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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S347974-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $88.90 | |
S347974-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $135.90 |
a diacylglycerol derivative and activator of PKC
Synonyms | DG(18:0/20:4(omega-6)/0:0) | DG(18:0/20:4omega6) | (2S)-1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate | DTXSID80178317 | GTPL2437 | HY-131897 | SCHEMBL3504222 | BSPBio_001407 | CHEBI:75728 | 5,8,11,14-Eicosatetraenoi |
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Specifications & Purity | Moligand™, ≥95%, 25mg/ml in methyl acetate |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ACTIVATOR |
Mechanism of action | Activator of TRPC6 |
Note | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 2 months. |
Product Description | 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol derivative, and an endogenous activator of PKC (protein kinase C). 1-Stearoyl-2-arachidonoyl-sn-glycerol is produced via receptor-mediated inositol phospholipid hydrolysis. 1-Stearoyl-2-arachidonoyl-sn-glycerol is an activator of PKCβ, PKCε and PKCα. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | [(2S)-1-hydroxy-3-octadecanoyloxypropan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate |
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INCHI | InChI=1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3/b13-11-,19-17-,24-22-,30-28-/t39-/m0/s1 |
InChi Key | NSXLMTYRMFVYNT-IUJDHQGTSA-N |
Canonical SMILES | CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC |
Isomeric SMILES | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC |
WGK Germany | 3 |
PubChem CID | 6438587 |
Molecular Weight | 645.01 |
Beilstein | 2198923 |
PubChem CID | 6438587 |
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ChEBI | CHEBI:75728 |
CAS Registry No. | 65914-84-3 |
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Solubility | Soluble in DMSO (5 mg/ml), 100% ethanol, water (partly miscible), and chloroform (20 mg/ml). |
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Refractive Index | n20D1.49 (Predicted) |
Boil Point(°C) | 689.18° C at 760 mmHg (Predicted) |
WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |