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1,8-Dihydroxynaphthalene - ≥97%, high purity , CAS No.569-42-6

2 Citations
  • ≥97%
Item Number
D139008
Grouped product items
SKUSizeAvailabilityPrice Qty
D139008-1g
1g
In stock
$38.90
D139008-5g
5g
In stock
$173.90
D139008-25g
25g
In stock
$782.90
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Basic Description

SynonymsNaphthalene-1,8-diol | 1,8-Naphthalenediol | 569-42-6 | 1,8-Dihydroxynaphthalene | JEW2VB8R33 | MFCD00042701 | 138999-35-6 | EINECS 209-316-5 | 1,8-Naphthalindiol | 8-hydroxy-1-naphthol | 1-Hydroxy-8-naphthol | UNII-JEW2VB8R33 | SCHEMBL70219 | CHEMBL203537 | YSSJ3004 | 1,8-Dihydroxyna
Specifications & Purity≥97%
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Application：

1,8-Dihydroxynaphthalene (DHN) can be used as:
An intermediate in the preparation of benzo analogs of spiromamakone A.
A starting material to synthesize naphthopyran derivatives.
An intermediate in the total synthesis of palmarumycin CP17 analogs.


Associated Targets(Human)

ARG1 Tchem Arginase-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
T-24 (2342 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HFL1 (586 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ARG1 Arginase-1 (70 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name naphthalene-1,8-diol
INCHI InChI=1S/C10H8O2/c11-8-5-1-3-7-4-2-6-9(12)10(7)8/h1-6,11-12H
InChi Key OENHRRVNRZBNNS-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C(=C1)O)C(=CC=C2)O
Isomeric SMILES C1=CC2=C(C(=C1)O)C(=CC=C2)O
WGK Germany 3
PubChem CID 68438
Molecular Weight 160.17
Beilstein 2044947

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot NumberCertificate TypeDateItem
I2304416Certificate of AnalysisAug 09, 2023 D139008
I2304426Certificate of AnalysisAug 09, 2023 D139008
I2304427Certificate of AnalysisAug 09, 2023 D139008
I2304435Certificate of AnalysisAug 09, 2023 D139008
I2304436Certificate of AnalysisAug 09, 2023 D139008
I2304467Certificate of AnalysisAug 09, 2023 D139008

Chemical and Physical Properties

Melt Point(°C)137-143℃

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

WGK Germany 3

Related Documents

 SDS

 Specification Sheet

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Citations of This Product

1. Qing Li, Yujuan Guo, Meijia Wu, Fei Deng, Jieying Feng, Jiafeng Liu, Sheng Liu, Chaoliu Ouyang, Wengui Duan, Shunmin Yi, Guangfu Liao.  (2023)  Fluorinated Polyimide/Allomelanin Nanocomposites for UV-Shielding Applications.  MOLECULES,  28  (14): (5523).  [PMID:37513395]
2. Yajing Xiang, Xiaoliang Qi, Erya Cai, Chaofan Zhang, Jiajia Wang, Yulong Lan, Hui Deng, Jianliang Shen, Rongdang Hu.  (2023)  Highly efficient bacteria-infected diabetic wound healing employing a melanin-reinforced biopolymer hydrogel.  CHEMICAL ENGINEERING JOURNAL,  460  (141852).  [PMID:]

