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(1R,2R)-ML-SI3 - 99%, high purity , CAS No.2418594-00-8

Item Number

M648453

Grouped product items
SKU	Size	Availability	Price
M648453-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
M648453-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
M648453-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$950.90

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Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	(1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 μM) and a weak inhibitor ( IC 50 12.5 μM) of TRPML3.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	(1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 μM) and a weak inhibitor ( IC 50 12.5 μM) of TRPML3 Form:Solid IC50& Target:TRPML1 1.6 μM (IC 50 ) TRPML2 2.3 μM (IC 50 ) TRPML3 12.5 μM (IC 50 )

MCOLN3 Tchem MCOLN3 protein (319 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCOLN1 Tchem Mucolipin-1 (56 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Canonical SMILES	COC1=CC=CC=C1N2CCN(CC2)[C@@H]3CCCC[C@H]3NS(=O)(=O)C4=CC=CC=C4
Isomeric SMILES	COC1=CC=CC=C1N2CCN(CC2)[C@@H]3CCCC[C@H]3NS(=O)(=O)C4=CC=CC=C4
PubChem CID	94784696
Molecular Weight	429.58

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Solubility	DMSO : 50 mg/mL (116.39 mM; Need ultrasonic)

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