Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C153359-1g | 1g | In stock | $9.90 | |
C153359-5g | 5g | In stock | $34.90 | |
C153359-25g | 25g | In stock | $132.90 | |
C153359-100g | 100g | In stock | $277.90 | |
C153359-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,111.90 |
Anesthetic agent. Induces apoptosis and amyloid β-protein accumulation.
Synonyms | BBL100111 | SY050218 | A818554 | CAS-26675-46-7 | Isoflurano [INN-Spanish] | IsoSol | STL454337 | TerrellHSDB 8057 | C2485 | ISOFLURANE (EP MONOGRAPH) | CHEBI:6015 | HSDB-8057 | N01AB06 | NCGC00181037-02 | ATTANE | Compound 469 | Ethane, 2-chloro-2-(diflu |
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Specifications & Purity | Moligand™, ≥98%(GC) |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | ACTIVATOR, POSITIVE MODULATOR |
Mechanism of action | Potassium channel subfamily K member 2 opener |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Used only for R&D experiments |
ALogP | 2.1 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488179792 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179792 |
IUPAC Name | 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane |
INCHI | InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H |
InChi Key | PIWKPBJCKXDKJR-UHFFFAOYSA-N |
Canonical SMILES | C(C(F)(F)F)(OC(F)F)Cl |
Isomeric SMILES | C(C(F)(F)F)(OC(F)F)Cl |
RTECS | KN6799000 |
PubChem CID | 3763 |
Molecular Weight | 184.49 |
Reaxy-Rn | 1852087 |
PubChem CID | 3763 |
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ChEBI | CHEBI:6015 |
CAS Registry No. | 26675-46-7 |
ChEMBL Ligand | CHEMBL1256 |
DrugBank Ligand | DB00753 |
Wikipedia | Isoflurane |
PEP | isoflurane |
DrugCentral Ligand | 1493 |
PubChem SID | 488179792 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2404167 | Certificate of Analysis | Oct 24, 2024 | C153359 |
K2404166 | Certificate of Analysis | Oct 24, 2024 | C153359 |
K2404165 | Certificate of Analysis | Oct 24, 2024 | C153359 |
K2404153 | Certificate of Analysis | Oct 24, 2024 | C153359 |
K2404152 | Certificate of Analysis | Oct 24, 2024 | C153359 |
F2417168 | Certificate of Analysis | Jun 04, 2024 | C153359 |
F2417170 | Certificate of Analysis | Jun 04, 2024 | C153359 |
F2417169 | Certificate of Analysis | Jun 04, 2024 | C153359 |
F2417167 | Certificate of Analysis | Jun 04, 2024 | C153359 |
F2417166 | Certificate of Analysis | Jun 04, 2024 | C153359 |
F2417154 | Certificate of Analysis | Jun 04, 2024 | C153359 |
B2028066 | Certificate of Analysis | Dec 14, 2023 | C153359 |
C23101292 | Certificate of Analysis | Mar 22, 2023 | C153359 |
B2309276 | Certificate of Analysis | Feb 14, 2023 | C153359 |
B2309272 | Certificate of Analysis | Feb 14, 2023 | C153359 |
B2309305 | Certificate of Analysis | Feb 14, 2023 | C153359 |
I2220218 | Certificate of Analysis | Jul 20, 2022 | C153359 |
K2330172 | Certificate of Analysis | Jul 20, 2022 | C153359 |
I2220220 | Certificate of Analysis | Jul 20, 2022 | C153359 |
I2220219 | Certificate of Analysis | Jul 20, 2022 | C153359 |
I2220217 | Certificate of Analysis | Jul 20, 2022 | C153359 |
I2220216 | Certificate of Analysis | Jul 20, 2022 | C153359 |
C2414054 | Certificate of Analysis | Jul 20, 2022 | C153359 |
H1823083 | Certificate of Analysis | Jun 22, 2022 | C153359 |
F2307074 | Certificate of Analysis | Feb 23, 2022 | C153359 |
C2223485 | Certificate of Analysis | Feb 23, 2022 | C153359 |
