Skip to the beginning of the images gallery

1-Oleoyl lysophosphatidic acid - ≥95%，10mg/ml in ethanol, high purity , CAS No.65528-98-5

≥95%，10mg/ml in ethanol

CAS#: 65528-98-5
Formula: C₂₁H₄₁O₇P
Molecular Weight: 436.52
PubChem CID: 5311263

Item Number

O353308

Grouped product items
SKU	Size	Availability	Price
O353308-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$79.90
O353308-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$319.90
O353308-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$499.90

a species of lysophosphatidic acid containing oleic acid at the sn-1 position

View related series

GPCR/G Protein LPL Receptor

Basic Description

Synonyms	1-Oleoyl Lysophosphatidic Acid\|1-Oleoyl-sn-glycerol 3-phosphate\|65528-98-5\|lysophosphatidic acid\|1-Oleoyl-sn-glycero-3-phosphate\|CHEBI:62837\|1-(9Z-octadecenoyl)-sn-glycero-3-phosphate\|PA(18:1/0:0)\|LysoPA(18:1)\|1-oleylglycerol 3-phosphate\|1-oleoylglycerol
Specifications & Purity	≥95%，10mg/ml in ethanol
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is made either through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) follow by phosphorylation of DAG by diglycerol kinase or directly through the action of phospholipase D (PLD). Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA, which binds to one of five different G protein linked receptors to mediate a variety of biological responses including platelet aggregation, cell proliferation, smooth muscle contraction, cell motility and neurite retraction. 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.

pKa

pKₐ: 1.82 (Predicted)

Ki Data

Autotaxin: Ki= 100 nM (human)

Associated Targets

ENPP2 Tchem Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3 Activities

Discover Target: ENPP2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPV1 Tclin Transient receptor potential cation channel subfamily V member 1 1 Activities

Discover Target: TRPV1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR4 Tchem Lysophosphatidic acid receptor 4 2 Activities

Discover Target: LPAR4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR3 Tchem Lysophosphatidic acid receptor 3 2 Activities

Discover Target: LPAR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR1 Tchem Lysophosphatidic acid receptor 1 5 Activities

Discover Target: LPAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR5 Tchem Lysophosphatidic acid receptor 5 3 Activities

Discover Target: LPAR5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR6 Tchem Lysophosphatidic acid receptor 6 0 Activities

Discover Target: LPAR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR2 Tchem Lysophosphatidic acid receptor 2 4 Activities

Discover Target: LPAR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	[(2R)-2-hydroxy-3-phosphonooxypropyl] (Z)-octadec-9-enoate
INCHI	InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1
InChi Key	WRGQSWVCFNIUNZ-GDCKJWNLSA-N
Canonical SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O
Isomeric SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)(O)O)O
PubChem CID	5311263
UN Number	1170
Packing Group	II
Molecular Weight	436.52

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot Number	Certificate Type	Date	Item
G2415512	Certificate of Analysis	Jul 02, 2024	O353308
G2415514	Certificate of Analysis	Jul 02, 2024	O353308
G2415517	Certificate of Analysis	Jul 02, 2024	O353308
G2415519	Certificate of Analysis	Jul 02, 2024	O353308
H2203639	Certificate of Analysis	Jun 25, 2022	O353308
H2203640	Certificate of Analysis	Jun 25, 2022	O353308
H2204022	Certificate of Analysis	Jun 25, 2022	O353308
H2328035	Certificate of Analysis	Jun 25, 2022	O353308

Solubility

Soluble in DMSO (~2 mg/ml), DMF (~2 mg/ml), PBS (pH 7.2) (~3 mg/ml), and ethanol.

Refractive Index

n20D1.49 (Predicted)

Boil Point(°C)

78° C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS02
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H225:Highly Flammable liquid and vapor
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P337+P313:IF eye irritation persists: Get medical advice/attention. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.
Class	3

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.