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Home Bioactive Small Molecules 15-KETE (15-oxo-ETE) - 50μg size: 50 μg/ml in ethanol 1mg size: 1mg/ml in ethanol, high purity , CAS No.81416-72-0
15-KETE (15-oxo-ETE) - 50μg size: 50 μg/ml in ethanol 1mg size: 1mg/ml in ethanol, high purity , CAS No.81416-72-0
a major metabolite of arachidonic acid that is formed through the Lipoxygenase pathway
Basic Description Synonyms (5Z,8Z,11Z,13E)-15-oxoeicosa-5,8,11,13-tetraenoic acid | C04577 | NCGC00161270-02 | (5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid | LMFA03060051 | 15-Oxo-5,8,11-cis-13-trans-icosatetraenoic acid | 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate | CHE Specifications & Purity 50μg size: 50 μg/ml in ethanol 1mg size: 1mg/ml in ethanol Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description 15-KETE is a major metabolite of arachidonic acid that is formed through the Lipoxygenase pathway in interleukin-4 treated human cord blood derived mast cells. 15-HPETE is enzymatically transformed into 15-KETE from homolytic cleavage of the O-O bond. It has also been found to be a product of the oxidation of 15-HETE by lunch prostaglandin dehydrogenase. In mouse liver, 15-hydroxyeicostatetraenoic acid is found to convert into 15-KETE.
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid INCHI InChI=1S/C20H30O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-5,8-11,14,17H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14+ InChi Key YGJTUEISKATQSM-USWFWKISSA-N Canonical SMILES CCCCCC(=O)C=CC=CCC=CCC=CCCCC(=O)O Isomeric SMILES CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O PubChem CID 5280701 Molecular Weight 318.45
Chemical and Physical Properties Solubility Soluble in water (0.8 mg/ml) at 25° C, DMSO, DMF, acetonitrile, EtOH, and PBS pH7.2. Refractive Index n20D1.51 Boil Point(°C) 78° C
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