C2223483 | Certificate of Analysis | Feb 23, 2022 | C153359 |
C2223492 | Certificate of Analysis | Feb 23, 2022 | C153359 |
C2223493 | Certificate of Analysis | Feb 23, 2022 | C153359 |
Solubility | Soluble in chloroform and ethyl acetate. Not miscible or difficult to mix in water. |
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Refractive Index | 1.302 |
Boil Point(°C) | 48-49℃ |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H373:Causes damage to organs through prolonged or repeated exposure H336:May cause drowsiness or dizziness |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P405:Store locked up. P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P319:Get medical help if you feel unwell. |
RTECS | KN6799000 |
Reaxy-Rn | 1852087 |
Merck Index | 5175 |
1. Shuanghui Lu, Xiu Chen, Yujia Chen, Yingqiong Zhang, Jun Luo, Huidi Jiang, Luo Fang, Hui Zhou. (2023) Downregulation of PDZK1 by TGF-β1 promotes renal fibrosis via inducing epithelial-mesenchymal transition of renal tubular cells. BIOCHEMICAL PHARMACOLOGY, (116015). [PMID:38158021] [10.1016/j.bcp.2023.116015] |
2. Ruiqing Zhou, Chengqing Huang, Nanxi Bi, Ling Li, Changqing Li, Xiaozhen Gu, Yang Song, Hui-Li Wang. (2023) Chronic Pb Exposure Induces Anxiety and Depression-like Behaviors in Mice via Excitatory Neuronal Hyperexcitability in Ventral Hippocampal Dentate Gyrus. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:37559393] [10.1021/acs.est.3c03426] |
3. Xiao Zhang, Yating Ma, Xiaojian Zhang, Xin Pang, Zhiheng Yang. (2023) Bio-inspired self-assembled bacteriochlorin nanoparticles for superior visualization and photothermal ablation of tumors. BIOMEDICINE & PHARMACOTHERAPY, 165 (115014). [PMID:37327585] [10.1016/j.biopha.2023.115014] |
4. Zhuang Kejin, Meng Weihong, Shu Xin, Liang Defu, Wang Lidong, Zhang Dongjie. (2023) Fecal metabonomics combined with 16S rDNA sequencing to analyze the changes of gut microbiota in rats fed with different protein source diets. EUROPEAN JOURNAL OF NUTRITION, 62 (6): (2687-2703). [PMID:37273002] [10.1007/s00394-023-03168-y] |
5. Rongrong Wang, Zhi-Hua Liu, Nanxi Bi, Xiaozhen Gu, Chengqing Huang, Ruiqing Zhou, Haoyu Liu, Hui-Li Wang. (2023) Dysfunction of the medial prefrontal cortex contributes to BPA-induced depression- and anxiety-like behavior in mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 259 (115034). [PMID:37210999] [10.1016/j.ecoenv.2023.115034] |
6. Haibo Du, Lianqin Ding, Tian Zeng, Di Li, Li Liu. (2022) LncRNA SNHG15 Modulates Ischemia-Reperfusion Injury in Human AC16 Cardiomyocytes Depending on the Regulation of the miR-335-3p/TLR4/NF-κB Pathway. International Heart Journal, 63 (3): (578-590). [PMID:] [10.1536/ihj.21-511] |
7. Wang Fei, Li Wu-lin, Shen Li-juan, Jiang Ting-ting, Xia Jian-jun, You Da-li, Hu Shan-you, Wang Li, Wu Xiao. (2022) Crocin Alleviates Intracerebral Hemorrhage–Induced Neuronal Ferroptosis by Facilitating Nrf2 Nuclear Translocation. NEUROTOXICITY RESEARCH, 40 (2): (596-604). [PMID:35380368] [10.1007/s12640-022-00500-y] |
8. Huang Yuxing, Deng Lisha, Zeng Lin, Bao Shanlin, Ye Kun, Li Chengxun, Hou Xiaolin, Yao Yuan, Li Dingjun, Xiong Zhen. (2021) Silencing of H19 alleviates oxygen–glucose deprivation/reoxygenation-triggered injury through the regulation of the miR-1306-5p/BCL2L13 axis. METABOLIC BRAIN DISEASE, 36 (8): (2461-2472). [PMID:34436746] [10.1007/s11011-021-00822-4] |
