(1S,2S)-Bortezomib - 98%, high purity , CAS No.1132709-14-8

  • ≥98%
Item Number
S334507
Grouped product items
SKUSizeAvailabilityPrice Qty
S334507-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
S334507-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
S334507-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
S334507-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$759.90
S334507-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

Basic Description

Synonyms1132709-14-8 | ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid | (1S,2S)-Bortezomib | [(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid | AB01275474-01 | [(1S)-3-methyl-1-[(2S)-3-p
Specifications & Purity≥98%
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans.

Associated Targets(Human)

GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APH1A Tbio Gamma-secretase (4915 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PSMB2 Tclin 20S proteasome (530 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lonp1 Lon protease homolog, mitochondrial (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name [(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
INCHI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17+/m0/s1
InChi Key GXJABQQUPOEUTA-DOTOQJQBSA-N
Canonical SMILES B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
Isomeric SMILES B([C@@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
PubChem CID 24871309
Molecular Weight 384.24

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Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2417162Certificate of AnalysisApr 02, 2024 S334507
G2417228Certificate of AnalysisApr 02, 2024 S334507
G2417230Certificate of AnalysisApr 02, 2024 S334507
G2417231Certificate of AnalysisApr 02, 2024 S334507
G2417233Certificate of AnalysisApr 02, 2024 S334507
G2417243Certificate of AnalysisApr 02, 2024 S334507
G2417249Certificate of AnalysisApr 02, 2024 S334507
G2417347Certificate of AnalysisApr 02, 2024 S334507
G2417359Certificate of AnalysisApr 02, 2024 S334507
G2417802Certificate of AnalysisApr 02, 2024 S334507

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