(1S,2S)-Bortezomib - 98%, high purity , CAS No.1132709-14-8

Item Number

S334507

Grouped product items
SKU	Size	Availability	Price
S334507-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$79.90
S334507-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$249.90
S334507-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90
S334507-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$759.90
S334507-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$999.90

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Basic Description

Synonyms	1132709-14-8\|((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid\|(1S,2S)-Bortezomib\|[(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid\|AB01275474-01\|[(1S)-3-methyl-1-[(2S)-3-p
Specifications & Purity	98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Dry ice
Product Description	(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans.

Names and Identifiers

IUPAC Name	[(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
INCHI	InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17+/m0/s1
InChi Key	GXJABQQUPOEUTA-DOTOQJQBSA-N
Canonical SMILES	B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
Isomeric SMILES	B([C@@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
PubChem CID	24871309
Molecular Weight	384.24

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
G2417162	Certificate of Analysis	Apr 02, 2024	S334507
G2417228	Certificate of Analysis	Apr 02, 2024	S334507
G2417230	Certificate of Analysis	Apr 02, 2024	S334507
G2417231	Certificate of Analysis	Apr 02, 2024	S334507
G2417233	Certificate of Analysis	Apr 02, 2024	S334507
G2417243	Certificate of Analysis	Apr 02, 2024	S334507
G2417249	Certificate of Analysis	Apr 02, 2024	S334507
G2417347	Certificate of Analysis	Apr 02, 2024	S334507
G2417359	Certificate of Analysis	Apr 02, 2024	S334507
G2417802	Certificate of Analysis	Apr 02, 2024	S334507

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Basic Description