Basic Description

Synonyms	1-Methyl-DL-tryptophan \| 26988-72-7 \| 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid \| 1-Methyltryptophan \| (Rac)-Indoximod \| 2-amino-3-(1-methylindol-3-yl)propanoic acid \| N-methyl-DL-tryptophan \| CHEBI:72821 \| 1-methyl-tryptophan \| tryptophan, 1-methyl- \| DL-1-Methyltryp
Specifications & Purity	Moligand™, ≥97%
Storage Temp	Room temperature
Shipped In	Normal
Grade	Moligand™
Product Description	application： 1-Methyl-DL-tryptophan, a competitive inhibitor of indoleamine 2,3 dioxygenase-1 (IDO1), has been used to study inflammation-induced depression in mice and syncytial virus induced bronchiolitis.

Associated Targets(Human)

IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)

Discover Target: IDO1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ftmPT1 Brevianamide F prenyltransferase (40 Activities)

Discover Target: ftmPT1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488187106
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488187106
IUPAC Name	2-amino-3-(1-methylindol-3-yl)propanoic acid
INCHI	InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)
InChi Key	ZADWXFSZEAPBJS-UHFFFAOYSA-N
Canonical SMILES	CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N
Isomeric SMILES	CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N
WGK Germany	3
Alternate CAS	26988-72-7,21339-55-9
PubChem CID	98112
NSC Number	77678
MeSH Entry Terms	1-methyl-DL-Trp;1-methyltryptophan;indoximod
Molecular Weight	218.25

Database links

PubChem SID	488187106

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
B2308870	Certificate of Analysis	Nov 25, 2022	M169177
B2308874	Certificate of Analysis	Nov 25, 2022	M169177
B2308917	Certificate of Analysis	Nov 25, 2022	M169177
B2308920	Certificate of Analysis	Nov 25, 2022	M169177
B2308936	Certificate of Analysis	Nov 25, 2022	M169177

Chemical and Physical Properties

Melt Point(°C)	250℃ (dec.) (lit.)

Safety and Hazards(GHS)

WGK Germany	3

Citations of This Product

1. Shikai Zhang, Qing Xu, Changbo Ji, Xiaoyu Han, Yang Zhou, Chao Liang, Linran Ma, Weijian Sun, Yanling Li, Zhengyou Yang, Fengchun Zhao, Yuan Tian. (2023) Study on secondary metabolites of endophytic fungus Diaporthe sp. AC1 induced by tryptophan analogs. Frontiers in Microbiology, 14 (1): (1254609). [PMID:37876783]

References

1. Shikai Zhang, Qing Xu, Changbo Ji, Xiaoyu Han, Yang Zhou, Chao Liang, Linran Ma, Weijian Sun, Yanling Li, Zhengyou Yang, Fengchun Zhao, Yuan Tian. (2023) Study on secondary metabolites of endophytic fungus Diaporthe sp. AC1 induced by tryptophan analogs. Frontiers in Microbiology, 14 (1): (1254609). [PMID:37876783]

Solution Calculators

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SKU	Size	Availability	Price
M169177-250mg	250mg	In stock	$103.90
M169177-1g	1g	In stock	$293.90
M169177-5g	5g	In stock	$1,320.90

1-Methyl-DL-tryptophan - 97%, high purity , CAS No.26988-72-7