13-APA , CAS No.71629-07-7

Item Number
A335533
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A335533-1mg
1mg
Available within 8-12 weeks(?)
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$61.90
A335533-10mg
10mg
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$512.90

a specific thromboxane A2 receptor (TP) antagonist

Basic Description

Synonyms13-azaprostanoic acid | 71629-07-7 | 7-[(1s,2s)-2-(heptylamino)cyclopentyl]heptanoic acid | 7-((1S,2S)-2-(Heptylamino)cyclopentyl)heptanoic acid | (+/-)13-AZAPROSTANOIC ACID | (+-)-13-AZAPROSTANOIC ACID | CHEMBL9811 | CBiol_001997 | 13-APA | BML1-G10 | SCHEMBL7719993 | DTXSID8
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

13-APA is a moderately potent, yet specific TXA2R (thromboxane A2 receptor, TP) antagonist.1 13-APA is more selective (5-fold) for the platelet (human) versus vascular (rat) TP receptor2–5.

Associated Targets(Human)

PTGS1 Tclin Prostaglandin G/H synthase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Cyclooxygenase (1258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 7-[(1S,2S)-2-(heptylamino)cyclopentyl]heptanoic acid
INCHI InChI=1S/C19H37NO2/c1-2-3-4-7-10-16-20-18-14-11-13-17(18)12-8-5-6-9-15-19(21)22/h17-18,20H,2-16H2,1H3,(H,21,22)/t17-,18-/m0/s1
InChi Key RZZNGDIYQSCFGK-ROUUACIJSA-N
Canonical SMILES CCCCCCCNC1CCCC1CCCCCCC(=O)O
Isomeric SMILES CCCCCCCN[C@H]1CCC[C@@H]1CCCCCCC(=O)O
WGK Germany 3
PubChem CID 123640
Molecular Weight 311.5

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in ethanol (10 mg/ml).

Safety and Hazards(GHS)

WGK Germany 3

Related Documents

Solution Calculators