Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A122683-1g | 1g | In stock | $88.90 | |
A122683-5g | 5g | In stock | $397.90 | |
A122683-25g | 25g | In stock | $1,789.90 |
Synonyms | 1219805-83-0 | BDBM14320 | Nitriles, C10-16 | FT-0633643 | 1-amino isoquinoline | 1SQ | PD119379 | QUG12T52WZ | UNII-QUG12T52WZ | AC-907/25014244 | EN300-179397 | 2ohk | AM20050832 | aminoisoquinoline | isoquinolin-1-ylamine | isoquinolin-1-yl-amine | AKO |
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Specifications & Purity | ≥97% |
Storage Temp | Argon charged |
Shipped In | Normal |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488184797 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488184797 |
IUPAC Name | isoquinolin-1-amine |
INCHI | InChI=1S/C9H8N2/c10-9-8-4-2-1-3-7(8)5-6-11-9/h1-6H,(H2,10,11) |
InChi Key | OSILBMSORKFRTB-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C=CN=C2N |
Isomeric SMILES | C1=CC=C2C(=C1)C=CN=C2N |
WGK Germany | 3 |
PubChem CID | 73742 |
Molecular Weight | 144.17 |
Reaxy-Rn | 114480 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C2302172 | Certificate of Analysis | Mar 15, 2023 | A122683 |
C2302166 | Certificate of Analysis | Oct 25, 2022 | A122683 |
L2208220 | Certificate of Analysis | Oct 25, 2022 | A122683 |
L2208227 | Certificate of Analysis | Oct 25, 2022 | A122683 |
I1819083 | Certificate of Analysis | Jul 22, 2022 | A122683 |
I1418036 | Certificate of Analysis | Jul 11, 2022 | A122683 |
B1420034 | Certificate of Analysis | Feb 14, 2022 | A122683 |
Sensitivity | Air Sensitive |
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Boil Point(°C) | 166 °C/8 mmHg |
Melt Point(°C) | 122-124°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 114480 |
1. J B Rewinkel,H Lucas,P J van Galen,A B Noach,T G van Dinther,A M Rood,A J Jenneboer,C A van Boeckel. (1999-04-14) 1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors.. Bioorganic & medicinal chemistry letters, 9 ((5)): (685-690). [PMID:10201829] |
2. Cathleen Cover,Peter Fickert,Tamara R Knight,Andrea Fuchsbichler,Anwar Farhood,Michael Trauner,Hartmut Jaeschke. (2004-12-17) Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.. Toxicological sciences : an official journal of the Society of Toxicology, 84 ((1)): (201-208). [PMID:15601672] |
3. Miles Congreve,Gianni Chessari,Dominic Tisi,Andrew J Woodhead. (2008-05-07) Recent developments in fragment-based drug discovery.. Journal of medicinal chemistry, 51 ((13)): (3661-3680). [PMID:18457385] |
4. Danqing Zheng,Zhiyuan Chen,Jianping Liu,Jie Wu. (2011-05-28) An efficient route to 1-aminoisoquinolines via AgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine.. Organic & biomolecular chemistry, 9 ((13)): (4763-4765). [PMID:21617812] |
5. Xiaohong Wei,Miao Zhao,Zhengyin Du,Xingwei Li. (2011-08-05) Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling.. Organic letters, 13 ((17)): (4636-4639). [PMID:21812407] |
6. S Giorgi-Renault,J Renault,P Servolles. (1983-01-01) [A practical method for the synthesis of 1-aminoisoquinoline].. Annales pharmaceutiques francaises, 41 ((6)): (555-557). [PMID:6677167] |
7. Hervé Bibas,Daniel W J Moloney,Ralf Neumann,Majed Shtaiwi,Paul V Bernhardt,Curt Wentrup. (2002-04-13) Chemistry of stable iminopropadienones, RN=C=C=C=O.. The Journal of organic chemistry, 67 ((8)): (2619-2631). [PMID:11950308] |
8. Scott P Brown,Steven W Muchmore. (2009-04-24) Large-scale application of high-throughput molecular mechanics with Poisson-Boltzmann surface area for routine physics-based scoring of protein-ligand complexes.. Journal of medicinal chemistry, 52 ((10)): (3159-3165). [PMID:19385614] |
9. Adrian L Smith,Frenel F DeMorin,Nick A Paras,Qi Huang,Jeffrey K Petkus,Elizabeth M Doherty,Thomas Nixey,Joseph L Kim,Douglas A Whittington,Linda F Epstein,Matthew R Lee,Mark J Rose,Carol Babij,Manory Fernando,Kristen Hess,Quynh Le,Pedro Beltran,Josette Carnahan. (2009-09-22) Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.. Journal of medicinal chemistry, 52 ((20)): (6189-6192). [PMID:19764794] |