Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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D101144-50mg | 50mg | In stock | $48.90 | |
D101144-100mg | 100mg | In stock | $78.90 | |
D101144-250mg | 250mg | In stock | $177.90 | |
D101144-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $639.90 |
Synonyms | Chrysophansaeure | NSC 646567 | BCP23439 | MFCD00001208 | Anthraquinone, 1,8-dihydroxy-3-methyl- | Spectrum_000792 | BRD-K59284035-001-02-0 | C2505 | HSDB 8483 | KBio3_002325 | NCGC00091823-05 | SDCCGMLS-0066504.P001 | 1,8-dihydroxy-3-methyl-9,10-anthraqu |
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Specifications & Purity | ≥97% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1,8-dihydroxy-3-methylanthracene-9,10-dione |
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INCHI | InChI=1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3 |
InChi Key | LQGUBLBATBMXHT-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O |
Isomeric SMILES | CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O |
WGK Germany | 3 |
RTECS | CB6725000 |
PubChem CID | 10208 |
Molecular Weight | 254.24 |
Beilstein | 1252300 |
Reaxy-Rn | 1252300 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
J2418473 | Certificate of Analysis | Oct 26, 2024 | D101144 |
J2418480 | Certificate of Analysis | Oct 26, 2024 | D101144 |
J2418486 | Certificate of Analysis | Oct 26, 2024 | D101144 |
C2405369 | Certificate of Analysis | Mar 15, 2024 | D101144 |
C2405387 | Certificate of Analysis | Mar 15, 2024 | D101144 |
A2203417 | Certificate of Analysis | Oct 12, 2023 | D101144 |
A2203418 | Certificate of Analysis | Oct 12, 2023 | D101144 |
H2322184 | Certificate of Analysis | Aug 29, 2023 | D101144 |
H2322185 | Certificate of Analysis | Aug 29, 2023 | D101144 |
H2322191 | Certificate of Analysis | Aug 29, 2023 | D101144 |
H2322253 | Certificate of Analysis | Aug 29, 2023 | D101144 |
H2322254 | Certificate of Analysis | Aug 29, 2023 | D101144 |
H2322255 | Certificate of Analysis | Aug 29, 2023 | D101144 |
Solubility | Insoluble in water; Soluble in Benzene,Chloroform,Acetone,Ether; Very slightly soluble in Alcohol |
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Sensitivity | Air Sensitive |
Melt Point(°C) | 194-198°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | CB6725000 |
Reaxy-Rn | 1252300 |
Merck Index | 2258 |
1. Senlin Hou, Quancheng Liu, Hu Deng, Jun He, Wei Zhao, Zhixiang Wu, Qi Zhang, Liping Shang. (2023) Identification and low-frequency vibrational analysis of three free anthraquinones via terahertz spectroscopy. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 293 (122439). [PMID:36773425] [10.1016/j.saa.2023.122439] |
2. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu. (2022) 2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae. RESEARCH IN MICROBIOLOGY, 173 (103955). [PMID:35550403] [10.1016/j.resmic.2022.103955] |
3. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu. (2022) Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis. Frontiers in Pharmacology, 13 (842720). [PMID:35392552] [10.3389/fphar.2022.842720] |
4. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo. (2022) Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA. Foods, 11 (3): (386). [PMID:35159536] [10.3390/foods11030386] |
5. Jin Yang, Yan Cao, Naidong Zhang. (2020) Spectrophotometric method for superoxide anion radical detection in a visible light (400–780 nm) system. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118556). [PMID:32502811] [10.1016/j.saa.2020.118556] |
6. Lizhen Liu, Zhi Mi, Ziying Guo, Junling Wang, Feng Feng. (2020) A label-free fluorescent sensor based on carbon quantum dots with enhanced sensitive for the determination of myricetin in real samples. MICROCHEMICAL JOURNAL, 157 (104956). [PMID:] [10.1016/j.microc.2020.104956] |