References

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2. R Romero-Martinez,M Wheeler,A Guerrero-Plata,G Rico,H Torres-Guerrero.  (2000-05-19)  Biosynthesis and functions of melanin in Sporothrix schenckii..  Infection and immunity,  68  ((6)): (3696-3703).  [PMID:10816530]
3. Jung-Kul Lee,Hyung-Moo Jung,Sang-Yong Kim.  (2003-06-06)  1,8-dihydroxynaphthalene (DHN)-melanin biosynthesis inhibitors increase erythritol production in Torula corallina, and DHN-melanin inhibits erythrose reductase..  Applied and environmental microbiology,  69  ((6)): (3427-3434).  [PMID:12788746]
4. C Ganesh Kumar,P Mongolla,S Pombala,A Kamle,J Joseph.  (2011-07-06)  Physicochemical characterization and antioxidant activity of melanin from a novel strain of Aspergillus bridgeri ICTF-201..  Letters in applied microbiology,  53  ((3)): (350-358).  [PMID:21726247]
5. Hong Jiang,Guang-Lei Liu,Zhe Chi,Jian-Ming Wang,Ly-Ly Zhang,Zhen-Ming Chi.  (2016-11-16)  Both a PKS and a PPTase are involved in melanin biosynthesis and regulation of Aureobasidium melanogenum XJ5-1 isolated from the Taklimakan desert..  Gene,  602  (8-15).  [PMID:27845206]
6. Bo Wang,Xiaofei Liang,Mark L Gleason,Rong Zhang,Guangyu Sun.  (2017-09-17)  Genome sequence of the ectophytic fungus Ramichloridium luteum reveals unique evolutionary adaptations to plant surface niche..  BMC genomics,  18  ((1)): (729-729).  [PMID:28915794]
7. Jeong-Joo Oh,Jee Young Kim,Sun Lul Kwon,Dong-Hyeok Hwang,Yoon-E Choi,Gyu-Hyeok Kim.  (2020-05-20)  Production and characterization of melanin pigments derived from Amorphotheca resinae..  Journal of microbiology (Seoul, Korea),  58  ((8)): (648-656).  [PMID:32424578]
8. Claudia Pacelli,Alessia Cassaro,Lorenzo Aureli,Ralf Moeller,Akira Fujimori,Silvano Onofri.  (2020-08-06)  The Responses of the Black Fungus Cryomyces Antarcticus to High Doses of Accelerated Helium Ions Radiation within Martian Regolith Simulants and Their Relevance for Mars..  Life (Basel, Switzerland),  10  ((8)):   [PMID:32752063]
9. E S Jacobson,E Hove,H S Emery.  (1995-12-01)  Antioxidant function of melanin in black fungi..  Infection and immunity,  63  ((12)): (4944-4945).  [PMID:7591162]
10. E Thines,H Anke,O Sterner.  (1998-06-19)  Scytalols A, B, C, and D and other modulators of melanin biosynthesis from Scytalidium sp. 36-93..  The Journal of antibiotics,  51  ((4)): (387-393).  [PMID:9630860]
11. A A Brakhage,K Langfelder,G Wanner,A Schmidt,B Jahn.  (1999-10-16)  Pigment biosynthesis and virulence..  Contributions to microbiology,  2  (205-215).  [PMID:10523276]
12. H F Tsai,I Fujii,A Watanabe,M H Wheeler,Y C Chang,Y Yasuoka,Y Ebizuka,K J Kwon-Chung.  (2001-05-15)  Pentaketide melanin biosynthesis in Aspergillus fumigatus requires chain-length shortening of a heptaketide precursor..  The Journal of biological chemistry,  276  ((31)): (29292-29298).  [PMID:11350964]
13. N A Yurlova,G S de Hoog,L G Fedorova.  (2008-01-01)  The influence of ortho- and para-diphenoloxidase substrates on pigment formation in black yeast-like fungi..  Studies in mycology,  61  (39-49).  [PMID:19287525]
14. Shao Yu Lin,Shiho Okuda,Kyoko Ikeda,Tetsuro Okuno,Yoshitaka Takano.  (2012-09-01)  LAC2 encoding a secreted laccase is involved in appressorial melanization and conidial pigmentation in Colletotrichum orbiculare..  Molecular plant-microbe interactions : MPMI,  25  ((12)): (1552-1561).  [PMID:22934563]
15. I Kutay Ozturk,Pranav Chettri,Pierre-Yves Dupont,Irene Barnes,Rebecca L McDougal,Geromy G Moore,Andre Sim,Rosie E Bradshaw.  (2017-07-12)  Evolution of polyketide synthesis in a Dothideomycete forest pathogen..  Fungal genetics and biology : FG & B,  106  (42-50).  [PMID:28690095]
16. Pham, et al..  (2020)  An intergenic safe haven region in Aspergillus fumigatus..  Medical Mycology,  58  (1178-1186).  [PMID:32171003]
17. Qing Li, Yujuan Guo, Meijia Wu, Fei Deng, Jieying Feng, Jiafeng Liu, Sheng Liu, Chaoliu Ouyang, Wengui Duan, Shunmin Yi, Guangfu Liao.  (2023)  Fluorinated Polyimide/Allomelanin Nanocomposites for UV-Shielding Applications.  MOLECULES,  28  (14): (5523).  [PMID:37513395]
18. Yajing Xiang, Xiaoliang Qi, Erya Cai, Chaofan Zhang, Jiajia Wang, Yulong Lan, Hui Deng, Jianliang Shen, Rongdang Hu.  (2023)  Highly efficient bacteria-infected diabetic wound healing employing a melanin-reinforced biopolymer hydrogel.  CHEMICAL ENGINEERING JOURNAL,  460  (141852).  [PMID:]

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