).  [PMID:25597888]
20. Gati Krushna Panigrahi,Ratnasekhar Ch,Mohana K R Mudiam,Vipin M Vashishtha,S Raisuddin,Mukul Das.  (2015-04-29)  Activity-guided chemo toxic profiling of Cassia occidentalis (CO) seeds: detection of toxic compounds in body fluids of CO-exposed patients and experimental rats..  Chemical research in toxicology,  28  ((6)): (1120-1132).  [PMID:25915165]
21. Kyoung Jin Nho,Jin Mi Chun,A Young Lee,Ho Kyoung Kim.  (2015-06-10)  Anti-metastatic effects of Rheum Palmatum L. extract in human MDA-MB-231 breast cancer cells..  Environmental toxicology and pharmacology,  40  ((1)): (30-38).  [PMID:26056975]
22. Haoxie Xu,Yuqin Lu,Tingting Zhang,Ke Liu,Lizhong Liu,Zhendan He,Bingqi Xu,Xuli Wu.  (2019-01-20)  Characterization of binding interactions of anthraquinones and bovine β-lactoglobulin..  Food chemistry,  281  (28-35).  [PMID:30658758]
23. Xiaoping Huang,Guoyue Zhong,Xuemei Zhang,Yi Zhang.  (2010-11-05)  [Determination of aurantio-obtusin and chrysophanol in cassiae semen by HPLC]..  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,  35  ((16)): (2065-2067).  [PMID:21046729]
24. Xue-ru Zhang,Jia-bo Wang,Xiao-he Xiao,Ta-si Liu,Xiao-hui Chu,Can-ping Zhou,Cheng Jin.  (2011-03-01)  [Antimicrobial activity and chemical differences between the two chemotypes of rhubarbs]..  Yao xue xue bao = Acta pharmaceutica Sinica,  45  ((9)): (1144-1148).  [PMID:21351571]
25. Yanhong Wang,Xiaomin Wu,Xindong Yang,Xiaokun Li.  (2011-06-30)  [Studies on identification and secondary metabolites of endophytic fungi strain E8 from Curcuma wenyujin]..  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,  36  ((6)): (770-774).  [PMID:21710748]
26. Xian Ding,Bo Yin,Li Qian,Zhirui Zeng,Zeliang Yang,Huixian Li,Yongjun Lu,Shining Zhou.  (2011-08-20)  Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm..  Journal of medical microbiology,  60  ((Pt 12)): (1827-1834).  [PMID:21852522]
27. Chu VanMen,Yu Seon Jang,Hong Mei Zhu,Jae Hyun Lee,Trinh Nam Trung,Tran Minh Ngoc,Young Ho Kim,Jong Seong Kang.  (2011-10-20)  Chemical-based species classification of rhubarb using simultaneous determination of five bioactive substances by HPLC and LDA analysis..  Phytochemical analysis : PCA,  23  ((4)): (359-364).  [PMID:22009582]
28. De-lin Wu,Shi-yun Chen,Jing-song Liu,Chuan-shan Jin,Feng-qing Xu.  (2011-11-10)  [Chemical constituents of Carya cathayensis and their antitumor bioactivity]..  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,  34  ((7)): (1055-1057).  [PMID:22066397]
29. Chien-Hang Ni,Po-Yuan Chen,Hsu-Feng Lu,Jai-Sing Yang,Hui-Ying Huang,Shin-Hwar Wu,Siu-Wan Ip,Chin-Tung Wu,Su-Yin Chiang,Jaung-Geng Lin,W Gibson Wood,Jing-Gung Chung.  (2012-05-31)  Chrysophanol-induced necrotic-like cell death through an impaired mitochondrial ATP synthesis in Hep3B human liver cancer cells..  Archives of pharmacal research,  35  ((5)): (887-895).  [PMID:22644856]
30. Jackson Roberto Guedes da Silva Almeida,Edigênia Cavalcante da Cruz Araújo,Luciano Augusto de Araújo Ribeiro,Julianeli Tolentino de Lima,Xirley Pereira Nunes,Ana Sílvia Suassuna Carneiro Lúcio,Maria de Fátima Agra,José Maria Barbosa Filho.  (2012-05-31)  Antinociceptive activity of ethanol extract from Duguetia chrysocarpa Maas (Annonaceae)..  TheScientificWorldJournal,  2012  (859210-859210).  [PMID:22645460]
31. Anne C Jones,Donald E Mullins,Tappey H Jones,Scott M Salom.  (2012-06-23)  Potential feeding deterrents found in hemlock woolly adelgid, Adelges tsugae..  Die Naturwissenschaften,  99  ((7)): (583-586).  [PMID:22722375]