7. Chi Chen, Zhuang Fu, Weiying Zhou, Qiushi Chen, Chenzhao Wang, Lu Xu, Zhibing Wang, Hanqi Zhang. (2020) Ionic liquid-immobilized NaY zeolite-based matrix solid phase dispersion for the extraction of active constituents in Rheum palmatum L.. MICROCHEMICAL JOURNAL, 152 (104245). [PMID:] [10.1016/j.microc.2019.104245] |
8. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan. (2017) Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L.. JOURNAL OF APPLIED POLYMER SCIENCE, 134 (21): [PMID:] [10.1002/app.44874] |
9. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun. (2015) Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea. JOURNAL OF SEPARATION SCIENCE, 38 (8): (1263-1270). [PMID:25677958] [10.1002/jssc.201401341] |
10. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun. (2014) Effects of several quinones on insulin aggregation. Scientific Reports, 4 (1): (1-8). [PMID:25008537] [10.1038/srep05648] |
1. Su-Jin Kim,Min-Cheol Kim,Byong-Joo Lee,Dae-Hee Park,Seung-Heon Hong,Jae-Young Um. (2010-09-30) Anti-Inflammatory activity of chrysophanol through the suppression of NF-kappaB/caspase-1 activation in vitro and in vivo.. Molecules (Basel, Switzerland), 15 ((9)): (6436-6451). [PMID:20877234] |
2. Myung Sun Lee,Eun Young Cha,Ji Young Sul,In Sang Song,Ji Yeon Kim. (2010-11-23) Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway.. Phytotherapy research : PTR, 25 ((6)): (833-837). [PMID:21089180] |
3. Shuying Guo,Bo Feng,Ruonan Zhu,Jiankang Ma,Wei Wang. (2011-01-29) Preparative isolation of three anthraquinones from Rumex japonicus by high-speed counter-current chromatography.. Molecules (Basel, Switzerland), 16 ((2)): (1201-1210). [PMID:21273951] |
4. Chang-Heng Liu,Xue-Kui Xia,Jun Qi,Yong-Gang Zhang,Wen-Peng Yuan,Xiu-Mei Meng,Ai-Rong Jia,Yong-Jun Sun,Wei Hu. (2011-05-10) [The secondary metabolites of the HS-3 Alternaria sp. fungus associated with holothurians].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 33 ((12)): (1875-1877). [PMID:21548363] |
5. Lijia Xu,Chi-On Chan,Ching-Ching Lau,Zhiling Yu,Daniel K W Mok,Sibao Chen. (2011-05-28) Simultaneous determination of eight anthraquinones in Semen Cassiae by HPLC-DAD.. Phytochemical analysis : PCA, 23 ((2)): (110-116). [PMID:21618311] |
6. Li-Chun Zhao,Jian Liang,Wei Li,Kun-Mu Cheng,Xianghua Xia,Xin Deng,Geng-Liang Yang. (2011-07-19) The use of response surface methodology to optimize the ultrasound-assisted extraction of five anthraquinones from Rheum palmatum L.. Molecules (Basel, Switzerland), 16 ((7)): (5928-5937). [PMID:21765390] |
7. Fang Fang,Jia-bo Wang,Yan-ling Zhao,Cheng Jin,Wei-jun Kong,Hai-ping Zhao,Hong-juan Wang,Xiao-he Xiao. (2011-09-03) A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract.. Journal of ethnopharmacology, 137 ((3)): (1492-1497). [PMID:21884773] |
8. Ying Shi,Chengjun Sun,Bo Gao,Aimin Sun. (2011-09-09) Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods.. Journal of chromatography. A, 1218 ((42)): (7655-7662). [PMID:21899853] |
9. H Ibrahim,B B Mdau,A Ahmed,M Ilyas. (2012-01-13) Anthraquinones of Cissus populnea Guill & Perr (Amplidaceae).. African journal of traditional, complementary, and alternative medicines : AJTCAM, 8 ((2)): (140-143). [PMID:22238494] |
10. Hui Zhang,Zengjun Guo,Nan Wu,Wenming Xu,Ling Han,Nan Li,Yanxia Han. (2012-01-19) Two novel naphthalene glucosides and an anthraquinone isolated from Rumex dentatus and their antiproliferation activities in four cell lines.. Molecules (Basel, Switzerland), 17 ((1)): (843-850). [PMID:22252500] |
11. Zhi-Xiong Zhang,Yong-Feng Liang. (2012-01-21) [Study on chemical constituents from the root of Hemerocallis citrina].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34 ((9)): (1371-1373). [PMID:22260003] |
12. Tiffany Chien-Ting Lo,Hung-Chi Nian,Kong-Hwa Chiu,Ai-Yih Wang,Ben-Zen Wu. (2012-03-23) Rapid and efficient purification of chrysophanol in Rheum Palmatum LINN by supercritical fluid extraction coupled with preparative liquid chromatography in tandem.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 893-894 (101-106). [PMID:22436825] |
