1-Deoxymannojirimycin hydrochloride - 98%, high purity , CAS No.73465-43-7

Item Number

D115559

Grouped product items
SKU	Size	Availability	Price
D115559-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$52.90
D115559-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$216.90
D115559-10mg	10mg	In stock	$345.90
D115559-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$778.90

α-Mannosidase I inhibitor

Basic Description

Synonyms	1-Deoxymannojirimycin hydrochloride \| 73465-43-7 \| deoxymannojirimycin hydrochloride \| 1-Deoxymannojirimycin (hydrochloride) \| (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride \| 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Selective inhibitor ofα-mannosidase I.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Note	1mg卖完停产，不再备货
Product Description	1-Deoxymannojirimycin hydrochloride is a selective inhibitor of α(1→2)-mannosidases. Mannosidases are broken into two subtypes: I and II, which display a wide expression pattern. Mannosidase I hydrolyzes (1,2)-linked α-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2 and mannosidase II hydrolyzes (1,3)- and (1,6)-linked α-D-mannose residues in Man5(GlcNAc)3. Both mannosidase I and mannosidase II of require a divalent cation cofactor. 1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylationan and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity.

Names and Identifiers

IUPAC Name	(2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride
INCHI	InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4-,5-,6-;/m1./s1
InChi Key	ZJIHMALTJRDNQI-MVNLRXSJSA-N
Canonical SMILES	C1C(C(C(C(N1)CO)O)O)O.Cl
Isomeric SMILES	C1[C@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O.Cl
WGK Germany	3
PubChem CID	11390018
Molecular Weight	199.63

Certificates

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2 results found

Lot Number	Certificate Type	Date	Item
F1503015	Certificate of Analysis	Feb 13, 2023	D115559
D2422088	Certificate of Analysis	Nov 04, 2021	D115559

Solubility

Solvent:water, Max Conc. mg/mL: 9.98, Max Conc. mM: 50

Sensitivity

Air sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help.
WGK Germany	3

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Basic Description