Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | danthron | 1,8-Dihydroxyanthraquinone | 117-10-2 | Chrysazin | Dantron | Antrapurol | Dorbane | Istizin | Laxanthreen | Diaquone | Laxanorm | Altan | 1,8-Dihydroxyanthracene-9,10-dione | Laxipurin | Zwitsalax | Danivac | Dionone | Duolax | Laxipur | 9,10-Anthracenedione, 1,8-dihydroxy- | danthr |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
Product Properties
| ALogP | 3.2 |
|---|
Associated Targets(Human)
ESR1 Tclin Estrogen receptor (0 Activities)
EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CSNK2A1 Tchem Casein kinase II subunit alpha (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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RORC Tchem Nuclear receptor ROR-gamma (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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VDR Tclin Vitamin D3 receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HDAC6 Tclin Histone deacetylase 6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KAT2A Tchem Histone acetyltransferase KAT2A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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TXNRD2 Tbio Thioredoxin reductase 2, mitochondrial (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SMN1 Tchem Survival motor neuron protein (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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UGT1A9 Tbio UDP-glucuronosyltransferase 1-9 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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TSHR Tclin Thyrotropin receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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TTR Tclin Transthyretin (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PMP22 Tbio Peripheral myelin protein 22 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
LMNA Tbio Prelamin-A/C (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALOX15 Tchem Arachidonate 15-lipoxygenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MBNL1 Tbio Muscleblind-like protein 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MAOB Tclin Amine oxidase [flavin-containing] B (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MAOA Tclin Amine oxidase [flavin-containing] A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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UGT1A6 Tbio UDP-glucuronosyltransferase 1-6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
UGT1A7 Tbio UDP-glucuronosyltransferase 1-7 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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THRB Tclin Thyroid hormone receptor beta (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MAPT Tclin Microtubule-associated protein tau (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HTT Tchem Huntingtin (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PPARD Tchem Peroxisome proliferator-activated receptor delta (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PPARG Tclin Peroxisome proliferator-activated receptor gamma (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NEU2 Tbio Sialidase-2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CXCL8 Tchem Interleukin-8 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MAPK1 Tchem Mitogen-activated protein kinase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MSR1 Tbio Macrophage scavenger receptor types I and II (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ESR1 Tclin Estrogen receptor alpha (17718 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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VDR Tclin Vitamin D receptor (26531 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MAOA Tclin Monoamine oxidase A (11911 Activities)
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MAOB Tclin Monoamine oxidase B (8835 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
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THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CXCL8 Tchem Interleukin-8 (642 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)
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NEU2 Tbio Sialidase 2 (382 Activities)
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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
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ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
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A498 (42825 Activities)
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ACHN (49357 Activities)
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BT-474 (2113 Activities)
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BXPC-3 (2997 Activities)
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CAKI-1 (44928 Activities)
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CCRF-CEM (65223 Activities)
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COLO 205 (50209 Activities)
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DLD-1 (17511 Activities)
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DMS-273 (14108 Activities)
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HT-29 (80576 Activities)
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K562 (73714 Activities)
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KM12 (47707 Activities)
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M14 (47487 Activities)
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MCF-10A (2462 Activities)
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MOLT-4 (49676 Activities)
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OVCAR-3 (48710 Activities)
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OVCAR-4 (44535 Activities)
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OVCAR-5 (45555 Activities)
