1-Formylpyrrolidine - 97%, high purity , CAS No.3760-54-1

  • ≥97%
Item Number
F469140
Grouped product items
SKUSizeAvailabilityPrice Qty
F469140-1g
1g
In stock
$9.90
F469140-5g
5g
In stock
$11.90
F469140-25g
25g
In stock
$49.90
F469140-100g
100g
In stock
$177.90

Basic Description

Synonyms1-(1-PHENYLCYCLOPROPYL)METHANAMINE | D83491 | F8884-0102 | NSC-42516 | Pyrrolidine-1-carbaldehyde | CS-0155290 | MFCD00003169 | AS-57240 | DTXSID40191042 | AMY24174 | EN300-1265854 | Z1255394997 | 1-Phenyl-cyclopropanecarbonitrile | CHEBI:178202 | 1-Formy
Specifications & Purity≥97%
Product Description

1-Formylpyrrolidine is the monomer constituent of gas clathrate inhibitor.1-Formylpyrrolidine was used in the synthesis of 1-oxa-3,4-dimethyl-5-(1-pyrrolldino)-2,2-di(tert-butyl)silacyclopentane and 1-oxa-4-isopropyl-5-(1-pyrrolidino)-2,2-di(tert-butyl)silacyclopentane.

Associated Targets(Human)

PPIB Tchem Peptidyl-prolyl cis-trans isomerase B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPIA Tclin Peptidyl-prolyl cis-trans isomerase A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPIB Tchem Cyclophilin B (53 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPIA Tclin Cyclophilin A (674 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488185399
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488185399
IUPAC Name pyrrolidine-1-carbaldehyde
INCHI InChI=1S/C5H9NO/c7-5-6-3-1-2-4-6/h5H,1-4H2
InChi Key AGRIQBHIKABLPJ-UHFFFAOYSA-N
Canonical SMILES C1CCN(C1)C=O
Isomeric SMILES C1CCN(C1)C=O
WGK Germany 3
PubChem CID 77372
Molecular Weight 99.13

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
F23161328Certificate of AnalysisMay 25, 2023 F469140
F23161331Certificate of AnalysisMay 25, 2023 F469140
F23161332Certificate of AnalysisMay 25, 2023 F469140
F23161333Certificate of AnalysisMay 25, 2023 F469140
F23161334Certificate of AnalysisMay 25, 2023 F469140
F23161335Certificate of AnalysisMay 25, 2023 F469140
F23161337Certificate of AnalysisMay 25, 2023 F469140
F23161344Certificate of AnalysisMay 25, 2023 F469140

Chemical and Physical Properties

Refractive Index1.479 (lit.)
Flash Point(°F)203 °F
Flash Point(°C)95 °C
Boil Point(°C)92-94 °C/15 mmHg (lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

References

1. M Saito,M Hashimoto,N Kawaguchi,H Fukami,T Tanaka,N Higuchi.  (1990-01-01)  Synthesis and inhibitory activity of acyl-peptidyl-prolinalderivatives toward post-proline cleaving enzyme as nootropic agents..  Journal of enzyme inhibition,  ((3)): (163-178).  [PMID:2079633]
2. Y Tanaka,S Niwa,H Nishioka,T Yamanaka,M Torizuka,K Yoshinaga,N Kobayashi,Y Ikeda,H Arai.  (1994-06-24)  New potent prolyl endopeptidase inhibitors: synthesis and structure-activity relationships of indan and tetralin derivatives and their analogues..  Journal of medicinal chemistry,  37  ((13)): (2071-2078).  [PMID:8027988]
3. Joseph Bejjani,Fabrice Chemla,Max Audouin.  (2003-12-06)  N-tritylprolinal: an efficient building block for the stereoselective synthesis of proline-derived amino alcohols..  The Journal of organic chemistry,  68  ((25)): (9747-9752).  [PMID:14656102]
4. Marco Pallavicini,Barbara Moroni,Cristiano Bolchi,Francesco Clementi,Laura Fumagalli,Cecilia Gotti,Silvia Vailati,Ermanno Valoti,Luigi Villa.  (2004-10-27)  Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers..  Bioorganic & medicinal chemistry letters,  14  ((23)): (5827-5830).  [PMID:15501049]
5. Franck Sobrio,Thomas Quentin,Martine Dhilly,Thomas Bourdier,Sylvie Tymciu,Danièle Debruyne,Louisa Barré.  (2008-03-22)  Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for beta4 selective subtype nicotinic acetylcholine receptor..  Nuclear medicine and biology,  35  ((3)): (377-385).  [PMID:18355694]
6. Peter H Huy,Isabel Filbrich.  (2018-03-07)  A General Catalytic Method for Highly Cost- and Atom-Efficient Nucleophilic Substitutions..  Chemistry (Weinheim an der Bergstrasse, Germany),  24  ((29)): (7410-7416).  [PMID:29508466]
7. Peter H Huy,Christelle Mbouhom.  (2019-09-07)  Formamide catalyzed activation of carboxylic acids - versatile and cost-efficient amidation and esterification..  Chemical science,  10  ((31)): (7399-7406).  [PMID:31489162]
8. M Nanri,H Kaneto.  (1987-06-01)  [Anti-amnesic effect of prolyl endopeptidase inhibitors in mice]..  Nihon yakurigaku zasshi. Folia pharmacologica Japonica,  89  ((6)): (323-329).  [PMID:3305244]
9. L Frick,R Wolfenden.  (1985-07-01)  Mechanistic implications of the inhibition of peptidases by amino aldehydes and bestatin..  Biochimica et biophysica acta,  829  ((3)): (311-318).  [PMID:3890953]
10. T Yoshimoto,K Kawahara,F Matsubara,K Kado,D Tsuru.  (1985-10-01)  Comparison of inhibitory effects of prolinal-containing peptide derivatives on prolyl endopeptidases from bovine brain and Flavobacterium..  Journal of biochemistry,  98  ((4)): (975-979).  [PMID:3908451]
11. Roser Pons,Mercedes Serrano,Aida Ormazabal,Claudio Toma,Angels Garcia-Cazorla,Estela Area,Marta Ribasés,Emmanuel Kanavakis,Kaliopi Drakaki,Aristotelis Giannakopoulos,Irene Orfanou,Sotiris Youroukos,Bru Cormand,Rafael Artuch.  (2010-03-04)  Tyrosine hydroxylase deficiency in three Greek patients with a common ancestral mutation..  Movement disorders : official journal of the Movement Disorder Society,  25  ((8)): (1086-1090).  [PMID:20198643]
12. Manjusha M Kulkarni,Anna Karafova,Wojciech Kamysz,Sergio Schenkman,Roger Pelle,Bradford S McGwire.  (2013-02-07)  Secreted trypanosome cyclophilin inactivates lytic insect defense peptides and induces parasite calcineurin activation and infectivity..  The Journal of biological chemistry,  288  ((12)): (8772-8784).  [PMID:23386612]

Solution Calculators