32. Zhi-sen Wang,Gui-ru Han,Fei Gao,Li-na An,Yu-zhe Ji.  (2012-12-12)  [New method of processing on Rhei Radix Et Rhizoma and study on quality control of its processing products]..  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,  35  ((5)): (699-702).  [PMID:23213729]
33. Li Chu,Huaxin Zhao,Juemin Fang,Chunyan Li,Zhuqing Liu,Ran Cui,Fei Hu,Xi Zhang,Yijing Chen,Hui Han,Chuanhai Cao,Qing Xu.  (2015-01-22)  The traditional Chinese medicinal formula BDL301 suppresses tumor growth by inhibiting STAT3 pathway and inducing apoptosis in colorectal cancer cells..  DNA and cell biology,  34  ((3)): (178-188).  [PMID:25607688]
34. Fuqing Lin,Chen Zhang,Xianzhen Chen,E Song,Shiyu Sun,Minghui Chen,Tao Pan,Xiaoming Deng.  (2015-06-13)  Chrysophanol affords neuroprotection against microglial activation and free radical-mediated oxidative damage in BV2 murine microglia..  International journal of clinical and experimental medicine,  ((3)): (3447-3455).  [PMID:26064235]
35. Hee-Yun Kim,Hyunwoo Jee,Jun-Ho Yeom,Hyun-Ja Jeong,Hyung-Min Kim.  (2019-03-16)  The ameliorative effect of AST2017-01 in an ovalbumin-induced allergic rhinitis animal model..  Inflammation research : official journal of the European Histamine Research Society ... [et al.],  68  ((5)): (387-395).  [PMID:30874868]
36. Senlin Hou, Quancheng Liu, Hu Deng, Jun He, Wei Zhao, Zhixiang Wu, Qi Zhang, Liping Shang.  (2023)  Identification and low-frequency vibrational analysis of three free anthraquinones via terahertz spectroscopy.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  293  (122439).  [PMID:36773425] [10.1016/j.saa.2023.122439]
37. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu.  (2022)  2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae.  RESEARCH IN MICROBIOLOGY,  173  (103955).  [PMID:35550403] [10.1016/j.resmic.2022.103955]
38. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu.  (2022)  Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis.  Frontiers in Pharmacology,  13  (842720).  [PMID:35392552] [10.3389/fphar.2022.842720]
39. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo.  (2022)  Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA.  Foods,  11  (3): (386).  [PMID:35159536] [10.3390/foods11030386]
40. Jin Yang, Yan Cao, Naidong Zhang.  (2020)  Spectrophotometric method for superoxide anion radical detection in a visible light (400–780 nm) system.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  239  (118556).  [PMID:32502811] [10.1016/j.saa.2020.118556]
41. Lizhen Liu, Zhi Mi, Ziying Guo, Junling Wang, Feng Feng.  (2020)  A label-free fluorescent sensor based on carbon quantum dots with enhanced sensitive for the determination of myricetin in real samples.  MICROCHEMICAL JOURNAL,  157  (104956).  [PMID:] [10.1016/j.microc.2020.104956]
42. Chi Chen, Zhuang Fu, Weiying Zhou, Qiushi Chen, Chenzhao Wang, Lu Xu, Zhibing Wang, Hanqi Zhang.  (2020)  Ionic liquid-immobilized NaY zeolite-based matrix solid phase dispersion for the extraction of active constituents in Rheum palmatum L..  MICROCHEMICAL JOURNAL,  152  (104245).  [PMID:] [10.1016/j.microc.2019.104245]
43. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan.  (2017)  Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L..  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (21):   [PMID:] [10.1002/app.44874]
44. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun.  (2015)  Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea.  JOURNAL OF SEPARATION SCIENCE,  38  (8): (1263-1270).  [PMID:25677958] [10.1002/jssc.201401341]
45. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun.  (2014)  Effects of several quinones on insulin aggregation.  Scientific Reports,  (1): (1-8).  [PMID:25008537] [10.1038/srep05648]

Solution Calculators