Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 2,2,2-Tribromoethanol | 75-80-9 | Tribromoethanol | Tribromoethyl alcohol | Avertin | Bromethol | Ethobrome | Tribromethanol | Basibrol | Ethobrom | Narcolan | Narcotyl | Narkolan | Rectanol | ETHANOL, 2,2,2-TRIBROMO- | 2,2,2-Tribromoethyl alcohol | .beta.-Tribromoethanol | NSC 2189 | 1329- |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | 2,2,2-Tribromoethanol is generally used as an anesthetic drug for rodents |
Associated Targets(Human)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
POLK Tbio DNA polymerase kappa (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
POLK Tbio DNA polymerase kappa (8653 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SARS-CoV-2 (38078 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Names and Identifiers
| IUPAC Name | 2,2,2-tribromoethanol |
|---|---|
| INCHI | InChI=1S/C2H3Br3O/c3-2(4,5)1-6/h6H,1H2 |
| InChi Key | YFDSDPIBEUFTMI-UHFFFAOYSA-N |
| Canonical SMILES | C(C(Br)(Br)Br)O |
| Isomeric SMILES | C(C(Br)(Br)Br)O |
| WGK Germany | 3 |
| RTECS | KM3675000 |
| PubChem CID | 6400 |
| Molecular Weight | 282.76 |
| Reaxy-Rn | 1733249 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | air&light sensitive |
|---|---|
| Boil Point(°C) | 94°C/11mmHg |
| Melt Point(°C) | 73°C-83.0 °C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
| WGK Germany | 3 |
| RTECS | KM3675000 |
| Reaxy-Rn | 1733249 |
Related Documents
Citations of This Product
| 1. Chaofeng Xing, Minyi Tang, Jianqin Yang, Shuai Wang, Qihua Xu, Wenbin Feng, Yunping Mu, Fanghong Li, Allan Zijian Zhao. (2023) Eicosapentaenoic acid metabolites promotes the trans-differentiation of pancreatic α cells to β cells. BIOCHEMICAL PHARMACOLOGY, 216 (115775). [PMID:37659738] |
| 2. Xiaoyu Zhang, Yuan Gao, Zhuangzhuang Liu, Wenjing Li, Yuan Kang, Ximeng Li, Zhenlu Xu, Cheng Peng, Yun Qi. (2023) Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (1): (320). [PMID:36613764] |
References
| 1. Chaofeng Xing, Minyi Tang, Jianqin Yang, Shuai Wang, Qihua Xu, Wenbin Feng, Yunping Mu, Fanghong Li, Allan Zijian Zhao. (2023) Eicosapentaenoic acid metabolites promotes the trans-differentiation of pancreatic α cells to β cells. BIOCHEMICAL PHARMACOLOGY, 216 (115775). [PMID:37659738] |
| 2. Xiaoyu Zhang, Yuan Gao, Zhuangzhuang Liu, Wenjing Li, Yuan Kang, Ximeng Li, Zhenlu Xu, Cheng Peng, Yun Qi. (2023) Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (1): (320). [PMID:36613764] |