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1-Deoxynojirimycin hydrochloride - 98%, high purity , CAS No.73285-50-4

  • ≥98%
Item Number
D487260
Grouped product items
SKUSizeAvailabilityPrice Qty
D487260-10mg
10mg
In stock
$68.90
D487260-50mg
50mg
In stock
$310.90
D487260-250mg
250mg
In stock
$1,397.90
D487260-1g
1g
In stock
$5,030.90
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Basic Description

Synonyms73285-50-4 | Duvoglustat hydrochloride | 1-Deoxynojirimycin hydrochloride | Duvoglustat HCl | Deoxynojirimycin hydrochloride | Moranoline hydrochloride | (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol hydrochloride | AT2220 | 1-Deoxy-L-altronojirimycin Hydrochlori
Specifications & Purity≥98%
Biochemical and Physiological Mechanisms1-Deoxynojirimycin (DNJ) is a naturally occurring alkaloid azasugar or iminosugar. It is observed in mulberry leaves, Commelina communis, and bacterial strains including Bacillus and Streptomyces species. DNJ acts as an α-glucosidase inhibitor and exhibit
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Description

Chemical structure: glucosamine



Application：

1-Deoxynojirimycin hydrochloride has been used

to study its effects on the loss-of-function of N-glycosylation pathway on hair cell regeneration

as an endoplasmic reticulum (ER) α-glucosidase I and II inhibitor to study its effects on TMED3-cystic fibrosis transmembrane conductance regulator (CFTR) interaction as an insect trehalase inhibitor in TREH inhibition bioassay


Product Properties

pKapKa: 13.77 (Predicted), pKa: 7.53 (Predicted)

Associated Targets(Human)

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CD69 Tchem Early activation antigen CD69 (107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Klrb1a Killer cell lectin-like receptor subfamily B member 1A (24 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488198333
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488198333
IUPAC Name (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride
INCHI InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5-,6-;/m1./s1
InChi Key ZJIHMALTJRDNQI-VFQQELCFSA-N
Canonical SMILES C1C(C(C(C(N1)CO)O)O)O.Cl
Isomeric SMILES C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O.Cl
WGK Germany 3
PubChem CID 13018787
Molecular Weight 199.63
Beilstein 3563225

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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7 results found

Lot NumberCertificate TypeDateItem
D2315805Certificate of AnalysisMar 10, 2023 D487260
D2315830Certificate of AnalysisMar 10, 2023 D487260
D2317155Certificate of AnalysisMar 10, 2023 D487260
D2317156Certificate of AnalysisMar 10, 2023 D487260
D2317159Certificate of AnalysisMar 10, 2023 D487260
D2317160Certificate of AnalysisMar 10, 2023 D487260
D2317165Certificate of AnalysisMar 10, 2023 D487260

Chemical and Physical Properties

Solubility water: 19.60-20.40mg/mL, clear, colorless
Melt Point(°C)208-210° C

Safety and Hazards(GHS)

WGK Germany 3
Merck Index 2.60069444444444

Related Documents

 SDS

 Specification Sheet

References

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