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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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H275088-50μg | 50μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $229.90 |
Prostacyclin synthase inhibitor
Synonyms | 15-HYDROPEROXYEICOSATETRAENOIC ACID, (5Z,8Z,11Z,13E,15S)- | DTXSID301318203 | 15(S)-HpETE Lipid Maps(R) MS Standard | SCHEMBL4329512 | BDBM50025742 | NCGC00161251-02 | UNII-7BN3O939P6 | (5Z,8Z,11Z,13E)-(15S)-15-Hydroperoxyicosa-5,8,11,13-tetraenoic acid | |
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Specifications & Purity | Moligand™, ≥95%, A solution in ethanol |
Biochemical and Physiological Mechanisms | Prostacyclin synthase inhibitor. In vivo and in vitro use. Lipoxygenase pathway. Inhibits platelet aggregation. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -80°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | A solution in ethanol. To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (5Z,8Z,11Z,13E,15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoic acid |
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INCHI | InChI=1S/C20H32O4/c1-2-3-13-16-19(24-23)17-14-11-9-7-5-4-6-8-10-12-15-18-20(21)22/h4-5,8-11,14,17,19,23H,2-3,6-7,12-13,15-16,18H2,1H3,(H,21,22)/b5-4-,10-8-,11-9-,17-14+/t19-/m0/s1 |
InChi Key | BFWYTORDSFIVKP-VAEKSGALSA-N |
Canonical SMILES | CCCCCC(C=CC=CCC=CCC=CCCCC(=O)O)OO |
Isomeric SMILES | CCCCC[C@@H](/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O)OO |
PubChem CID | 5280893 |
Molecular Weight | 336.47 |
PubChem CID | 5280893 |
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BindingDB Ligand | 50025742 |
ChEBI | CHEBI:15628 |
CAS Registry No. | 70981-96-3 |
ChEMBL Ligand | CHEMBL1606580 |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
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