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OVCAR-8 (47708 Activities)
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PANC-1 (6144 Activities)
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Raji (5516 Activities)
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RPMI-8226 (44974 Activities)
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RXF 393 (41971 Activities)
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SF-295 (48000 Activities)
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SK-MEL-2 (46422 Activities)
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SK-MEL-28 (48833 Activities)
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SK-OV-3 (52876 Activities)
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SN12C (47755 Activities)
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SNB-19 (46794 Activities)
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SNB-78 (14240 Activities)
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TK-10 (45540 Activities)
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U-251 (51189 Activities)
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UACC-257 (46019 Activities)
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UACC-62 (47335 Activities)
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UO-31 (46270 Activities)
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XF498 (12972 Activities)
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786-0 (47912 Activities)
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Associated Targets(non-human)
Ttr Transthyretin (14 Activities)
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Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mapk1 MAP kinase ERK2 (650 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Msr1 Scavenger receptor type A (57 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Pseudomonas aeruginosa (123386 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Proteus vulgaris (5823 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Escherichia coli (133304 Activities)
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Proteus mirabilis (3894 Activities)
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Streptococcus mutans (2687 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Trypanosoma brucei brucei (13300 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Plasmodium falciparum (966862 Activities)
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Candida albicans (78123 Activities)
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Trichoplusia ni (986 Activities)
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GCN5 Histone acetyltransferase GCN5 (89 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Txnrd2 Thioredoxin reductase 2, mitochondrial (18 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mapt Microtubule-associated protein tau (6 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Rorc Nuclear receptor ROR-gamma (89407 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ESR1 Estrogen receptor (4 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SARS-CoV-2 (38078 Activities)
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Names and Identifiers
| IUPAC Name | 1,8-dihydroxyanthracene-9,10-dione |
|---|---|
| INCHI | InChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H |
| InChi Key | QBPFLULOKWLNNW-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O |
| Isomeric SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O |
| WGK Germany | 1 |
| RTECS | CB6650000 |
| PubChem CID | 2950 |
| UN Number | 2811 |
| Packing Group | I |
| Molecular Weight | 240.21 |
| Beilstein | 2054727 |
| Reaxy-Rn | 2054727 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | Light sensitive. |
|---|---|
| Melt Point(°C) | 191-193°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08 |
|---|---|
| Signal | Warning |
| Hazard Statements | H351:Suspected of causing cancer |
| Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
| WGK Germany | 1 |
| RTECS | CB6650000 |
| Reaxy-Rn | 2054727 |
| Class | 6.1 |
| Merck Index | 2815 |
Related Documents
Citations of This Product
| 1. Huibin Guo, Yidan Wang, Kaixing Yao, Han Zheng, Xinji Zhang, Rui Li, Ning Wang, Haiyan Fu. (2023) The overlooked formation of environmentally persistent free radicals on particulate matter collected from biomass burning under light irradiation. ENVIRONMENT INTERNATIONAL, 171 (107668). [PMID:36459822] |
| 2. Chun-Yang Li, Shi-Wen Lv, Lu Yang, Jin Wang, Jing-Min Liu, Shuo Wang. (2022) Facile preparation of uniform-sized covalent organic framework nanoflowers as versatile sample-pretreatment platforms for sensitive and specific determination of hazardous substances. JOURNAL OF HAZARDOUS MATERIALS, 438 (129566). [PMID:35999751] |
| 3. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu. (2022) 2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae. RESEARCH IN MICROBIOLOGY, 173 (103955). [PMID:35550403] |
References
| 1. Huibin Guo, Yidan Wang, Kaixing Yao, Han Zheng, Xinji Zhang, Rui Li, Ning Wang, Haiyan Fu. (2023) The overlooked formation of environmentally persistent free radicals on particulate matter collected from biomass burning under light irradiation. ENVIRONMENT INTERNATIONAL, 171 (107668). [PMID:36459822] |
| 2. Chun-Yang Li, Shi-Wen Lv, Lu Yang, Jin Wang, Jing-Min Liu, Shuo Wang. (2022) Facile preparation of uniform-sized covalent organic framework nanoflowers as versatile sample-pretreatment platforms for sensitive and specific determination of hazardous substances. JOURNAL OF HAZARDOUS MATERIALS, 438 (129566). [PMID:35999751] |
| 3. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu. (2022) 2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae. RESEARCH IN MICROBIOLOGY, 173 (103955). [PMID:35550403] |