1-Stearoyl-2-arachidonoyl-sn-glycerol - 95%,25mg/ml in methyl acetate, high purity , CAS No.65914-84-3, Activator of TRPC6

Item Number
S347974
Grouped product items
SKUSizeAvailabilityPrice Qty
S347974-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$88.90
S347974-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$135.90

a diacylglycerol derivative and activator of PKC

Basic Description

SynonymsDG(18:0/20:4(omega-6)/0:0) | DG(18:0/20:4omega6) | (2S)-1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate | DTXSID80178317 | GTPL2437 | HY-131897 | SCHEMBL3504222 | BSPBio_001407 | CHEBI:75728 | 5,8,11,14-Eicosatetraenoi
Specifications & PurityMoligand™, ≥95%, 25mg/ml in methyl acetate
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeACTIVATOR
Mechanism of actionActivator of TRPC6
NoteStore, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 2 months.
Product Description

1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol derivative, and an endogenous activator of PKC (protein kinase C). 1-Stearoyl-2-arachidonoyl-sn-glycerol is produced via receptor-mediated inositol phospholipid hydrolysis. 1-Stearoyl-2-arachidonoyl-sn-glycerol is an activator of PKCβ, PKCε and PKCα.

Associated Targets(Human)

TRPC6 Tchem Short transient receptor potential channel 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [(2S)-1-hydroxy-3-octadecanoyloxypropan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
INCHI InChI=1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3/b13-11-,19-17-,24-22-,30-28-/t39-/m0/s1
InChi Key NSXLMTYRMFVYNT-IUJDHQGTSA-N
Canonical SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC
Isomeric SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC
WGK Germany 3
PubChem CID 6438587
Molecular Weight 645.01
Beilstein 2198923

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
A2329180Certificate of AnalysisNov 09, 2022 S347974
A2329187Certificate of AnalysisNov 09, 2022 S347974

Chemical and Physical Properties

SolubilitySoluble in DMSO (5 mg/ml), 100% ethanol, water (partly miscible), and chloroform (20 mg/ml).
Refractive Indexn20D1.49 (Predicted)
Boil Point(°C)689.18° C at 760 mmHg (Predicted)

Safety and Hazards(GHS)

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

Solution Calculators