9. Haijuan Hu, Shanshan Zhang, Fengxia Liu, Peipei Zhang, Zafarullah Muhammad, Siyi Pan. (2019) Role of the Gut Microbiota and Their Metabolites in Modulating the Cholesterol-Lowering Effects of Citrus Pectin Oligosaccharides in C57BL/6 Mice. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (43): (11922–11930). [PMID:31576748] [10.1021/acs.jafc.9b03731] |
1. Wilson C et al.. (2020) Protocol for Evaluating Neuronal Polarity in Murine Models.. STAR Protoc, 1 (3): (100114). [PMID:33377010] |
2. Shuanghui Lu, Xiu Chen, Yujia Chen, Yingqiong Zhang, Jun Luo, Huidi Jiang, Luo Fang, Hui Zhou. (2023) Downregulation of PDZK1 by TGF-β1 promotes renal fibrosis via inducing epithelial-mesenchymal transition of renal tubular cells. BIOCHEMICAL PHARMACOLOGY, (116015). [PMID:38158021] [10.1016/j.bcp.2023.116015] |
3. Ruiqing Zhou, Chengqing Huang, Nanxi Bi, Ling Li, Changqing Li, Xiaozhen Gu, Yang Song, Hui-Li Wang. (2023) Chronic Pb Exposure Induces Anxiety and Depression-like Behaviors in Mice via Excitatory Neuronal Hyperexcitability in Ventral Hippocampal Dentate Gyrus. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:37559393] [10.1021/acs.est.3c03426] |
4. Xiao Zhang, Yating Ma, Xiaojian Zhang, Xin Pang, Zhiheng Yang. (2023) Bio-inspired self-assembled bacteriochlorin nanoparticles for superior visualization and photothermal ablation of tumors. BIOMEDICINE & PHARMACOTHERAPY, 165 (115014). [PMID:37327585] [10.1016/j.biopha.2023.115014] |
5. Zhuang Kejin, Meng Weihong, Shu Xin, Liang Defu, Wang Lidong, Zhang Dongjie. (2023) Fecal metabonomics combined with 16S rDNA sequencing to analyze the changes of gut microbiota in rats fed with different protein source diets. EUROPEAN JOURNAL OF NUTRITION, 62 (6): (2687-2703). [PMID:37273002] [10.1007/s00394-023-03168-y] |
6. Rongrong Wang, Zhi-Hua Liu, Nanxi Bi, Xiaozhen Gu, Chengqing Huang, Ruiqing Zhou, Haoyu Liu, Hui-Li Wang. (2023) Dysfunction of the medial prefrontal cortex contributes to BPA-induced depression- and anxiety-like behavior in mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 259 (115034). [PMID:37210999] [10.1016/j.ecoenv.2023.115034] |
7. Haibo Du, Lianqin Ding, Tian Zeng, Di Li, Li Liu. (2022) LncRNA SNHG15 Modulates Ischemia-Reperfusion Injury in Human AC16 Cardiomyocytes Depending on the Regulation of the miR-335-3p/TLR4/NF-κB Pathway. International Heart Journal, 63 (3): (578-590). [PMID:] [10.1536/ihj.21-511] |
8. Wang Fei, Li Wu-lin, Shen Li-juan, Jiang Ting-ting, Xia Jian-jun, You Da-li, Hu Shan-you, Wang Li, Wu Xiao. (2022) Crocin Alleviates Intracerebral Hemorrhage–Induced Neuronal Ferroptosis by Facilitating Nrf2 Nuclear Translocation. NEUROTOXICITY RESEARCH, 40 (2): (596-604). [PMID:35380368] [10.1007/s12640-022-00500-y] |
9. Huang Yuxing, Deng Lisha, Zeng Lin, Bao Shanlin, Ye Kun, Li Chengxun, Hou Xiaolin, Yao Yuan, Li Dingjun, Xiong Zhen. (2021) Silencing of H19 alleviates oxygen–glucose deprivation/reoxygenation-triggered injury through the regulation of the miR-1306-5p/BCL2L13 axis. METABOLIC BRAIN DISEASE, 36 (8): (2461-2472). [PMID:34436746] [10.1007/s11011-021-00822-4] |
10. Haijuan Hu, Shanshan Zhang, Fengxia Liu, Peipei Zhang, Zafarullah Muhammad, Siyi Pan. (2019) Role of the Gut Microbiota and Their Metabolites in Modulating the Cholesterol-Lowering Effects of Citrus Pectin Oligosaccharides in C57BL/6 Mice. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (43): (11922–11930). [PMID:31576748] [10.1021/acs.jafc.9b03731] |