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12-OxoETE - 100 ug/mL in ethanol，≥90%, high purity , CAS No.108437-64-5

100 ug/mL in ethanol，≥90%

CAS#: 108437-64-5
Formula: C₂₀H₃₀O₃
Molecular Weight: 318.5
PubChem CID: 5283162

Item Number

O348448

Grouped product items
SKU	Size	Availability	Price	Qty
O348448-25μg	25μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$203.90
O348448-50μg	50μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$385.90

a compound produced from arachidonic acid

Basic Description

Synonyms	12-oxo-ETE \| 12-OxoETE \| 12-KETE \| 108437-64-5 \| 12-oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid \| CHEBI:34151 \| (5Z,8Z,10E,14Z)-12-Oxoicosa-5,8,10,14-tetraenoic acid \| CHEMBL3310737 \| (5Z,8Z,10E,14Z)-12-Oxoeicosa-5,8,10,14-tetraenoic acid \| (5Z,8Z,10E,14Z)-12-Oxoicosa-5,8,10,1
Specifications & Purity	100 ug/mL in ethanol，≥90%
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	12-OxoETE is synthesized by human platelets and\|Aplysia\|nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via an Leukotriene B4 receptor or a common activation sequence.

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

Discover Target: ALOX15B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)

Discover Target: ALOX12

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(5Z,8Z,10E,14Z)-12-oxoicosa-5,8,10,14-tetraenoic acid
INCHI	InChI=1S/C20H30O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+
InChi Key	GURBRQGDZZKITB-VXBMJZGYSA-N
Canonical SMILES	CCCCCC=CCC(=O)C=CC=CCC=CCCCC(=O)O
Isomeric SMILES	CCCCC/C=C\CC(=O)/C=C/C=C\C/C=C\CCCC(=O)O
PubChem CID	5283162
Molecular Weight	318.5

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2 results found

Lot Number	Certificate Type	Date	Item
H2229682	Certificate of Analysis	Aug 04, 2022	O348448
H2229691	Certificate of Analysis	Aug 04, 2022	O348448

Solubility

Soluble in water (0.8 mg/ml at 25° C), ethanol, DMSO, DMF, and PBS pH 7.2, sol. (~0.8).

Refractive Index

n20D1.51 (Predicted)

Boil Point(°C)

78° C

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