(1R,2R)-ML-SI3 - 99%, high purity , CAS No.2418594-00-8

Item Number

M648453

Grouped product items
SKU	Size	Availability	Price
M648453-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
M648453-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
M648453-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$950.90

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Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	(1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 μM) and a weak inhibitor ( IC 50 12.5 μM) of TRPML3.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	(1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 μM) and a weak inhibitor ( IC 50 12.5 μM) of TRPML3 Form:Solid IC50& Target:TRPML1 1.6 μM (IC 50 ) TRPML2 2.3 μM (IC 50 ) TRPML3 12.5 μM (IC 50 )

Associated Targets(Human)

MCOLN3 Tchem MCOLN3 protein (319 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCOLN1 Tchem Mucolipin-1 (56 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCOLN2 Tchem Mucolipin-2 (38 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Canonical SMILES

COC1=CC=CC=C1N2CCN(CC2)[C@@H]3CCCC[C@H]3NS(=O)(=O)C4=CC=CC=C4

Isomeric SMILES

COC1=CC=CC=C1N2CCN(CC2)[C@@H]3CCCC[C@H]3NS(=O)(=O)C4=CC=CC=C4

PubChem CID

Molecular Weight

429.58

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Basic Description