13. Yuying Wang,Weihong Feng,Fei Yang,Qiwei Zhang,Lina Ji,Dongying Li,Zhimin Wang. (2012-06-29) [Determination of four anthraquinones in Sanhuang tablets by QAMS].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37 ((2)): (212-217). [PMID:22737853] |
14. Han-Lin Gong,Wen-Fu Tang,Jia Wang,Guang-Yuan Chen,Xi Huang. (2012-09-01) Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats.. Chinese journal of integrative medicine, 18 ((9)): (708-713). [PMID:22936325] |
15. Haiming Chen,Yucui Li,Xiaoli Wu,Chuwen Li,Qingguo Li,Zhen Qin,Yuyang Yi,Jiannan Chen,Xiaoping Lai,Ziren Su. (2013-03-19) LC-MS/MS determination of pogostone in rat plasma and its application in pharmacokinetic studies.. Biomedical chromatography : BMC, 27 ((9)): (1092-1099). [PMID:23505096] |
16. Wasim Ahmad,Syed Mohammad Arif Zaidi,Mohd Mujeeb,Shahid Hussain Ansari,Sayeed Ahmad. (2013-08-28) HPLC and HPTLC methods by design for quantitative characterization and in vitro anti-oxidant activity of polyherbal formulation containing Rheum emodi.. Journal of chromatographic science, 52 ((8)): (911-918). [PMID:23978770] |
17. Shu-Jen Chang,Su-Hua Huang,Ying-Ju Lin,Yi-Yun Tsou,Cheng-Wen Lin. (2014-01-08) Antiviral activity of Rheum palmatum methanol extract and chrysophanol against Japanese encephalitis virus.. Archives of pharmacal research, 37 ((9)): (1117-1123). [PMID:24395532] |
18. Xiao-Hong Gong,Yan Li,Ruo-Qi Zhang,Xiao-Fang Xie,Cheng Peng,Yun-Xia Li. (2014-07-06) The synergism mechanism of Rhubarb Anthraquinones on constipation elucidated by comparative pharmacokinetics of Rhubarb extract between normal and diseased rats.. European journal of drug metabolism and pharmacokinetics, 40 ((4)): (379-388). [PMID:24996641] |
19. Xiao Liu,Huan Li,Li Wu,Jiangwa Xing,Yanhong Poh,Hao Cai,Bao Chang Cai. (2015-01-20) Simultaneous quantification of chrysophanol and physcion in rat plasma by ultra fast liquid chromatography-tandem mass spectrometry and application of the technique to comparative pharmacokinetic studies of Radix et Rhei Rhizoma extract alone and Dahuang Fuzi Decoction.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980 (88-93). [PMID:25597888] |
20. Gati Krushna Panigrahi,Ratnasekhar Ch,Mohana K R Mudiam,Vipin M Vashishtha,S Raisuddin,Mukul Das. (2015-04-29) Activity-guided chemo toxic profiling of Cassia occidentalis (CO) seeds: detection of toxic compounds in body fluids of CO-exposed patients and experimental rats.. Chemical research in toxicology, 28 ((6)): (1120-1132). [PMID:25915165] |
21. Kyoung Jin Nho,Jin Mi Chun,A Young Lee,Ho Kyoung Kim. (2015-06-10) Anti-metastatic effects of Rheum Palmatum L. extract in human MDA-MB-231 breast cancer cells.. Environmental toxicology and pharmacology, 40 ((1)): (30-38). [PMID:26056975] |
22. Haoxie Xu,Yuqin Lu,Tingting Zhang,Ke Liu,Lizhong Liu,Zhendan He,Bingqi Xu,Xuli Wu. (2019-01-20) Characterization of binding interactions of anthraquinones and bovine β-lactoglobulin.. Food chemistry, 281 (28-35). [PMID:30658758] |
23. Xiaoping Huang,Guoyue Zhong,Xuemei Zhang,Yi Zhang. (2010-11-05) [Determination of aurantio-obtusin and chrysophanol in cassiae semen by HPLC].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 35 ((16)): (2065-2067). [PMID:21046729] |
24. Xue-ru Zhang,Jia-bo Wang,Xiao-he Xiao,Ta-si Liu,Xiao-hui Chu,Can-ping Zhou,Cheng Jin. (2011-03-01) [Antimicrobial activity and chemical differences between the two chemotypes of rhubarbs].. Yao xue xue bao = Acta pharmaceutica Sinica, 45 ((9)): (1144-1148). [PMID:21351571] |
25. Yanhong Wang,Xiaomin Wu,Xindong Yang,Xiaokun Li. (2011-06-30) [Studies on identification and secondary metabolites of endophytic fungi strain E8 from Curcuma wenyujin].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36 ((6)): (770-774). [PMID:21710748] |
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