16α-Hydroxy Progesterone - 98%, high purity , CAS No.438-07-3

  • ≥98%
Item Number
H336075
Grouped product items
SKUSizeAvailabilityPrice Qty
H336075-5mg
5mg
In stock
$74.90
H336075-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$285.90

a human progesterone receptors hPR-A and hPR-B agonist

Basic Description

Synonyms16a-hydroxyprogesterone | Pregn-4-ene-3, 16.alpha.-hydroxy- | Pregn-4-ene-3,20-dione, 16.alpha.-hydroxy- | Pregn-4-ene-3, 16-hydroxy-, (16.alpha.)- | NSC 523249 | SMR000457347 | UNII-Y7JT9A46EO | 16alpha-hydroxyprogesterone1 | DTXSID001017030 | (8S,9S,10R
Specifications & Purity≥98%
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

16α-Hydroxy Progesterone a hydroxylated metabolite of Progesterone that binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.


Application

16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.


Associated Targets(Human)

UGT2B7 Tchem UDP-glucuronosyltransferase 2B7 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (8S,9S,10R,13S,14S,16R,17R)-17-acetyl-16-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
INCHI InChI=1S/C21H30O3/c1-12(22)19-18(24)11-17-15-5-4-13-10-14(23)6-8-20(13,2)16(15)7-9-21(17,19)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17+,18-,19+,20+,21+/m1/s1
InChi Key LOVNYFVWYTXDRE-RMWFXKKMSA-N
Canonical SMILES CC(=O)C1C(CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
Isomeric SMILES CC(=O)[C@H]1[C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PubChem CID 243761
Molecular Weight 330.46

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
L22151045Certificate of AnalysisDec 09, 2022 H336075
L22151082Certificate of AnalysisDec 09, 2022 H336075

Chemical and Physical Properties

SolubilityChloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
SensitivityMoisture sensitive
Melt Point(°C)>212°C (dec.)

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