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17(R)-Resolvin D1 - ~0.01% in ethanol,≥95%, high purity , CAS No.528583-91-7, Agonist of FPR2/ALX;Channel blocker of TRPV3

Moligand™

≥95%
~0.01% in ethanol

CAS#: 528583-91-7
Formula: C₂₂H₃₂O₅
Molecular Weight: 376.49
PubChem CID: 16126783

Item Number

R342110

Grouped product items
SKU	Size	Availability	Price	Qty
R342110-10μg	10μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$237.90
R342110-25μg	25μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$423.90

an exhibitor of a dose-dependent reduction in leukocyte infiltration

View related series

FPR2/ALX Agonist TRPV3 Channel blocker

Basic Description

Specifications & Purity	Moligand™, ≥95%, ~0.01% in ethanol
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST, CHANNEL BLOCKER
Mechanism of action	Agonist of FPR2/ALX;Channel blocker of TRPV3
Product Description	17(R)-Resolvin D1 exhibits a dose-dependent reduction in leukocyte infiltration in a murine model of peritonitis with maximal inhibition of ~35% at a 100 ng dose. In contrast to resolvin D1, the aspirin-triggered form resists rapid inactivation by eicosanoid oxidoreductases.

Associated Targets(Human)

TRPV3 Tchem Transient receptor potential cation channel subfamily V member 3 (1 Activities)

Discover Target: TRPV3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FPR2 Tchem N-formyl peptide receptor 2 (1 Activities)

Discover Target: FPR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
INCHI	InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21+/m1/s1
InChi Key	OIWTWACQMDFHJG-BJEBZIPWSA-N
Canonical SMILES	CCC=CCC(C=CC=CC=CC=CC(C(CC=CCCC(=O)O)O)O)O
Isomeric SMILES	CC/C=C\C[C@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CCC(=O)O)O)O)O
PubChem CID	16126783
UN Number	1170
Packing Group	II
MeSH Entry Terms	7,8,17-trihydroxy-4,9,11,13,15,19-docosahexaenoic acid;aspirin-triggered resolvin D1;AT-RvD1;resolvin D1;RvD1 fatty acid
Molecular Weight	376.49

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
K2218720	Certificate of Analysis	Jul 21, 2022	R342110
K2218778	Certificate of Analysis	Jul 21, 2022	R342110

Solubility

Soluble in water (~0.05 mg/ml at 25.0 °C), PBS pH 7.2, DMF, and DMSO.

Sensitivity

light sensitive

Refractive Index

n20D1.56 (Predicted)

Boil Point(°C)

609.2° C at 760 mmHg

Safety and Hazards(GHS)

Pictogram(s)	GHS07, GHS02
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H225:Highly Flammable liquid and vapor
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P242:Use only non-sparking tools.
Class	3

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17(R)-Resolvin D1 - ~0.01% in ethanol,≥95%, high purity , CAS No.528583-91-7, Agonist of FPR2/ALX;Channel blocker of TRPV3

Basic Description

Product Properties

Associated Targets(Human)

Mechanisms of Action