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13-OxoODE - 95%,100 ug/mL in ethanol, high purity , CAS No.54739-30-9
a stimulator of cell proliferation
Basic Description Synonyms 13-OxoODE | 13-OXO-ODE | 13-keto-9Z,11E-octadecadienoic acid | BDBM50045522 | PD020944 | 4-Amino-2-sulphodiphenylamine | 13-KODE | NCGC00161271-03 | 13-Oxo-9Z,11E-octadecadienoic acid | HMS1791C15 | JHXAZBBVQSRKJR-BSZOFBHHSA-N | 13-ketooctadecadienoic aci Specifications & Purity ≥95%, 100 ug/mL in ethanol Storage Temp Protected from light,Store at -80°C Shipped In Ice chest + Ice pads Product Description 13-OxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa.1 Stimulates cell proliferation when instilled intrarectally in rats.2 Has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes through the activity of 15-LO. 13-OxoODE is an activator of PPAR α(peroxisome proliferator-activated receptor α).
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (9Z,11E)-13-oxooctadeca-9,11-dienoic acid INCHI InChI=1S/C18H30O3/c1-2-3-11-14-17(19)15-12-9-7-5-4-6-8-10-13-16-18(20)21/h7,9,12,15H,2-6,8,10-11,13-14,16H2,1H3,(H,20,21)/b9-7-,15-12+ InChi Key JHXAZBBVQSRKJR-BSZOFBHHSA-N Canonical SMILES CCCCCC(=O)C=CC=CCCCCCCCC(=O)O Isomeric SMILES CCCCCC(=O)/C=C/C=C\CCCCCCCC(=O)O RTECS RG0180250 PubChem CID 6446027 Molecular Weight 294.43
Chemical and Physical Properties Solubility Soluble in water (>1 mg/ml at 25° C), ethanol, DMSO (~50 mg/ml), DMF (~50 mg/ml), and PBS (pH 7.2) (~1 mg/ml). Sensitivity light sensitive;Hygroscopic Refractive Index n20D~1.48 Boil Point(°C) 78° C
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