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15-KETE (15-oxo-ETE) - 50μg size: 50 μg/ml in ethanol 1mg size: 1mg/ml in ethanol, high purity , CAS No.81416-72-0

  • 50μg size: 50 μg/ml in ethanol 1mg size: 1mg/ml in ethanol
Item Number
K336033
Grouped product items
SKUSizeAvailabilityPrice Qty
K336033-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$171.90
K336033-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,780.90
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a major metabolite of arachidonic acid that is formed through the Lipoxygenase pathway

Basic Description

Synonyms15-OxoETE | 15-Oxo-ETE | (5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid | 81416-72-0 | 15-Kete | 15-Keto-5,8,11,13-eicosatetraenoic acid | 15-oxo-5Z,8Z,11Z,13E-eicosatetraenoic acid | 15-ketoeicosatetraenoic acid | CHEMBL418941 | CHEBI:15559 | 15-Oxo-5,8,11-cis-13-tra
Specifications & Purity50μg size: 50 μg/ml in ethanol 1mg size: 1mg/ml in ethanol
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

15-KETE is a major metabolite of arachidonic acid that is formed through the Lipoxygenase pathway in interleukin-4 treated human cord blood derived mast cells. 15-HPETE is enzymatically transformed into 15-KETE from homolytic cleavage of the O-O bond. It has also been found to be a product of the oxidation of 15-HETE by lunch prostaglandin dehydrogenase. In mouse liver, 15-hydroxyeicostatetraenoic acid is found to convert into 15-KETE.

Product Properties

pKapKa: 4.75

Associated Targets(Human)

ALOX12 Tchem Arachidonate 12-lipoxygenase, 12S-type (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid
INCHI InChI=1S/C20H30O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-5,8-11,14,17H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14+
InChi Key YGJTUEISKATQSM-USWFWKISSA-N
Canonical SMILES CCCCCC(=O)C=CC=CCC=CCC=CCCCC(=O)O
Isomeric SMILES CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O
PubChem CID 5280701
Molecular Weight 318.45

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water (0.8 mg/ml) at 25° C, DMSO, DMF, acetonitrile, EtOH, and PBS pH7.2.
Refractive Indexn20D1.51
Boil Point(°C)78° C

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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