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10,11-Dehydrocurvularin - ≥99.0%, high purity , CAS No.21178-57-4

≥99%

CAS#: 21178-57-4
Formula: C₁₆H₁₈O₅
Molecular Weight: 290.31
PubChem CID: 6438143

Item Number

D651222

Grouped product items
SKU	Size	Availability	Price	Qty
D651222-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$500.90
D651222-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,200.90

Antibiotics Disease Research Anticancer Phenols Polyphenols Antibiotics Macrolide Antibiotics

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Antibiotics Disease Research Anticancer Phenols Polyphenols Antibiotics Macrolide Antibiotics Cell Cycle/DNA Damage HSP Metabolic Enzyme/Protease Stem Cell/Wnt TGF-beta/Smad

Basic Description

Synonyms	UNII-PAU7YA7FF9 \| (10E,15S)-10(11)-Dehydrocurvularin \| SCHEMBL23515579 \| MLS004257368 \| Trans-Dehydrocurvularin \| CS-0132763 \| 4,5,6,7-Tetrahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10-(1H)-dione \| BDBM50587861 \| 2H-3-Benzoxacyclododecin-2
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic . 10,11-Dehydrocurvularin is a strong activator of the heat shock response . 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity. Form:Solid

Associated Targets(Human)

DU-145 (51482 Activities)

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Huh-7 (12904 Activities)

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K562 (73714 Activities)

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MCF7 (126967 Activities)

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U-937 (7138 Activities)

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MIA PaCa-2 (5949 Activities)

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NCI-H460 (60772 Activities)

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SF-268 (49410 Activities)

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Jurkat (10389 Activities)

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HeLa (62764 Activities)

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MDA-MB-231 (73002 Activities)

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VCP Tchem Transitional endoplasmic reticulum ATPase (895 Activities)

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SW1990 (722 Activities)

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PC-3M (435 Activities)

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Associated Targets(non-human)

Trypanosoma brucei brucei (13300 Activities)

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Hsf1 Heat shock factor protein 1 (5445 Activities)

Discover Target: Hsf1

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Names and Identifiers

IUPAC Name	(5S,9E)-13,15-dihydroxy-5-methyl-4-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraene-3,11-dione
INCHI	InChI=1S/C16H18O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h4,6-7,9-10,17,19H,2-3,5,8H2,1H3/b6-4+/t10-/m0/s1
InChi Key	AVIRMQMUBGNCKS-RWCYGVJQSA-N
Canonical SMILES	CC1CCCC=CC(=O)C2=C(CC(=O)O1)C=C(C=C2O)O
Isomeric SMILES	C[C@H]1CCC/C=C/C(=O)C2=C(CC(=O)O1)C=C(C=C2O)O
PubChem CID	6438143
Molecular Weight	290.31

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10,11-Dehydrocurvularin - ≥99.0%, high purity , CAS No.21178-57-4

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

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